MedPath

Novel Screening Modality for Early Gastric Cancer

Completed
Conditions
Gastric Cancer
Registration Number
NCT04114006
Lead Sponsor
University of Alabama at Birmingham
Brief Summary

Potential patients will be recruited at participating sites based on routine care with clinical indications for upper endoscopy. Following informed consent, patients will undergo their scheduled endoscopy with standard forceps biopsies along with the transepithelial brush samples. All samples, biopsy and brush samples, will be sent for pathology analysis, per standard clinical practice.

Detailed Description

Potential patients will be recruited at participating sites based on routine care with clinical indications for upper endoscopy. Following informed consent, patients will undergo their scheduled endoscopy with standard forceps biopsies along with the transepithelial brush samples. All samples, biopsy and brush samples, will be sent for histologic analysis, with planned study of the diagnostic yields of each method.

Recruitment & Eligibility

Status
COMPLETED
Sex
All
Target Recruitment
120
Inclusion Criteria
  • Subject is informed of the investigational nature of this study and given verbal and written informed consent in accordance with local, U.S., and international guidelines.
  • Both males and females at least 18 years.
  • Patients with clinical indications for upper endoscopy
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Exclusion Criteria
  • Patients should not have an advanced medical or psychiatric conditions which that may limit their ability to participate in the study, as judged by the physician.
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Study & Design

Study Type
OBSERVATIONAL
Study Design
Not specified
Primary Outcome Measures
NameTimeMethod
Diagnostic yield of the WATS approach versus standard gastric biopsy mapping1-3 Years

To compare the diagnostic yield of the WATS approach versus standard gastric biopsy mapping (per the updated Sydney system).

Secondary Outcome Measures
NameTimeMethod

Trial Locations

Locations (1)

Hospital de Occidente

🇭🇳

Santa Rosa De Copán, Copan, Honduras

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