A comparative study of isobaric ropivacaine with clonidine and isobaric ropivacaine alone in supraclavicular brachial plexus block
试验速览
- 阶段
- 不适用
- 状态
- 尚未招募
- 发起方
- 入组人数
- 100
- 试验地点
- 1
- 主要终点
- To compare the dose response relationship between isobaric ropivacaine with clonidine and isobaric ropivacaine alone regarding anaesthesia quality and duration
研究概览
简要总结
The study explores the efficacy of isobaric ropivacaine alone versus isobaric ropivacaine combined with clonidine in supraclavicular brachial plexus blocks for upper extremity surgeries
brachial plexus blocks offer advantages over general anesthesia including reduced risks better pain relief and fewer complications like nausea and vomiting
ropivacaine a local anesthetic works by blocking sodium channels to inhibit nerve impulse conduction selectively targeting pain transmitting fibers with less motor block
clonidine when added to ropivacaine enhances the nerve block by modulating adrenergic pathways leading to prolonged sensory blockade and reduced postoperative pain
the study aims to compare these two approaches to determine which provides better motor blockade longer duration of anesthesia, and improved postoperative pain management
4o mini
研究设计
- 研究类型
- Interventional
- 分配方式
- Other
- 盲法
- None
入排标准
- 年龄范围
- 18.00 Year(s) 至 55.00 Year(s)（—）
- 性别
- All
入选标准
- •ASA physical status I II scheduled for elective upper limb orthopaedic surgeries under supraclavicular brachial plexus block.
排除标准
- •Lack of patients consent any other comorbidities COPD IHD HTN DM Renal or hepatic dysfunction etc patients with a known contraindication to any of the study drugs.
结局指标
主要结局
To compare the dose response relationship between isobaric ropivacaine with clonidine and isobaric ropivacaine alone regarding anaesthesia quality and duration
时间窗: every 5 minutes for 30 minutes every 30 minutes during the surgery and every hourly for 12 hours
次要结局
- to evaluate whether the addition of clonidine improves pain management reduce the need for opioids and prolongs the duration of analgesia(every 5 minutes for 30 minutes every 30 minutes during the surgery and every hourly for 12 hours)
研究者
Dr Nameirakpam Priyadarshini Devi
Varun Arjun Medical College and Rohilkhand Hospital