Tear Collection in Adult Volunteers
Completed
- Conditions
- Healthy Volunteers
- Interventions
- Procedure: Tear Sample Collection
- Registration Number
- NCT01969162
- Lead Sponsor
- Allergan
- Brief Summary
This exploratory study will collect tear samples from adult volunteers for determining and quantifying tear composition profiles. No investigational drug will be administered in this study.
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- COMPLETED
- Sex
- All
- Target Recruitment
- 35
Inclusion Criteria
-Adult volunteers without ocular disease.
Exclusion Criteria
- Systemic medications that could affect eye health taken within 1 month of enrollment
- Eye infection or inflammation in either eye 3 months prior to screening
- History of herpes in either eye
- Diagnosis of dry eye or meibomian gland dysfunction
- Diagnosis of glaucoma
- Allergic conjunctivitis
- Use of rigid contact lenses within 1 year of screening
- Use of soft contact lenses within 1 week of enrollment.
Study & Design
- Study Type
- OBSERVATIONAL
- Study Design
- Not specified
- Arm && Interventions
Group Intervention Description All Participants Tear Sample Collection Adult volunteers without ocular disease who have tear samples collected as per protocol. No investigational drug is administered in this study.
- Primary Outcome Measures
Name Time Method Tear Lipid Composition Profile Day 1 Basal (non-stimulated) tear samples were collected from one eye for lipid analysis. 13 different lipids classes were detected in individual tear samples. The concentration of each lipid class is reported in picomoles (pmole).
- Secondary Outcome Measures
Name Time Method