Biomarkers research for diagnosis of damp-heat syndrome of chronic liver disease
- Conditions
- Chronic hepatitis
- Registration Number
- ITMCTR2000004010
- Lead Sponsor
- Shuguang Hospital Affiliated to Shanghai University of Traditional Chinese Medicine
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Recruiting
- Sex
- All
- Target Recruitment
- Not specified
Meet the criteria for diagnosis of chronic hepatitis B or non-alcoholic fatty liver disease and TCM syndrome diagnosis;
Aged 18-65 years;
Sign informed consent.
1. Patients with other liver diseases such as other hepatotropic virus infection, alcoholic fatty liver, autoimmune diseases, chronic hepatitis B and non-alcoholic fatty liver disease;
2. Patients with chronic severe hepatitis and liver cirrhosis;
3. Accompanied by severe primary disease of heart, kidney, lung, endocrine, blood, metabolism and gastrointestinal tract;
4. Mentally ill;
5. Pregnant or breastfeeding women;
6. Those who have performed gastrointestinal bariatric surgery within the past year or those who have taken weight-loss drugs; within the past 3 months have lost > 10% of their weight.
Study & Design
- Study Type
- Diagnostic test
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Metabolomics;Peripheral blood transcriptomics;
- Secondary Outcome Measures
Name Time Method Blood lipids, fasting blood glucose, AFP, HBV-DNA, hepatitis B markers, HbA1c, fasting insulin;TCM Syndrome Scale;MRI-PDFF;