NCT04461730撤回不适用
Role of Basal Ganglia and Thalamus in Perceptual Consciousness and Metacognition
University Hospital, Grenoble0 个研究点开始时间: 2021年12月最近更新:
适应症
试验速览
- 阶段
- 不适用
- 状态
- 撤回
- 发起方
- 主要终点
- Behavioral effect of DBS on confidence
研究概览
简要总结
The term perceptual awareness refers to subjective experience... or the phenomenology associated with the processing of a sensory stimulus. The term metacognition refers to our ability of introspection, knowledge and control of our own cognitive processes. The objective of this research is to establish the contribution of the basal ganglia and thalamus to the perceptual awareness and meta-cognition, using deep brain stimulation coupled with electroencephalography.
研究设计
- 研究类型
- Observational
- 观察模型
- Cohort
- 时间视角
- Prospective
入排标准
- 年龄范围
- 18 Years 至 —（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 是
入选标准
- •Major patient in need of brain stimulation therapy for motor disorders (Parkinson's disease, tremor, dystonia) or psychiatric disorders (OCD).
- •Outpatient or inpatient follow-up
- •Fluent in French and able to understand the study procedures
- •informed consent
- •Patient affiliated to social security
- •Written agreement to participate in the patient's study
- •Intellectual abilities compatible with the performance of cognitive or motor tasks
排除标准
- •Persons referred to in Articles L1121-5 to L1121-8 of the CSP (pregnant women, parturient women, mothers, etc.) who is breastfeeding, person deprived of liberty by judicial or administrative decision, person subject to a legal protection measure
- •Patients in whom transient cessation of stimulation is not tolerated
- •Subject in period of exclusion from another study
- •Subject cannot be contacted in case of emergency
- •Subject under administrative or judicial supervision
结局指标
主要结局
Behavioral effect of DBS on confidence
时间窗: by fall 2024
Confidence in correct and incorrect responses will be compared on and off stimulation
次要结局
- Effect of DBS on EEG markers of confidence(by fall 2024)
研究者
相似试验
已完成
不适用
Neuromodulation of Conscious Perception: Investigating Thalamic Roles Through Ultrasonic StimulationThalamusNCT06083493University of Michigan61
Unknown
不适用
Interactions of Brain Regions in Visuomotor AdaptationHigh Intensity Focused UltrasoundDeep Brain StimulationNCT04190940University of Virginia39
Unknown
不适用
Electrophysiological Activity of the Subthalamic Nucleus During the Processing of Emotional and Motivational InformationParkinsonNCT01537224Rennes University Hospital25
招募中
不适用
Sensory Filtering in the Human Basal Ganglia as a Mechanism of Parkinson's DiseaseParkinson DiseaseNCT05482126University of Alabama at Birmingham30
已完成
不适用
Clinical, Neurophysiological and Radiological Evaluation of Patients With Basal Ganglia LesionsBasal Ganglia LesionsNCT00169325Marie-laure Welter11