A comparative study of isobaric ropivacaine with clonidine and isobaric ropivacaine alone in supraclavicular brachial plexus block
Overview
- Phase
- Not Applicable
- Status
- Not yet recruiting
- Sponsor
- Dr Nameirakpam Priyadarshini Devi
- Enrollment
- 100
- Locations
- 1
- Primary Endpoint
- To compare the dose response relationship between isobaric ropivacaine with clonidine and isobaric ropivacaine alone regarding anaesthesia quality and duration
Overview
Brief Summary
The study explores the efficacy of isobaric ropivacaine alone versus isobaric ropivacaine combined with clonidine in supraclavicular brachial plexus blocks for upper extremity surgeries
brachial plexus blocks offer advantages over general anesthesia including reduced risks better pain relief and fewer complications like nausea and vomiting
ropivacaine a local anesthetic works by blocking sodium channels to inhibit nerve impulse conduction selectively targeting pain transmitting fibers with less motor block
clonidine when added to ropivacaine enhances the nerve block by modulating adrenergic pathways leading to prolonged sensory blockade and reduced postoperative pain
the study aims to compare these two approaches to determine which provides better motor blockade longer duration of anesthesia, and improved postoperative pain management
4o mini
Study Design
- Study Type
- Interventional
- Allocation
- Other
- Masking
- None
Eligibility Criteria
- Ages
- 18.00 Year(s) to 55.00 Year(s) (—)
- Sex
- All
Inclusion Criteria
- •ASA physical status I II scheduled for elective upper limb orthopaedic surgeries under supraclavicular brachial plexus block.
Exclusion Criteria
- •Lack of patients consent any other comorbidities COPD IHD HTN DM Renal or hepatic dysfunction etc patients with a known contraindication to any of the study drugs.
Outcomes
Primary Outcomes
To compare the dose response relationship between isobaric ropivacaine with clonidine and isobaric ropivacaine alone regarding anaesthesia quality and duration
Time Frame: every 5 minutes for 30 minutes every 30 minutes during the surgery and every hourly for 12 hours
Secondary Outcomes
- to evaluate whether the addition of clonidine improves pain management reduce the need for opioids and prolongs the duration of analgesia(every 5 minutes for 30 minutes every 30 minutes during the surgery and every hourly for 12 hours)
Investigators
Dr Nameirakpam Priyadarshini Devi
Varun Arjun Medical College and Rohilkhand Hospital