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Qualitative Evaluation of Tear Fluid and Blood for Auto Antibodies Produced in Response to COVID-19

Completed
Conditions
SARS-CoV 2 Infection
Covid19
Interventions
Diagnostic Test: SARS-CoV2 Autoantibody detection
Registration Number
NCT04542980
Lead Sponsor
Namida Lab
Brief Summary

This study objective is to collect tear and blood samples from individuals with positive SARS-COV2 diagnosis and test those samples for the presence of various SARS-COV2 viral antigens and autoantibodies.

Detailed Description

Not available

Recruitment & Eligibility

Status
COMPLETED
Sex
All
Target Recruitment
44
Inclusion Criteria
  • 18 years of age or older Has been tested for SARS-CoV2 and awaiting results Sample collection for SARS-CoV2 testing Tested positive for SARS-CoV2 virus (confirmed by RT-PCR) prior to enrollment
Exclusion Criteria
  • Under 18 years of age Concurrent eye infection or trauma unrelated to presence of SARS-CoV2 virus. Advanced COVID-19 state what would preclude safe and feasible sample collection.

Study & Design

Study Type
OBSERVATIONAL
Study Design
Not specified
Arm && Interventions
GroupInterventionDescription
SARS-CoV2 PositiveSARS-CoV2 Autoantibody detectionTear Samples: Tear samples will be collected from 100 patients who have tested positive for the SARS-CoV2 virus. A total of 100 Blood samples will be drawn using standard phlebotomy techniques for venipuncture from patients who have tested positive for the SARS-CoV2 virus.
Primary Outcome Measures
NameTimeMethod
Qualitative assessment of IgM and/or IgG by indirect ELISA assay.through study completion, up to 8 months

Determination of the presence or absence of IgM and/or IgG autoantibodies in response to SARS-CoV2 infection. In the case of presence, concentration may be determined as well.

Secondary Outcome Measures
NameTimeMethod

Trial Locations

Locations (1)

Namida Lab

🇺🇸

Fayetteville, Arkansas, United States

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