Functional Interaction of Thalamus, Basal Ganglia, and the Cerebellum in Visuomotor Adaptation
试验速览
- 阶段
- 不适用
- 入组人数
- 39
- 试验地点
- 2
- 主要终点
- Performance Error on Visuomotor Task
研究概览
简要总结
The purpose of this study is to better understand the roles the cerebellum, basal ganglia, and thalamus play in motor learning. Patients undergoing High Intensity Focused Ultrasound (HIFU) treatment will be receiving an ablation procedure to their thalamus as a part of their medical procedure. Participation in this study will include completing a behavioral task before and after the procedure to see how motor learning task performance differs with and without the thalamus. Similarly, patients undergoing Deep Brain Stimulation (DBS) treatment will have an electrode implanted in their thalamus as a part of their medical procedures. Participation in this study will include completing the motor learning task performance "on" and "off" thalamic electrical stimulation.
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Parallel
- 主要目的
- Other
- 盲法
- None
入排标准
- 年龄范围
- 18 Years 至 85 Years（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Be a patient receiving either high intensity focused ultrasound treatment or deep brain stimulation treatment for Tremor
- •Able to provide informed consent and complete study procedures
- •Must speak English
- •Age 18-85
排除标准
- •Not receiving one of the specified inclusion criteria
- •Unable to provide consent or complete study procedures
- •Women who self-report pregnancy
- •Patients who are currently incarcerated
结局指标
主要结局
Performance Error on Visuomotor Task
时间窗: baseline, a week after HIFU treatment, several weeks after DBS implantation
The visuomotor task has practice, baseline, and experimental trials. Performance on the task will be compared between groups (HIFU treatment and DBS treatment) before and after treatment.
次要结局
未报告次要终点