MedPath

Carboplatin, Paclitaxel and Gemcitabine Hydrochloride With or Without Bevacizumab After Surgery in Treating Patients With Recurrent Ovarian, Epithelial, Primary Peritoneal, or Fallopian Tube Cancer

Phase 3
Active, not recruiting
Conditions
Fallopian Tube Mucinous Adenocarcinoma
Ovarian Clear Cell Adenocarcinofibroma
Ovarian Serous Adenocarcinoma
Primary Peritoneal Undifferentiated Carcinoma
Undifferentiated Carcinoma
Clear Cell Adenocarcinoma
Fallopian Tube Clear Cell Adenocarcinoma
Ovarian Brenner Tumor
Ovarian Clear Cell Adenocarcinoma
Ovarian Transitional Cell Carcinoma
Interventions
Other: Laboratory Biomarker Analysis
Other: Quality-of-Life Assessment
Registration Number
NCT00565851
Lead Sponsor
National Cancer Institute (NCI)
Brief Summary

This randomized phase III trial studies carboplatin, paclitaxel and gemcitabine hydrochloride when given together with or without bevacizumab after surgery to see how well it works in treating patients with ovarian, epithelial, primary peritoneal, or fallopian tube cancer that has come back. Drugs used in chemotherapy, such as carboplatin, paclitaxel and gemcitabine hydrochloride work in different ways to stop the growth of tumor cells, either by killing the cells, by stopping them from dividing, or by stopping them from spreading. Immunotherapy with monoclonal antibodies, such as bevacizumab, may help the body's immune system attack the cancer, and may interfere with the ability of tumor cells to grow and spread. It is not yet known whether combination chemotherapy is more effective when given with or without bevacizumab after surgery in treating patients with ovarian, epithelial, primary peritoneal, or fallopian tube cancer.

Detailed Description

PRIMARY OBJECTIVES:

I. To determine if surgical secondary cytoreduction in addition to adjuvant chemotherapy increases the duration of overall survival in patients with recurrent platinum sensitive epithelial ovarian cancer, peritoneal primary or fallopian tube cancer.

II. To determine if the addition of bevacizumab to the second-line and maintenance phases of treatment increases the duration of overall survival relative to second-line paclitaxel and carboplatin alone in patients with recurrent platinum sensitive epithelial ovarian cancer, peritoneal primary or fallopian tube cancer.

SECONDARY OBJECTIVES:

I. To determine if the addition of bevacizumab to the second-line and maintenance phase of treatment increases the duration of progression-free survival relative to second-line paclitaxel and carboplatin alone in patients with recurrent platinum sensitive epithelial ovarian cancer, peritoneal primary or fallopian tube cancer.

II. To prospectively determine the incidence of carboplatin and paclitaxel hypersensitivity in these patients undergoing retreatment with both agents as first recurrence therapy.

III. To determine if surgical secondary cytoreduction in addition to adjuvant chemotherapy increases quality of life (QOL) in patients with recurrent platinum-sensitive epithelial ovarian cancer, peritoneal primary or fallopian tube cancer, as measured by the Functional Assessment of Cancer Therapy-Ovarian (FACT-O) trial outcome index and Rand Short Form (SF)-36 physical functioning scale.

IV. To determine if the addition of bevacizumab to the second-line and maintenance phases of treatment increases QOL relative to second-line paclitaxel and carboplatin alone in patients with recurrent platinum-sensitive epithelial ovarian, peritoneal primary or fallopian tube cancer.

TRANSLATIONAL RESEARCH OBJECTIVES:

I. To define molecular and biochemical profiles associated with the duration of progression-free survival in platinum-sensitive recurrent ovarian, peritoneal primary or fallopian tube carcinoma treated with combination chemotherapy with or without bevacizumab followed with or without maintenance bevacizumab therapy in the presence or absence of secondary surgical cytoreduction.

II. To identify molecular determinants that predict sensitivity or resistance to carboplatin and paclitaxel with or without bevacizumab followed with or without maintenance bevacizumab therapy.

III. To bank deoxyribonucleic acid (DNA) from whole blood for research and evaluate the association between single nucleotide polymorphisms (SNPs) and measures of clinical outcome including overall survival, progression-free survival and adverse events.

OUTLINE: Patients are assigned to 1 of 4 treatment groups. Patients who are not candidates for surgical cytoreduction (i.e., those for whom complete cytoreduction in the estimation of the investigator is impossible or a medical infirmity precludes exploration and debulking) are eligible to receive chemotherapy after randomization.

Patients who are eligible for surgery undergo abdominal exploration with cytoreduction. Patients are then randomized to 1 of 4 treatment arms.

ARM I: Patients receive paclitaxel intravenously (IV) over 3 hours or docetaxel IV over 1 hour and carboplatin IV over 60 minutes on day 1.

ARM II: Patients receive chemotherapy as in Arm I and bevacizumab IV over 30-90 minutes on day 1.

ARM III: Patients receive gemcitabine hydrochloride IV over 60 minutes on days 1 and 8 and carboplatin as in Arm I.

ARM IV: Patients receive gemcitabine hydrochloride IV as in Arm III, bevacizumab IV and carboplatin IV as in Arm II.

In all arms, courses repeat every 21 days in the absence of disease progression or unacceptable toxicity.

Patients with measurable disease achieving a clinical response (CR) receive 6-8 courses of therapy. Patients with stable disease or partial regression receive a maximum of 8 courses.

Patients without measurable lesions as determined by a computed tomography (CT) scan prior to initiating study treatment continue therapy for 6 courses or, if cancer antigen (CA)-125 normalizes, for 2 courses beyond CA-125 normalization, whichever is greater. Patients in Arm II then receive a maintenance regimen comprising bevacizumab IV over 30-90 minutes. Treatment with bevacizumab alone repeats every 3 weeks in the absence of disease progression or unacceptable toxicity.

After completion of study treatment, patients are followed up every 3 months for 2 years, every 6 months for 3 years, and then yearly for 5 years.

Recruitment & Eligibility

Status
ACTIVE_NOT_RECRUITING
Sex
Female
Target Recruitment
1052
Inclusion Criteria
  • Patients enrolled after August 28, 2011 must be candidates for cytoreductive surgery and consent to have their surgical treatment determined by randomization
  • Patients must have histologic diagnosis of epithelial ovarian carcinoma, peritoneal primary or fallopian tube carcinoma, which is now recurrent
  • Patients with the following histologic epithelial cell types are eligible: serous adenocarcinoma, endometrioid adenocarcinoma, mucinous adenocarcinoma, undifferentiated carcinoma, clear cell adenocarcinoma, mixed epithelial carcinoma, transitional cell carcinoma, malignant Brenner's tumor, or adenocarcinoma not otherwise specified (N.O.S.)
  • Patients must have had a complete response to front-line platinum-taxane therapy (at least three cycles)
  • A complete response to front-line chemotherapy must include: negative physical exam, negative pelvic exam and normalization of CA125, if elevated at baseline; although not required, any radiographic assessment of disease status (e.g. CT, magnetic resonance imaging [MRI], positron emission tomography [PET]/CT, etc) obtained following the completion of primary therapy should be considered negative for disease
  • All patients must have also had a treatment-free interval without clinical evidence of progressive disease of at least 6 months from completion of front-line chemotherapy (both platinum and taxane); front-line therapy may have included a biologic agent (i.e. bevacizumab)
  • Front-line treatment may include maintenance therapy following complete clinical or pathological response; however, maintenance cytotoxic chemotherapy must be discontinued for a minimum of 6 months prior to documentation of recurrent disease; patients receiving maintenance biological therapy or hormonal therapy are ELIGIBLE provided their recurrence is documented more than 6 months from primary cytotoxic chemotherapy completion (includes maintenance chemotherapy) AND a minimum 4 weeks has elapsed since their last infusion of biological therapy
  • Patients must have clinically evident recurrent disease for the purpose of this study
  • Measurable disease (Response Evaluation Criteria in Solid Tumors [RECIST]) is defined as at least one lesion that can be accurately measured in at least one dimension (longest dimension to be recorded); each lesion must be more than or equal to 20 mm when measured by conventional techniques, MRI or CT, or more than or equal to 10 mm when measured by spiral CT
  • Absolute neutrophil count (ANC) greater than or equal to 1,500/mm^3, equivalent to Common Toxicity Criteria for Adverse Events version (v)4.0 (CTCAE) grade 1
  • Platelets greater than or equal to 100,000/mm^3 (CTCAE grade 0-1)
  • Creatinine (non-isotope dilution mass spectrometry [IDMS]) =< 1.5 x institutional upper limit normal (ULN), CTCAE grade 1
  • Total bilirubin =< 1.5 ULN (CTCAE grade 1)
  • Serum glutamic oxaloacetic transaminase (SGOT)/aspartate aminotransferase (AST) =< 2.5 times the upper limit of normal in the absence of liver metastasis; SGOT/AST < 5.0 times ULN in the presence of liver metastasis
  • Alkaline phosphatase =< 2.5 times the upper limit of normal in the absence of liver metastasis; alkaline phosphatase < 5.0 times ULN in the presence of liver metastasis
  • This criterion applies only to the patients enrolled before August 29, 2011 and those enrolled after this date electing to receive bevacizumab; patients must have a urine protein-to-creatinine ratio (UPCR) < 1.0 mg/dL
  • This eligibility criterion does not apply to patients enrolled after August 28, 2011; patients who are not candidates for surgical cytoreduction are eligible for the chemotherapy randomization; patients are not considered candidates for surgical cytoreduction if complete cytoreduction in the estimation of the investigator is impossible or a medical infirmity precludes exploration and debulking
  • Patients must have met the pre-entry requirements as specified
  • Patients must have signed an approved informed consent and authorization permitting release of personal health information
  • Patients must have a Gynecologic Oncology Group (GOG) performance status of 0, 1, or 2
Exclusion Criteria
  • Patients who have received more than one previous regimen of chemotherapy (maintenance is not considered a second regimen)

  • Patients receiving concurrent immunotherapy, or radiotherapy

  • Patients who have received prior radiotherapy to any portion of the abdominal cavity or pelvis are excluded

  • Patients whom have already undergone secondary cytoreduction for recurrent disease are excluded

  • Patients with a prior histologic diagnosis of borderline, low malignant potential (grade 0) epithelial carcinoma that was surgically resected and who subsequently developed an unrelated, new invasive epithelial ovarian or peritoneal primary cancer are eligible provided that they meet the criteria listed above

  • Patients who require parenteral hydration or nutrition and have evidence of partial bowel obstruction or perforation

  • Patients who have received prior chemotherapy for any abdominal or pelvic tumor (other than ovarian, fallopian tube, and primary peritoneal) are excluded

  • Patients with synchronous primary endometrial cancer, or a past history of primary endometrial cancer, are excluded, unless all of the following conditions are met: stage not greater than I-B; no more than superficial myometrial invasion, without vascular or lymphatic invasion; no poorly differentiated subtypes, including papillary serous, clear cell or other International Federation of Gynecology and Obstetrics (FIGO) grade 3 lesions

  • Patients with uncontrolled infection

  • Patients with concurrent severe medical problems unrelated to the malignancy that would significantly limit full compliance with the study or expose the patient to extreme risk or decreased life expectancy

  • Patients with >= grade 2 peripheral neuropathy

  • Patients with a history of allergic reactions to carboplatin and/or paclitaxel or chemically similar compounds; patients with allergic (hypersensitivity) reactions to these chemotherapeutic agents are NOT excluded IF they were successfully retreated following a desensitization program or protocol

  • This criterion applies only to the patients enrolled before August 29, 2011 and those enrolled after this date electing to receive bevacizumab; patients with known hypersensitivity to Chinese hamster ovary cell products or other recombinant human or humanized antibodies

  • Patients of childbearing potential, not practicing adequate contraception, patients who are pregnant or patients who are nursing are not eligible for this trial; to date, no fetal studies in animal or humans have been performed; the possibility of harm to a fetus is likely; bevacizumab specifically inhibits VEGF, which is responsible for the formation of new blood vessels during development, and antibodies can cross the placenta; therefore, bevacizumab should not be administered to pregnant women; in addition, there are unknown immediate and long-term consequences of chemotherapy administration to these women; in addition, surgical exploration as mandated by randomization during pregnancy may cause imminent mortal consequences; further, it is not known whether bevacizumab is excreted in human milk; because many drugs are excreted in human milk, bevacizumab should not be administered to nursing women; subjects will be apprised of the large potential risk to a developing fetus

  • Patients with other invasive malignancies, with the exception of non-melanoma skin cancer, who had (or have) any evidence of the other cancer present within the last 5 years or whose previous cancer treatment contraindicates this protocol therapy

  • This criterion applies only to the patients enrolled before August 29, 2011 and those enrolled after this date electing to receive bevacizumab; patients with active bleeding or pathologic conditions that carry high risk of bleeding such as a known bleeding disorder, coagulopathy, or tumor involving major vessels

  • This criterion applies only to the patients enrolled before August 29, 2011 and those enrolled after this date electing to receive bevacizumab; patients with a history or evidence upon physical examination of central nervous system (CNS) disease, including primary brain tumor, seizures not controlled with standard medical therapy, any brain metastases or a history of stroke within 5 years of the first date of treatment on this study

  • This criterion applies only to the patients enrolled before August 29, 2011 and those enrolled after this date electing to receive bevacizumab; patients with clinically significant cardiovascular disease; this includes:

    • Patients with significant cardiac conduction abnormalities, i.e. PR interval > 0.24 seconds (sec) or 2nd or 3rd degree atrioventricular (AV) block
    • Uncontrolled hypertension, defined as systolic > 150 mm Hg or diastolic > 90 mm Hg
    • Myocardial infarction, cardiac arrhythmia or unstable angina < 6 months prior to registration
    • New York Heart Association (NYHA) grade II or greater congestive heart failure
    • Serious cardiac arrhythmia requiring medication
    • Grade II or greater peripheral vascular disease (exception: episodes of ischemia < 24 hours [hrs] in duration, that are managed non-surgically and without permanent deficit)
    • History of cerebrovascular attack (CVA) within six months
  • This criterion applies only to the patients enrolled before August 29, 2011 and those enrolled after this date electing to receive bevacizumab; patients who have had a major surgical procedure, open biopsy, dental extractions or other dental surgery/procedure that results in an open wound, or significant traumatic injury within 28 days prior to the first date of treatment on this study, or anticipation of need for major surgical procedure during the course of the study; patients with placement of vascular access device or core biopsy within 7 days prior to the first date of treatment on this study

  • Patients undergoing pre-treatment secondary cytoreduction will undergo therapy with bevacizumab on cycle #2

  • Patients undergoing pre-treatment surgery for purposes other than cytoreduction may also participate provided they meet eligibility; patients randomized to arms containing bevacizumab must wait a minimum of 28 days since that procedure to begin protocol treatment; patients who undergo an uncomplicated port placement must wait a minimum of 7 days to begin protocol treatment

Study & Design

Study Type
INTERVENTIONAL
Study Design
PARALLEL
Arm && Interventions
GroupInterventionDescription
Arm I (paclitaxel, docetaxel, carboplatin)CarboplatinPatients receive paclitaxel IV over 3 hours or docetaxel IV over 1 hour and carboplatin over 30 minutes on day 1. Treatment repeats every 21 days.
Arm I (paclitaxel, docetaxel, carboplatin)DocetaxelPatients receive paclitaxel IV over 3 hours or docetaxel IV over 1 hour and carboplatin over 30 minutes on day 1. Treatment repeats every 21 days.
Arm I (paclitaxel, docetaxel, carboplatin)Laboratory Biomarker AnalysisPatients receive paclitaxel IV over 3 hours or docetaxel IV over 1 hour and carboplatin over 30 minutes on day 1. Treatment repeats every 21 days.
Arm II (paclitaxel, docetaxel, carboplatin, bevacizumab)Laboratory Biomarker AnalysisPatients receive chemotherapy as in arm I and bevacizumab IV over 30-90 minutes on day 1. Treatment repeats every 21 days.
Arm II (paclitaxel, docetaxel, carboplatin, bevacizumab)PaclitaxelPatients receive chemotherapy as in arm I and bevacizumab IV over 30-90 minutes on day 1. Treatment repeats every 21 days.
Arm I (paclitaxel, docetaxel, carboplatin)PaclitaxelPatients receive paclitaxel IV over 3 hours or docetaxel IV over 1 hour and carboplatin over 30 minutes on day 1. Treatment repeats every 21 days.
Arm I (paclitaxel, docetaxel, carboplatin)Quality-of-Life AssessmentPatients receive paclitaxel IV over 3 hours or docetaxel IV over 1 hour and carboplatin over 30 minutes on day 1. Treatment repeats every 21 days.
Arm II (paclitaxel, docetaxel, carboplatin, bevacizumab)BevacizumabPatients receive chemotherapy as in arm I and bevacizumab IV over 30-90 minutes on day 1. Treatment repeats every 21 days.
Arm II (paclitaxel, docetaxel, carboplatin, bevacizumab)CarboplatinPatients receive chemotherapy as in arm I and bevacizumab IV over 30-90 minutes on day 1. Treatment repeats every 21 days.
Arm II (paclitaxel, docetaxel, carboplatin, bevacizumab)DocetaxelPatients receive chemotherapy as in arm I and bevacizumab IV over 30-90 minutes on day 1. Treatment repeats every 21 days.
Arm II (paclitaxel, docetaxel, carboplatin, bevacizumab)Quality-of-Life AssessmentPatients receive chemotherapy as in arm I and bevacizumab IV over 30-90 minutes on day 1. Treatment repeats every 21 days.
Arm III (gemcitabine hydrochloride, carboplatin)CarboplatinPatients receive gemcitabine hydrochloride IV over 60 minutes on days 1 and 8 and carboplatin as in Arm I.
Arm III (gemcitabine hydrochloride, carboplatin)Gemcitabine HydrochloridePatients receive gemcitabine hydrochloride IV over 60 minutes on days 1 and 8 and carboplatin as in Arm I.
Arm III (gemcitabine hydrochloride, carboplatin)Laboratory Biomarker AnalysisPatients receive gemcitabine hydrochloride IV over 60 minutes on days 1 and 8 and carboplatin as in Arm I.
Arm III (gemcitabine hydrochloride, carboplatin)Quality-of-Life AssessmentPatients receive gemcitabine hydrochloride IV over 60 minutes on days 1 and 8 and carboplatin as in Arm I.
Arm IV (gemcitabine hydrochloride, bevacizumab, carboplatin)BevacizumabPatients receive gemcitabine hydrochloride IV as in Arm III, bevacizumab IV and carboplatin IV as in Arm II.
Arm IV (gemcitabine hydrochloride, bevacizumab, carboplatin)CarboplatinPatients receive gemcitabine hydrochloride IV as in Arm III, bevacizumab IV and carboplatin IV as in Arm II.
Arm IV (gemcitabine hydrochloride, bevacizumab, carboplatin)Gemcitabine HydrochloridePatients receive gemcitabine hydrochloride IV as in Arm III, bevacizumab IV and carboplatin IV as in Arm II.
Arm IV (gemcitabine hydrochloride, bevacizumab, carboplatin)Laboratory Biomarker AnalysisPatients receive gemcitabine hydrochloride IV as in Arm III, bevacizumab IV and carboplatin IV as in Arm II.
Arm IV (gemcitabine hydrochloride, bevacizumab, carboplatin)Quality-of-Life AssessmentPatients receive gemcitabine hydrochloride IV as in Arm III, bevacizumab IV and carboplatin IV as in Arm II.
Primary Outcome Measures
NameTimeMethod
To Determine if Surgical Secondary Cytoreduction in Addition to Adjuvant Chemotherapy Increases the Duration of Overall Survival in Patients With Recurrent Platinum Sensitive Epithelial Ovarian Cancer, Peritoneal Primary or Fallopian Tube CancerThe time frame is 82.5 months (median duration of follow-up)

The treatment regimens will be compared with a logrank procedure which includes all of the patients categorized by their randomly assigned treatment. The logrank test will be stratified by the secondary surgical debulking status (randomized to undergo cytoreduction, vs randomized to not undergo secondary cytoreduction vs not a candidate or did not consent to secondary surgical cytoreduction) and the duration of treatment free-interval prior to enrolling onto this study (6-12 months vs \> 12 months). The median duration of follow-up is calculated by the reverse Kaplan-Meier method.

To Determine if the Addition of Bevacizumab Increases the Duration of Overall Survival Relative to Second-line Paclitaxel and Carboplatin Alone in Patients With Recurrent Platinum Sensitive Epithelial Ovarian, Peritoneal Primary or Fallopian Tube CancerThe time frame is 82.5 months (median duration of follow-up).

The treatment regimens will be compared with a logrank procedure which includes all of the patients categorized by their randomly assigned treatment. The logrank test will be stratified by the secondary surgical debulking status (randomized to undergo cytoreduction, vs randomized to not undergo secondary cytoreduction vs not a candidate or did not consent to secondary surgical cytoreduction) and the duration of treatment free-interval prior to enrolling onto this study (6-12 months vs \> 12 months). The median duration of follow-up is calculated by the reverse Kaplan-Meier method.

Secondary Outcome Measures
NameTimeMethod
Progression-free Survival (Chemotherapy Analysis)Radiographic assessment of disease was conducted during chemotherapy and then every 6 months during the maintenance / surveillance phase

Progression-free survival was defined as the time from randomization to cancer progression as shown on radiography, according to the RECIST version 1.0 criteria, an increase in the CA125 level according to Gynecologic Cancer InterGroup (GCIG) criteria, global deterioration of health, or death from any cause.

Summary of Adverse Events (CTCAE Version 4.0)During treatment period and up to 100 days after stopping the study treatment, a median duration of 82.5 months

Number of treated patients with at least one adverse event reported (assessed by Common Terminology Criteria for Adverse Events (version 4.0))

Patient Reported Quality of Life (Chemotherapy Analysis)1. Prior to cycle 1 (baseline), 2. Prior to cycle 3 (6 weeks post cycle 1), 3. Prior to cycle 6 (15 weeks post cycle 1), 4. 6 months post cycle 1, 5. 12 months post cycle 1.

Patient reported quality of life was measured with the Treatment Outcome Index (TOI) of the Functional Assessment of Cancer Therapy for ovarian cancer (FACT-O TOI). The FACT-O TOI is a scale for assessing general QOL of ovarian cancer patients. It consists of three subscales: Physical Well Being (7 items), Functional Well Being (7 items), and Ovarian Cancer subscale (11 items). Each item in the FACT-O TOI was scored using a 5-point scale (0=not at all; 1=a little bit; 2=somewhat; 3=quite a bit; 4=very much). The FACT-O TOI score ranges 0-100 with a large score suggests better QOL.

Progression Free Survival (Surgery Analysis)Radiographic assessment of disease (in patients with measurable and non-measurable disease) was conducted Every three months for two years and then every 6 months after completion of chemotherapy during the maintenance/surveillance phase.

Progression-free survival was defined as the time from randomization to cancer progression as shown on radiography, according to the RECIST version 1.0 criteria, an increase in the CA125 level according to Gynecologic Cancer InterGroup (GCIG) criteria, global deterioration of health, or death from any cause.

Patient Reported Physical Function (Chemotherapy Analysis)1. Prior to cycle 1 (baseline), 2. Prior to cycle 3 (6 weeks post cycle 1), 3. Prior to cycle 6 (15 weeks post cycle 1), 4. 6 months post cycle 1, 5. 12 months post cycle 1.

Patient reported physical functioning was measured with physical functioning subscale of the RAND SF-36. The Physical Functioning Subscale consists of 10 items concerning activities of daily living: walking, climbing stairs, bathing, dressing, and performance of physical activities. Each item is rated on a three-point scale of limitation of activity due to the patients' health from 1=limited a lot to 3=not limited. The total PF score is the summation of item scores and then rescaled to 0-100. A larger score suggests better physical functioning.

Patient Reported Quality of Life (Surgery Analysis)1. Prior to surgery, 2. 6 weeks post-surgery, 3. 15 weeks post-surgery, 4. 6 months post-surgery, 5. 12 months post-surgery.

Patient reported quality of life was measured with the Treatment Outcome Index (TOI) of the Functional Assessment of Cancer Therapy for ovarian cancer (FACT-O TOI). The FACT-O TOI is a scale for assessing general QOL of ovarian cancer patients. It consists of three subscales: Physical Well Being (7 items), Functional Well Being (7 items), and Ovarian Cancer subscale (11 items). Each item in the FACT-O TOI was scored using a 5-point scale (0=not at all; 1=a little bit; 2=somewhat; 3=quite a bit; 4=very much). The FACT-O TOI score ranges 0-100 with a large score suggests better QOL.

Patient Reported Physical Functioning (Surgery Analysis)1. Prior to surgery (baseline), 2. 6 weeks post-surgery, 3. 15 weeks post-surgery 4. 6 months post-surgery, 5. 12 months post-surgery

Patient reported physical functioning was measured with physical functioning subscale of the RAND SF-36. The Physical Functioning subscale consists of 10 items concerning activities of daily living: walking, climbing stairs, bathing, dressing, and performance of physical activities. Each item is rated on a three-point scale of limitation of activity due to the patients' health from 1=limited a lot to 3=not limited. The total PF score is the summation of item scores and then rescaled to 0-100. A larger score suggests better physical functioning. This measure was completed by US patients only.

Trial Locations

Locations (712)

Wake Forest University Health Sciences

🇺🇸

Winston-Salem, North Carolina, United States

Sanford Bismarck Medical Center

🇺🇸

Bismarck, North Dakota, United States

Sanford Broadway Medical Center

🇺🇸

Fargo, North Dakota, United States

Southern Oncology Specialists-Huntersville

🇺🇸

Huntersville, North Carolina, United States

Matthews Radiation Oncology Center

🇺🇸

Matthews, North Carolina, United States

Novant Health Cancer Institute - Matthews

🇺🇸

Matthews, North Carolina, United States

Cone Heath Cancer Center at Mebane

🇺🇸

Mebane, North Carolina, United States

Novant Health Cancer Institute - Mooresville

🇺🇸

Mooresville, North Carolina, United States

FirstHealth of the Carolinas-Moore Regional Hospital

🇺🇸

Pinehurst, North Carolina, United States

John Muir Medical Center-Concord

🇺🇸

Concord, California, United States

UCHealth University of Colorado Hospital

🇺🇸

Aurora, Colorado, United States

Banner North Colorado Medical Center

🇺🇸

Greeley, Colorado, United States

Banner McKee Medical Center

🇺🇸

Loveland, Colorado, United States

Intermountain Health Lutheran Hospital

🇺🇸

Wheat Ridge, Colorado, United States

GenesisCare USA - FGO

🇺🇸

Fort Myers, Florida, United States

OSF Saint Joseph Medical Center

🇺🇸

Bloomington, Illinois, United States

Carle at The Riverfront

🇺🇸

Danville, Illinois, United States

OSF Saint Francis Radiation Oncology at Pekin

🇺🇸

Pekin, Illinois, United States

Springfield Memorial Hospital

🇺🇸

Springfield, Illinois, United States

Mission Cancer and Blood - West Des Moines

🇺🇸

Clive, Iowa, United States

Mission Cancer and Blood - Des Moines

🇺🇸

Des Moines, Iowa, United States

Tulane University School of Medicine

🇺🇸

New Orleans, Louisiana, United States

Trinity Health Saint Joseph Mercy Hospital Ann Arbor

🇺🇸

Ann Arbor, Michigan, United States

Trinity Health Medical Center - Brighton

🇺🇸

Brighton, Michigan, United States

Trinity Health Medical Center - Canton

🇺🇸

Canton, Michigan, United States

Chelsea Hospital

🇺🇸

Chelsea, Michigan, United States

Corewell Health Dearborn Hospital

🇺🇸

Dearborn, Michigan, United States

Henry Ford Health Saint John Hospital

🇺🇸

Detroit, Michigan, United States

Henry Ford River District Hospital

🇺🇸

East China Township, Michigan, United States

OSF Saint Francis Hospital and Medical Group

🇺🇸

Escanaba, Michigan, United States

Corewell Health Grand Rapids Hospitals - Butterworth Hospital

🇺🇸

Grand Rapids, Michigan, United States

Henry Ford Saint John Hospital - Academic

🇺🇸

Grosse Pointe Woods, Michigan, United States

Henry Ford Saint John Hospital - Breast

🇺🇸

Grosse Pointe Woods, Michigan, United States

Ascension Borgess Hospital

🇺🇸

Kalamazoo, Michigan, United States

University of Michigan Health - Sparrow Lansing

🇺🇸

Lansing, Michigan, United States

Henry Ford Saint John Hospital - Macomb Medical

🇺🇸

Macomb, Michigan, United States

Henry Ford Warren Hospital - Breast Macomb

🇺🇸

Macomb, Michigan, United States

Corewell Health Lakeland Hospitals - Niles Hospital

🇺🇸

Niles, Michigan, United States

Michigan Healthcare Professionals Pontiac

🇺🇸

Pontiac, Michigan, United States

Trinity Health Saint Joseph Mercy Oakland Hospital

🇺🇸

Pontiac, Michigan, United States

Corewell Health Reed City Hospital

🇺🇸

Reed City, Michigan, United States

Corewell Health William Beaumont University Hospital

🇺🇸

Royal Oak, Michigan, United States

MyMichigan Medical Center Saginaw

🇺🇸

Saginaw, Michigan, United States

Corewell Health Lakeland Hospitals - Marie Yeager Cancer Center

🇺🇸

Saint Joseph, Michigan, United States

Corewell Health Lakeland Hospitals - Saint Joseph Hospital

🇺🇸

Saint Joseph, Michigan, United States

Henry Ford Health Warren Hospital

🇺🇸

Warren, Michigan, United States

Henry Ford Madison Heights Hospital - Breast

🇺🇸

Warren, Michigan, United States

Henry Ford Warren Hospital - GLCMS

🇺🇸

Warren, Michigan, United States

University of Michigan Health - West

🇺🇸

Wyoming, Michigan, United States

MU Health - University Hospital/Ellis Fischel Cancer Center

🇺🇸

Columbia, Missouri, United States

MU Health Care Goldschmidt Cancer Center

🇺🇸

Jefferson City, Missouri, United States

BJC Outpatient Center at Sunset Hills

🇺🇸

Sunset Hills, Missouri, United States

Nebraska Cancer Specialists/Oncology Hematology West PC

🇺🇸

Grand Island, Nebraska, United States

Nebraska Medicine Heartland Hematology Oncology

🇺🇸

Kearney, Nebraska, United States

Dayton Physician LLC - Englewood

🇺🇸

Dayton, Ohio, United States

Saint Alphonsus Cancer Care Center-Baker City

🇺🇸

Baker City, Oregon, United States

Saint Alphonsus Cancer Care Center-Ontario

🇺🇸

Ontario, Oregon, United States

Ballad Health Cancer Care - Bristol

🇺🇸

Bristol, Virginia, United States

Ballad Health Cancer Care - Norton

🇺🇸

Norton, Virginia, United States

Fred Hutchinson Cancer Center

🇺🇸

Seattle, Washington, United States

Saint Michael Cancer Center

🇺🇸

Silverdale, Washington, United States

University of Wisconsin Carbone Cancer Center - University Hospital

🇺🇸

Madison, Wisconsin, United States

Kure Medical Center and Chugoku Cancer Center

🇯🇵

Kure, Hiroshima, Japan

Anchorage Associates in Radiation Medicine

🇺🇸

Anchorage, Alaska, United States

Anchorage Radiation Therapy Center

🇺🇸

Anchorage, Alaska, United States

Alaska Breast Care and Surgery LLC

🇺🇸

Anchorage, Alaska, United States

Alaska Oncology and Hematology LLC

🇺🇸

Anchorage, Alaska, United States

Alaska Regional Hospital

🇺🇸

Anchorage, Alaska, United States

Alaska Women's Cancer Care

🇺🇸

Anchorage, Alaska, United States

Anchorage Oncology Centre

🇺🇸

Anchorage, Alaska, United States

Katmai Oncology Group

🇺🇸

Anchorage, Alaska, United States

Providence Alaska Medical Center

🇺🇸

Anchorage, Alaska, United States

CHI Saint Vincent Cancer Center Hot Springs

🇺🇸

Hot Springs, Arkansas, United States

Sutter Auburn Faith Hospital

🇺🇸

Auburn, California, United States

Sutter Cancer Centers Radiation Oncology Services-Auburn

🇺🇸

Auburn, California, United States

Alta Bates Summit Medical Center-Herrick Campus

🇺🇸

Berkeley, California, United States

Providence Saint Joseph Medical Center/Disney Family Cancer Center

🇺🇸

Burbank, California, United States

Mills-Peninsula Medical Center

🇺🇸

Burlingame, California, United States

Sutter Cancer Centers Radiation Oncology Services-Cameron Park

🇺🇸

Cameron Park, California, United States

Sutter Davis Hospital

🇺🇸

Davis, California, United States

UC San Diego Moores Cancer Center

🇺🇸

La Jolla, California, United States

Long Beach Memorial Medical Center-Todd Cancer Institute

🇺🇸

Long Beach, California, United States

Kaiser Permanente Los Angeles Medical Center

🇺🇸

Los Angeles, California, United States

UCLA / Jonsson Comprehensive Cancer Center

🇺🇸

Los Angeles, California, United States

Memorial Medical Center

🇺🇸

Modesto, California, United States

Palo Alto Medical Foundation-Camino Division

🇺🇸

Mountain View, California, United States

Palo Alto Medical Foundation-Gynecologic Oncology

🇺🇸

Mountain View, California, United States

Sutter Cancer Research Consortium

🇺🇸

Novato, California, United States

UC Irvine Health/Chao Family Comprehensive Cancer Center

🇺🇸

Orange, California, United States

Palo Alto Medical Foundation Health Care

🇺🇸

Palo Alto, California, United States

Stanford Cancer Institute Palo Alto

🇺🇸

Palo Alto, California, United States

Sutter Cancer Centers Radiation Oncology Services-Roseville

🇺🇸

Roseville, California, United States

Sutter Roseville Medical Center

🇺🇸

Roseville, California, United States

Sutter Medical Center Sacramento

🇺🇸

Sacramento, California, United States

California Pacific Medical Center-Pacific Campus

🇺🇸

San Francisco, California, United States

UCSF Medical Center-Mount Zion

🇺🇸

San Francisco, California, United States

Palo Alto Medical Foundation-Santa Cruz

🇺🇸

Santa Cruz, California, United States

Sutter Pacific Medical Foundation

🇺🇸

Santa Rosa, California, United States

Palo Alto Medical Foundation-Sunnyvale

🇺🇸

Sunnyvale, California, United States

Sutter Cancer Centers Radiation Oncology Services-Vacaville

🇺🇸

Vacaville, California, United States

Sutter Solano Medical Center/Cancer Center

🇺🇸

Vallejo, California, United States

John Muir Medical Center-Walnut Creek

🇺🇸

Walnut Creek, California, United States

Rocky Mountain Cancer Centers-Aurora

🇺🇸

Aurora, Colorado, United States

The Medical Center of Aurora

🇺🇸

Aurora, Colorado, United States

Boulder Community Hospital

🇺🇸

Boulder, Colorado, United States

Rocky Mountain Cancer Centers-Boulder

🇺🇸

Boulder, Colorado, United States

Penrose-Saint Francis Healthcare

🇺🇸

Colorado Springs, Colorado, United States

Rocky Mountain Cancer Centers-Penrose

🇺🇸

Colorado Springs, Colorado, United States

Porter Adventist Hospital

🇺🇸

Denver, Colorado, United States

Colorado Blood Cancer Institute

🇺🇸

Denver, Colorado, United States

Presbyterian - Saint Lukes Medical Center - Health One

🇺🇸

Denver, Colorado, United States

Rocky Mountain Cancer Centers-Midtown

🇺🇸

Denver, Colorado, United States

SCL Health Saint Joseph Hospital

🇺🇸

Denver, Colorado, United States

Rocky Mountain Cancer Centers-Rose

🇺🇸

Denver, Colorado, United States

Rose Medical Center

🇺🇸

Denver, Colorado, United States

Western States Cancer Research NCORP

🇺🇸

Denver, Colorado, United States

Mercy Medical Center

🇺🇸

Durango, Colorado, United States

Southwest Oncology PC

🇺🇸

Durango, Colorado, United States

Rocky Mountain Gynecologic Oncology PC

🇺🇸

Englewood, Colorado, United States

Mountain Blue Cancer Care Center - Swedish

🇺🇸

Englewood, Colorado, United States

Swedish Medical Center

🇺🇸

Englewood, Colorado, United States

Mountain Blue Cancer Care Center

🇺🇸

Golden, Colorado, United States

Saint Mary's Hospital and Regional Medical Center

🇺🇸

Grand Junction, Colorado, United States

Rocky Mountain Cancer Centers-Greenwood Village

🇺🇸

Greenwood Village, Colorado, United States

Rocky Mountain Cancer Centers-Lakewood

🇺🇸

Lakewood, Colorado, United States

Saint Anthony Hospital

🇺🇸

Lakewood, Colorado, United States

Rocky Mountain Cancer Centers-Littleton

🇺🇸

Littleton, Colorado, United States

Littleton Adventist Hospital

🇺🇸

Littleton, Colorado, United States

Rocky Mountain Cancer Centers-Sky Ridge

🇺🇸

Lone Tree, Colorado, United States

Sky Ridge Medical Center

🇺🇸

Lone Tree, Colorado, United States

Longmont United Hospital

🇺🇸

Longmont, Colorado, United States

Rocky Mountain Cancer Centers-Longmont

🇺🇸

Longmont, Colorado, United States

Parker Adventist Hospital

🇺🇸

Parker, Colorado, United States

Rocky Mountain Cancer Centers-Parker

🇺🇸

Parker, Colorado, United States

Saint Mary Corwin Medical Center

🇺🇸

Pueblo, Colorado, United States

Rocky Mountain Cancer Centers - Pueblo

🇺🇸

Pueblo, Colorado, United States

North Suburban Medical Center

🇺🇸

Thornton, Colorado, United States

Rocky Mountain Cancer Centers-Thornton

🇺🇸

Thornton, Colorado, United States

Hartford HealthCare - Saint Vincent's Medical Center

🇺🇸

Bridgeport, Connecticut, United States

University of Connecticut

🇺🇸

Farmington, Connecticut, United States

Hartford Hospital

🇺🇸

Hartford, Connecticut, United States

Smilow Cancer Hospital Care Center at Saint Francis

🇺🇸

Hartford, Connecticut, United States

Middlesex Hospital

🇺🇸

Middletown, Connecticut, United States

The Hospital of Central Connecticut

🇺🇸

New Britain, Connecticut, United States

Beebe Medical Center

🇺🇸

Lewes, Delaware, United States

Delaware Clinical and Laboratory Physicians PA

🇺🇸

Newark, Delaware, United States

Helen F Graham Cancer Center

🇺🇸

Newark, Delaware, United States

Medical Oncology Hematology Consultants PA

🇺🇸

Newark, Delaware, United States

Christiana Care Health System-Christiana Hospital

🇺🇸

Newark, Delaware, United States

Beebe Health Campus

🇺🇸

Rehoboth Beach, Delaware, United States

TidalHealth Nanticoke / Allen Cancer Center

🇺🇸

Seaford, Delaware, United States

Christiana Care Health System-Wilmington Hospital

🇺🇸

Wilmington, Delaware, United States

MedStar Washington Hospital Center

🇺🇸

Washington, District of Columbia, United States

AdventHealth Altamonte

🇺🇸

Altamonte Springs, Florida, United States

AdventHealth Kissimmee

🇺🇸

Kissimmee, Florida, United States

AdventHealth Medical Group Urology at Orlando

🇺🇸

Orlando, Florida, United States

AdventHealth Orlando

🇺🇸

Orlando, Florida, United States

AdventHealth East Orlando

🇺🇸

Orlando, Florida, United States

Women's Cancer Associates

🇺🇸

Saint Petersburg, Florida, United States

AdventHealth Winter Park

🇺🇸

Winter Park, Florida, United States

Augusta University Medical Center

🇺🇸

Augusta, Georgia, United States

John B Amos Cancer Center

🇺🇸

Columbus, Georgia, United States

Dekalb Medical Center

🇺🇸

Decatur, Georgia, United States

Northeast Georgia Medical Center-Gainesville

🇺🇸

Gainesville, Georgia, United States

Low Country Cancer Care

🇺🇸

Savannah, Georgia, United States

Memorial Health University Medical Center

🇺🇸

Savannah, Georgia, United States

Summit Cancer Care-Memorial

🇺🇸

Savannah, Georgia, United States

Lewis Cancer and Research Pavilion at Saint Joseph's/Candler

🇺🇸

Savannah, Georgia, United States

Saint Alphonsus Cancer Care Center-Boise

🇺🇸

Boise, Idaho, United States

Saint Luke's Cancer Institute - Boise

🇺🇸

Boise, Idaho, United States

Saint Alphonsus Cancer Care Center-Caldwell

🇺🇸

Caldwell, Idaho, United States

Walter Knox Memorial Hospital

🇺🇸

Emmett, Idaho, United States

Saint Luke's Cancer Institute - Fruitland

🇺🇸

Fruitland, Idaho, United States

Idaho Urologic Institute-Meridian

🇺🇸

Meridian, Idaho, United States

Saint Luke's Cancer Institute - Meridian

🇺🇸

Meridian, Idaho, United States

Saint Alphonsus Cancer Care Center-Nampa

🇺🇸

Nampa, Idaho, United States

Saint Luke's Cancer Institute - Nampa

🇺🇸

Nampa, Idaho, United States

Saint Luke's Cancer Institute - Twin Falls

🇺🇸

Twin Falls, Idaho, United States

Northwest Community Hospital

🇺🇸

Arlington Heights, Illinois, United States

Rush - Copley Medical Center

🇺🇸

Aurora, Illinois, United States

Illinois CancerCare-Bloomington

🇺🇸

Bloomington, Illinois, United States

Illinois CancerCare-Canton

🇺🇸

Canton, Illinois, United States

Memorial Hospital of Carbondale

🇺🇸

Carbondale, Illinois, United States

SIH Cancer Institute

🇺🇸

Carterville, Illinois, United States

Illinois CancerCare-Carthage

🇺🇸

Carthage, Illinois, United States

Centralia Oncology Clinic

🇺🇸

Centralia, Illinois, United States

Northwestern University

🇺🇸

Chicago, Illinois, United States

Rush University Medical Center

🇺🇸

Chicago, Illinois, United States

University of Illinois

🇺🇸

Chicago, Illinois, United States

University of Chicago Comprehensive Cancer Center

🇺🇸

Chicago, Illinois, United States

Cancer Care Specialists of Illinois - Decatur

🇺🇸

Decatur, Illinois, United States

Decatur Memorial Hospital

🇺🇸

Decatur, Illinois, United States

Carle Physician Group-Effingham

🇺🇸

Effingham, Illinois, United States

Crossroads Cancer Center

🇺🇸

Effingham, Illinois, United States

Illinois CancerCare-Eureka

🇺🇸

Eureka, Illinois, United States

Illinois CancerCare-Galesburg

🇺🇸

Galesburg, Illinois, United States

Western Illinois Cancer Treatment Center

🇺🇸

Galesburg, Illinois, United States

Northwestern Medicine Cancer Center Delnor

🇺🇸

Geneva, Illinois, United States

Sudarshan K Sharma MD Limited-Gynecologic Oncology

🇺🇸

Hinsdale, Illinois, United States

Duly Health and Care Joliet

🇺🇸

Joliet, Illinois, United States

Illinois CancerCare-Kewanee Clinic

🇺🇸

Kewanee, Illinois, United States

Illinois CancerCare-Macomb

🇺🇸

Macomb, Illinois, United States

Carle Physician Group-Mattoon/Charleston

🇺🇸

Mattoon, Illinois, United States

Good Samaritan Regional Health Center

🇺🇸

Mount Vernon, Illinois, United States

UC Comprehensive Cancer Center at Silver Cross

🇺🇸

New Lenox, Illinois, United States

Cancer Care Center of O'Fallon

🇺🇸

O'Fallon, Illinois, United States

Illinois CancerCare-Ottawa Clinic

🇺🇸

Ottawa, Illinois, United States

Radiation Oncology of Northern Illinois

🇺🇸

Ottawa, Illinois, United States

Illinois CancerCare-Pekin

🇺🇸

Pekin, Illinois, United States

Illinois CancerCare-Peoria

🇺🇸

Peoria, Illinois, United States

OSF Saint Francis Radiation Oncology at Peoria Cancer Center

🇺🇸

Peoria, Illinois, United States

Methodist Medical Center of Illinois

🇺🇸

Peoria, Illinois, United States

OSF Saint Francis Medical Center

🇺🇸

Peoria, Illinois, United States

Illinois CancerCare-Peru

🇺🇸

Peru, Illinois, United States

Valley Radiation Oncology

🇺🇸

Peru, Illinois, United States

Illinois CancerCare-Princeton

🇺🇸

Princeton, Illinois, United States

Central Illinois Hematology Oncology Center

🇺🇸

Springfield, Illinois, United States

Southern Illinois University School of Medicine

🇺🇸

Springfield, Illinois, United States

Springfield Clinic

🇺🇸

Springfield, Illinois, United States

Southwest Illinois Health Services LLP

🇺🇸

Swansea, Illinois, United States

Carle Cancer Center

🇺🇸

Urbana, Illinois, United States

The Carle Foundation Hospital

🇺🇸

Urbana, Illinois, United States

Northwestern Medicine Cancer Center Warrenville

🇺🇸

Warrenville, Illinois, United States

Rush-Copley Healthcare Center

🇺🇸

Yorkville, Illinois, United States

Elkhart Clinic

🇺🇸

Elkhart, Indiana, United States

Michiana Hematology Oncology PC-Elkhart

🇺🇸

Elkhart, Indiana, United States

Elkhart General Hospital

🇺🇸

Elkhart, Indiana, United States

Indiana University/Melvin and Bren Simon Cancer Center

🇺🇸

Indianapolis, Indiana, United States

Ascension Saint Vincent Indianapolis Hospital

🇺🇸

Indianapolis, Indiana, United States

Community Howard Regional Health

🇺🇸

Kokomo, Indiana, United States

IU Health La Porte Hospital

🇺🇸

La Porte, Indiana, United States

Franciscan Saint Anthony Health-Michigan City

🇺🇸

Michigan City, Indiana, United States

Woodland Cancer Care Center

🇺🇸

Michigan City, Indiana, United States

Michiana Hematology Oncology PC-Mishawaka

🇺🇸

Mishawaka, Indiana, United States

Saint Joseph Regional Medical Center-Mishawaka

🇺🇸

Mishawaka, Indiana, United States

The Community Hospital

🇺🇸

Munster, Indiana, United States

Michiana Hematology Oncology PC-Plymouth

🇺🇸

Plymouth, Indiana, United States

Reid Health

🇺🇸

Richmond, Indiana, United States

Memorial Hospital of South Bend

🇺🇸

South Bend, Indiana, United States

South Bend Clinic

🇺🇸

South Bend, Indiana, United States

Northern Indiana Cancer Research Consortium

🇺🇸

South Bend, Indiana, United States

Michiana Hematology Oncology PC-Westville

🇺🇸

Westville, Indiana, United States

Mercy Cancer Center-West Lakes

🇺🇸

Clive, Iowa, United States

Alegent Health Mercy Hospital

🇺🇸

Council Bluffs, Iowa, United States

Greater Regional Medical Center

🇺🇸

Creston, Iowa, United States

Iowa Methodist Medical Center

🇺🇸

Des Moines, Iowa, United States

Iowa-Wide Oncology Research Coalition NCORP

🇺🇸

Des Moines, Iowa, United States

Mercy Medical Center - Des Moines

🇺🇸

Des Moines, Iowa, United States

Mission Cancer and Blood - Laurel

🇺🇸

Des Moines, Iowa, United States

Iowa Lutheran Hospital

🇺🇸

Des Moines, Iowa, United States

University of Iowa/Holden Comprehensive Cancer Center

🇺🇸

Iowa City, Iowa, United States

Abben Cancer Center

🇺🇸

Spencer, Iowa, United States

Methodist West Hospital

🇺🇸

West Des Moines, Iowa, United States

Mercy Medical Center-West Lakes

🇺🇸

West Des Moines, Iowa, United States

Cancer Center of Kansas - Chanute

🇺🇸

Chanute, Kansas, United States

Cancer Center of Kansas - Dodge City

🇺🇸

Dodge City, Kansas, United States

Cancer Center of Kansas - El Dorado

🇺🇸

El Dorado, Kansas, United States

Cancer Center of Kansas - Fort Scott

🇺🇸

Fort Scott, Kansas, United States

Cancer Center of Kansas-Independence

🇺🇸

Independence, Kansas, United States

Providence Medical Center

🇺🇸

Kansas City, Kansas, United States

University of Kansas Cancer Center

🇺🇸

Kansas City, Kansas, United States

Cancer Center of Kansas-Kingman

🇺🇸

Kingman, Kansas, United States

Lawrence Memorial Hospital

🇺🇸

Lawrence, Kansas, United States

Kansas Institute of Medicine Cancer and Blood Center

🇺🇸

Lenexa, Kansas, United States

Minimally Invasive Surgery Hospital

🇺🇸

Lenexa, Kansas, United States

Cancer Center of Kansas-Liberal

🇺🇸

Liberal, Kansas, United States

Cancer Center of Kansas-Manhattan

🇺🇸

Manhattan, Kansas, United States

Cancer Center of Kansas - McPherson

🇺🇸

McPherson, Kansas, United States

Cancer Center of Kansas - Newton

🇺🇸

Newton, Kansas, United States

Menorah Medical Center

🇺🇸

Overland Park, Kansas, United States

Saint Luke's South Hospital

🇺🇸

Overland Park, Kansas, United States

Cancer Center of Kansas - Parsons

🇺🇸

Parsons, Kansas, United States

Kansas City NCI Community Oncology Research Program

🇺🇸

Prairie Village, Kansas, United States

Cancer Center of Kansas - Pratt

🇺🇸

Pratt, Kansas, United States

Cancer Center of Kansas - Salina

🇺🇸

Salina, Kansas, United States

Cancer Center of Kansas - Wellington

🇺🇸

Wellington, Kansas, United States

Associates In Womens Health

🇺🇸

Wichita, Kansas, United States

Cancer Center of Kansas-Wichita Medical Arts Tower

🇺🇸

Wichita, Kansas, United States

Ascension Via Christi Hospitals Wichita

🇺🇸

Wichita, Kansas, United States

Cancer Center of Kansas - Wichita

🇺🇸

Wichita, Kansas, United States

Wesley Medical Center

🇺🇸

Wichita, Kansas, United States

Wichita NCI Community Oncology Research Program

🇺🇸

Wichita, Kansas, United States

Cancer Center of Kansas - Winfield

🇺🇸

Winfield, Kansas, United States

Flaget Memorial Hospital

🇺🇸

Bardstown, Kentucky, United States

Commonwealth Cancer Center-Corbin

🇺🇸

Corbin, Kentucky, United States

Oncology Hematology Care Inc-Crestview

🇺🇸

Crestview Hills, Kentucky, United States

Saint Joseph Radiation Oncology Resource Center

🇺🇸

Lexington, Kentucky, United States

Saint Joseph Hospital East

🇺🇸

Lexington, Kentucky, United States

Jewish Hospital

🇺🇸

Louisville, Kentucky, United States

The James Graham Brown Cancer Center at University of Louisville

🇺🇸

Louisville, Kentucky, United States

Saints Mary and Elizabeth Hospital

🇺🇸

Louisville, Kentucky, United States

UofL Health Medical Center Northeast

🇺🇸

Louisville, Kentucky, United States

Jewish Hospital Medical Center South

🇺🇸

Shepherdsville, Kentucky, United States

Baton Rouge General Medical Center

🇺🇸

Baton Rouge, Louisiana, United States

Hematology/Oncology Clinic PLLC

🇺🇸

Baton Rouge, Louisiana, United States

Woman's Hospital

🇺🇸

Baton Rouge, Louisiana, United States

West Jefferson Medical Center

🇺🇸

Marrero, Louisiana, United States

Greater Baltimore Medical Center

🇺🇸

Baltimore, Maryland, United States

Sinai Hospital of Baltimore

🇺🇸

Baltimore, Maryland, United States

MedStar Franklin Square Medical Center/Weinberg Cancer Institute

🇺🇸

Baltimore, Maryland, United States

Walter Reed National Military Medical Center

🇺🇸

Bethesda, Maryland, United States

Christiana Care - Union Hospital

🇺🇸

Elkton, Maryland, United States

Northwest Hospital Center

🇺🇸

Randallstown, Maryland, United States

UMass Memorial Medical Center - Memorial Division

🇺🇸

Worcester, Massachusetts, United States

UMass Memorial Medical Center - University Campus

🇺🇸

Worcester, Massachusetts, United States

Michigan Cancer Research Consortium NCORP

🇺🇸

Ann Arbor, Michigan, United States

University of Michigan Comprehensive Cancer Center

🇺🇸

Ann Arbor, Michigan, United States

Bronson Battle Creek

🇺🇸

Battle Creek, Michigan, United States

Spectrum Health Big Rapids Hospital

🇺🇸

Big Rapids, Michigan, United States

Trinity Health IHA Medical Group Hematology Oncology - Brighton

🇺🇸

Brighton, Michigan, United States

Henry Ford Cancer Institute-Downriver

🇺🇸

Brownstown, Michigan, United States

Trinity Health IHA Medical Group Hematology Oncology - Canton

🇺🇸

Canton, Michigan, United States

Caro Cancer Center

🇺🇸

Caro, Michigan, United States

Trinity Health IHA Medical Group Hematology Oncology - Chelsea Hospital

🇺🇸

Chelsea, Michigan, United States

Hematology Oncology Consultants-Clarkston

🇺🇸

Clarkston, Michigan, United States

Newland Medical Associates-Clarkston

🇺🇸

Clarkston, Michigan, United States

Henry Ford Macomb Hospital-Clinton Township

🇺🇸

Clinton Township, Michigan, United States

Henry Ford Medical Center-Fairlane

🇺🇸

Dearborn, Michigan, United States

Wayne State University/Karmanos Cancer Institute

🇺🇸

Detroit, Michigan, United States

Henry Ford Hospital

🇺🇸

Detroit, Michigan, United States

Weisberg Cancer Treatment Center

🇺🇸

Farmington Hills, Michigan, United States

Genesee Cancer and Blood Disease Treatment Center

🇺🇸

Flint, Michigan, United States

Genesee Hematology Oncology PC

🇺🇸

Flint, Michigan, United States

Genesys Hurley Cancer Institute

🇺🇸

Flint, Michigan, United States

Hurley Medical Center

🇺🇸

Flint, Michigan, United States

Genesys Regional Medical Center

🇺🇸

Grand Blanc, Michigan, United States

Cancer Research Consortium of West Michigan NCORP

🇺🇸

Grand Rapids, Michigan, United States

Trinity Health Grand Rapids Hospital

🇺🇸

Grand Rapids, Michigan, United States

Great Lakes Cancer Management Specialists-Van Elslander Cancer Center

🇺🇸

Grosse Pointe Woods, Michigan, United States

Allegiance Health

🇺🇸

Jackson, Michigan, United States

Bronson Methodist Hospital

🇺🇸

Kalamazoo, Michigan, United States

West Michigan Cancer Center

🇺🇸

Kalamazoo, Michigan, United States

Hope Cancer Clinic

🇺🇸

Livonia, Michigan, United States

Trinity Health Saint Mary Mercy Livonia Hospital

🇺🇸

Livonia, Michigan, United States

Saint Mary's Oncology/Hematology Associates of Marlette

🇺🇸

Marlette, Michigan, United States

Mercy Health Partners-Hackley Campus

🇺🇸

Muskegon, Michigan, United States

Trinity Health Muskegon Hospital

🇺🇸

Muskegon, Michigan, United States

Henry Ford Medical Center-Columbus

🇺🇸

Novi, Michigan, United States

McLaren Cancer Institute-Northern Michigan

🇺🇸

Petoskey, Michigan, United States

Hope Cancer Center

🇺🇸

Pontiac, Michigan, United States

Newland Medical Associates-Pontiac

🇺🇸

Pontiac, Michigan, United States

Lake Huron Medical Center

🇺🇸

Port Huron, Michigan, United States

Great Lakes Cancer Management Specialists-Rochester Hills

🇺🇸

Rochester Hills, Michigan, United States

Oncology Hematology Associates of Saginaw Valley PC

🇺🇸

Saginaw, Michigan, United States

Bhadresh Nayak MD PC-Sterling Heights

🇺🇸

Sterling Heights, Michigan, United States

Munson Medical Center

🇺🇸

Traverse City, Michigan, United States

Advanced Breast Care Center PLLC

🇺🇸

Warren, Michigan, United States

Macomb Hematology Oncology PC

🇺🇸

Warren, Michigan, United States

Henry Ford West Bloomfield Hospital

🇺🇸

West Bloomfield, Michigan, United States

Saint Mary's Oncology/Hematology Associates of West Branch

🇺🇸

West Branch, Michigan, United States

Huron Gastroenterology PC

🇺🇸

Ypsilanti, Michigan, United States

Trinity Health IHA Medical Group Hematology Oncology Ann Arbor Campus

🇺🇸

Ypsilanti, Michigan, United States

Sanford Joe Lueken Cancer Center

🇺🇸

Bemidji, Minnesota, United States

Fairview Ridges Hospital

🇺🇸

Burnsville, Minnesota, United States

Mercy Hospital

🇺🇸

Coon Rapids, Minnesota, United States

Saint Luke's Hospital of Duluth

🇺🇸

Duluth, Minnesota, United States

Fairview Southdale Hospital

🇺🇸

Edina, Minnesota, United States

Unity Hospital

🇺🇸

Fridley, Minnesota, United States

Hutchinson Area Health Care

🇺🇸

Hutchinson, Minnesota, United States

Fairview Clinics and Surgery Center Maple Grove

🇺🇸

Maple Grove, Minnesota, United States

Minnesota Oncology Hematology PA-Maplewood

🇺🇸

Maplewood, Minnesota, United States

Saint John's Hospital - Healtheast

🇺🇸

Maplewood, Minnesota, United States

Abbott-Northwestern Hospital

🇺🇸

Minneapolis, Minnesota, United States

Hennepin County Medical Center

🇺🇸

Minneapolis, Minnesota, United States

Health Partners Inc

🇺🇸

Minneapolis, Minnesota, United States

New Ulm Medical Center

🇺🇸

New Ulm, Minnesota, United States

North Memorial Medical Health Center

🇺🇸

Robbinsdale, Minnesota, United States

Metro Minnesota Community Oncology Research Consortium

🇺🇸

Saint Louis Park, Minnesota, United States

Park Nicollet Clinic - Saint Louis Park

🇺🇸

Saint Louis Park, Minnesota, United States

Regions Hospital

🇺🇸

Saint Paul, Minnesota, United States

United Hospital

🇺🇸

Saint Paul, Minnesota, United States

Saint Francis Regional Medical Center

🇺🇸

Shakopee, Minnesota, United States

Lakeview Hospital

🇺🇸

Stillwater, Minnesota, United States

Ridgeview Medical Center

🇺🇸

Waconia, Minnesota, United States

Minnesota Oncology Hematology PA-Woodbury

🇺🇸

Woodbury, Minnesota, United States

Rice Memorial Hospital

🇺🇸

Willmar, Minnesota, United States

Fairview Lakes Medical Center

🇺🇸

Wyoming, Minnesota, United States

Saint Dominic-Jackson Memorial Hospital

🇺🇸

Jackson, Mississippi, United States

Duke Raleigh Hospital

🇺🇸

Raleigh, North Carolina, United States

Annie Penn Memorial Hospital

🇺🇸

Reidsville, North Carolina, United States

Southeast Clinical Oncology Research Consortium NCORP

🇺🇸

Winston-Salem, North Carolina, United States

University of Mississippi Medical Center

🇺🇸

Jackson, Mississippi, United States

Singing River Hospital

🇺🇸

Pascagoula, Mississippi, United States

Central Care Cancer Center - Bolivar

🇺🇸

Bolivar, Missouri, United States

Parkland Health Center-Bonne Terre

🇺🇸

Bonne Terre, Missouri, United States

Cox Cancer Center Branson

🇺🇸

Branson, Missouri, United States

Saint Francis Medical Center

🇺🇸

Cape Girardeau, Missouri, United States

Southeast Cancer Center

🇺🇸

Cape Girardeau, Missouri, United States

Centerpoint Medical Center LLC

🇺🇸

Independence, Missouri, United States

Freeman Health System

🇺🇸

Joplin, Missouri, United States

Mercy Hospital Joplin

🇺🇸

Joplin, Missouri, United States

Saint Luke's Hospital of Kansas City

🇺🇸

Kansas City, Missouri, United States

Heartland Hematology and Oncology Associates Incorporated

🇺🇸

Kansas City, Missouri, United States

Research Medical Center

🇺🇸

Kansas City, Missouri, United States

Saint Luke's East - Lee's Summit

🇺🇸

Lee's Summit, Missouri, United States

Liberty Radiation Oncology Center

🇺🇸

Liberty, Missouri, United States

Delbert Day Cancer Institute at PCRMC

🇺🇸

Rolla, Missouri, United States

Mercy Clinic-Rolla-Cancer and Hematology

🇺🇸

Rolla, Missouri, United States

Heartland Regional Medical Center

🇺🇸

Saint Joseph, Missouri, United States

SSM Health Saint Louis University Hospital

🇺🇸

Saint Louis, Missouri, United States

Saint Louis Cancer and Breast Institute-South City

🇺🇸

Saint Louis, Missouri, United States

Washington University School of Medicine

🇺🇸

Saint Louis, Missouri, United States

Missouri Baptist Medical Center

🇺🇸

Saint Louis, Missouri, United States

Mercy Hospital Saint Louis

🇺🇸

Saint Louis, Missouri, United States

Sainte Genevieve County Memorial Hospital

🇺🇸

Sainte Genevieve, Missouri, United States

Cancer Research for the Ozarks NCORP

🇺🇸

Springfield, Missouri, United States

Mercy Hospital Springfield

🇺🇸

Springfield, Missouri, United States

CoxHealth South Hospital

🇺🇸

Springfield, Missouri, United States

Missouri Baptist Sullivan Hospital

🇺🇸

Sullivan, Missouri, United States

Saint Patrick Hospital - Community Hospital

🇺🇸

Missoula, Montana, United States

CHI Health Good Samaritan

🇺🇸

Kearney, Nebraska, United States

Saint Elizabeth Regional Medical Center

🇺🇸

Lincoln, Nebraska, United States

Nebraska Methodist Hospital

🇺🇸

Omaha, Nebraska, United States

Alegent Health Immanuel Medical Center

🇺🇸

Omaha, Nebraska, United States

Hematology and Oncology Consultants PC

🇺🇸

Omaha, Nebraska, United States

Alegent Health Bergan Mercy Medical Center

🇺🇸

Omaha, Nebraska, United States

Alegent Health Lakeside Hospital

🇺🇸

Omaha, Nebraska, United States

Creighton University Medical Center

🇺🇸

Omaha, Nebraska, United States

Midlands Community Hospital

🇺🇸

Papillion, Nebraska, United States

Women's Cancer Center of Nevada

🇺🇸

Las Vegas, Nevada, United States

Center of Hope at Renown Medical Center

🇺🇸

Reno, Nevada, United States

Renown Regional Medical Center

🇺🇸

Reno, Nevada, United States

Cooper Hospital University Medical Center

🇺🇸

Camden, New Jersey, United States

Hackensack University Medical Center

🇺🇸

Hackensack, New Jersey, United States

The Cancer Institute of New Jersey Hamilton

🇺🇸

Hamilton, New Jersey, United States

Morristown Medical Center

🇺🇸

Morristown, New Jersey, United States

Virtua Memorial

🇺🇸

Mount Holly, New Jersey, United States

Jersey Shore Medical Center

🇺🇸

Neptune, New Jersey, United States

Rutgers Cancer Institute of New Jersey

🇺🇸

New Brunswick, New Jersey, United States

Saint Luke's Hospital-Warren Campus

🇺🇸

Phillipsburg, New Jersey, United States

Overlook Hospital

🇺🇸

Summit, New Jersey, United States

MD Anderson Cancer Center at Cooper-Voorhees

🇺🇸

Voorhees, New Jersey, United States

Virtua Voorhees

🇺🇸

Voorhees, New Jersey, United States

Southwest Gynecologic Oncology Associates Inc

🇺🇸

Albuquerque, New Mexico, United States

University of New Mexico Cancer Center

🇺🇸

Albuquerque, New Mexico, United States

Memorial Medical Center - Las Cruces

🇺🇸

Las Cruces, New Mexico, United States

Women's Cancer Care Associates LLC

🇺🇸

Albany, New York, United States

Island Gynecologic Oncology

🇺🇸

Brightwaters, New York, United States

State University of New York Downstate Medical Center

🇺🇸

Brooklyn, New York, United States

New York-Presbyterian/Brooklyn Methodist Hospital

🇺🇸

Brooklyn, New York, United States

Roswell Park Cancer Institute

🇺🇸

Buffalo, New York, United States

Northwell Health/Center for Advanced Medicine

🇺🇸

Lake Success, New York, United States

Long Island Jewish Medical Center

🇺🇸

New Hyde Park, New York, United States

Laura and Isaac Perlmutter Cancer Center at NYU Langone

🇺🇸

New York, New York, United States

Mount Sinai Hospital

🇺🇸

New York, New York, United States

North Shore University Hospital

🇺🇸

Manhasset, New York, United States

NYP/Columbia University Medical Center/Herbert Irving Comprehensive Cancer Center

🇺🇸

New York, New York, United States

Cone Health Cancer Center at Alamance Regional

🇺🇸

Burlington, North Carolina, United States

UNC Lineberger Comprehensive Cancer Center

🇺🇸

Chapel Hill, North Carolina, United States

Memorial Sloan Kettering Cancer Center

🇺🇸

New York, New York, United States

University of Rochester

🇺🇸

Rochester, New York, United States

Stony Brook University Medical Center

🇺🇸

Stony Brook, New York, United States

State University of New York Upstate Medical University

🇺🇸

Syracuse, New York, United States

Randolph Hospital

🇺🇸

Asheboro, North Carolina, United States

AdventHealth Infusion Center Asheville

🇺🇸

Asheville, North Carolina, United States

Carolinas Medical Center/Levine Cancer Institute

🇺🇸

Charlotte, North Carolina, United States

Novant Health Presbyterian Medical Center

🇺🇸

Charlotte, North Carolina, United States

Oncology Specialists of Charlotte

🇺🇸

Charlotte, North Carolina, United States

Southern Oncology Specialists-Charlotte

🇺🇸

Charlotte, North Carolina, United States

Novant Health Cancer Institute - Huntersville

🇺🇸

Huntersville, North Carolina, United States

Duke University Medical Center

🇺🇸

Durham, North Carolina, United States

Cone Health Cancer Center

🇺🇸

Greensboro, North Carolina, United States

AdventHealth Hendersonville

🇺🇸

Hendersonville, North Carolina, United States

Sanford Roger Maris Cancer Center

🇺🇸

Fargo, North Dakota, United States

Summa Health System - Akron Campus

🇺🇸

Akron, Ohio, United States

Cleveland Clinic Akron General

🇺🇸

Akron, Ohio, United States

Strecker Cancer Center-Belpre

🇺🇸

Belpre, Ohio, United States

Aultman Health Foundation

🇺🇸

Canton, Ohio, United States

Dayton Physicians LLC-Miami Valley South

🇺🇸

Centerville, Ohio, United States

Miami Valley Hospital South

🇺🇸

Centerville, Ohio, United States

Adena Regional Medical Center

🇺🇸

Chillicothe, Ohio, United States

Oncology Hematology Care Inc-Eden Park

🇺🇸

Cincinnati, Ohio, United States

Oncology Hematology Care Inc-Mercy West

🇺🇸

Cincinnati, Ohio, United States

University of Cincinnati Cancer Center-UC Medical Center

🇺🇸

Cincinnati, Ohio, United States

Good Samaritan Hospital - Cincinnati

🇺🇸

Cincinnati, Ohio, United States

Oncology Hematology Care Inc-Anderson

🇺🇸

Cincinnati, Ohio, United States

Case Western Reserve University

🇺🇸

Cleveland, Ohio, United States

Oncology Hematology Care Inc-Kenwood

🇺🇸

Cincinnati, Ohio, United States

Bethesda North Hospital

🇺🇸

Cincinnati, Ohio, United States

Oncology Hematology Care Inc-Blue Ash

🇺🇸

Cincinnati, Ohio, United States

TriHealth Cancer Institute-Westside

🇺🇸

Cincinnati, Ohio, United States

TriHealth Cancer Institute-Anderson

🇺🇸

Cincinnati, Ohio, United States

MetroHealth Medical Center

🇺🇸

Cleveland, Ohio, United States

Cleveland Clinic Cancer Center/Fairview Hospital

🇺🇸

Cleveland, Ohio, United States

Cleveland Clinic Foundation

🇺🇸

Cleveland, Ohio, United States

Ohio State University Comprehensive Cancer Center

🇺🇸

Columbus, Ohio, United States

Mount Carmel East Hospital

🇺🇸

Columbus, Ohio, United States

Riverside Methodist Hospital

🇺🇸

Columbus, Ohio, United States

Columbus Oncology and Hematology Associates Inc

🇺🇸

Columbus, Ohio, United States

Columbus NCI Community Oncology Research Program

🇺🇸

Columbus, Ohio, United States

Grant Medical Center

🇺🇸

Columbus, Ohio, United States

Mount Carmel Health Center West

🇺🇸

Columbus, Ohio, United States

The Mark H Zangmeister Center

🇺🇸

Columbus, Ohio, United States

Doctors Hospital

🇺🇸

Columbus, Ohio, United States

Grandview Hospital

🇺🇸

Dayton, Ohio, United States

Good Samaritan Hospital - Dayton

🇺🇸

Dayton, Ohio, United States

Miami Valley Hospital

🇺🇸

Dayton, Ohio, United States

Miami Valley Hospital North

🇺🇸

Dayton, Ohio, United States

Delaware Health Center-Grady Cancer Center

🇺🇸

Delaware, Ohio, United States

Dayton NCI Community Oncology Research Program

🇺🇸

Dayton, Ohio, United States

Delaware Radiation Oncology

🇺🇸

Delaware, Ohio, United States

Grady Memorial Hospital

🇺🇸

Delaware, Ohio, United States

Oncology Hematology Care Inc-Healthplex

🇺🇸

Fairfield, Ohio, United States

Armes Family Cancer Center

🇺🇸

Findlay, Ohio, United States

Blanchard Valley Hospital

🇺🇸

Findlay, Ohio, United States

Orion Cancer Care

🇺🇸

Findlay, Ohio, United States

Atrium Medical Center-Middletown Regional Hospital

🇺🇸

Franklin, Ohio, United States

Dayton Physicians LLC-Atrium

🇺🇸

Franklin, Ohio, United States

Dayton Physicians LLC-Wayne

🇺🇸

Greenville, Ohio, United States

Wayne Hospital

🇺🇸

Greenville, Ohio, United States

Greater Dayton Cancer Center

🇺🇸

Kettering, Ohio, United States

First Dayton Cancer Care

🇺🇸

Kettering, Ohio, United States

Kettering Medical Center

🇺🇸

Kettering, Ohio, United States

Fairfield Medical Center

🇺🇸

Lancaster, Ohio, United States

Lancaster Radiation Oncology

🇺🇸

Lancaster, Ohio, United States

OhioHealth Mansfield Hospital

🇺🇸

Mansfield, Ohio, United States

Marietta Memorial Hospital

🇺🇸

Marietta, Ohio, United States

OhioHealth Marion General Hospital

🇺🇸

Marion, Ohio, United States

Hillcrest Hospital Cancer Center

🇺🇸

Mayfield Heights, Ohio, United States

UH Seidman Cancer Center at Lake Health Mentor Campus

🇺🇸

Mentor, Ohio, United States

Dayton Physicians LLC-Signal Point

🇺🇸

Middletown, Ohio, United States

Knox Community Hospital

🇺🇸

Mount Vernon, Ohio, United States

Licking Memorial Hospital

🇺🇸

Newark, Ohio, United States

Newark Radiation Oncology

🇺🇸

Newark, Ohio, United States

Southern Ohio Medical Center

🇺🇸

Portsmouth, Ohio, United States

Dayton Physicians LLC-Wilson

🇺🇸

Sidney, Ohio, United States

Springfield Regional Cancer Center

🇺🇸

Springfield, Ohio, United States

Springfield Regional Medical Center

🇺🇸

Springfield, Ohio, United States

Dayton Physicians LLC - Troy

🇺🇸

Troy, Ohio, United States

Upper Valley Medical Center

🇺🇸

Troy, Ohio, United States

Saint Ann's Hospital

🇺🇸

Westerville, Ohio, United States

Wright-Patterson Medical Center

🇺🇸

Wright-Patterson Air Force Base, Ohio, United States

Genesis Healthcare System Cancer Care Center

🇺🇸

Zanesville, Ohio, United States

University of Oklahoma Health Sciences Center

🇺🇸

Oklahoma City, Oklahoma, United States

Natalie Warren Bryant Cancer Center at Saint Francis

🇺🇸

Tulsa, Oklahoma, United States

Warren Clinic-Tulsa South

🇺🇸

Tulsa, Oklahoma, United States

Oklahoma Cancer Specialists and Research Institute-Tulsa

🇺🇸

Tulsa, Oklahoma, United States

Warren Clinic Oncology-Tulsa

🇺🇸

Tulsa, Oklahoma, United States

Saint Charles Health System

🇺🇸

Bend, Oregon, United States

Clackamas Radiation Oncology Center

🇺🇸

Clackamas, Oregon, United States

Providence Cancer Institute Clackamas Clinic

🇺🇸

Clackamas, Oregon, United States

Bay Area Hospital

🇺🇸

Coos Bay, Oregon, United States

Providence Milwaukie Hospital

🇺🇸

Milwaukie, Oregon, United States

Providence Newberg Medical Center

🇺🇸

Newberg, Oregon, United States

Providence Willamette Falls Medical Center

🇺🇸

Oregon City, Oregon, United States

Legacy Good Samaritan Hospital and Medical Center

🇺🇸

Portland, Oregon, United States

Providence Portland Medical Center

🇺🇸

Portland, Oregon, United States

Providence Saint Vincent Medical Center

🇺🇸

Portland, Oregon, United States

Compass Oncology Rose Quarter

🇺🇸

Portland, Oregon, United States

Oregon Health and Science University

🇺🇸

Portland, Oregon, United States

Jefferson Abington Hospital

🇺🇸

Abington, Pennsylvania, United States

Lehigh Valley Hospital-Cedar Crest

🇺🇸

Allentown, Pennsylvania, United States

Saint Luke's University Hospital-Bethlehem Campus

🇺🇸

Bethlehem, Pennsylvania, United States

Lehigh Valley Hospital - Muhlenberg

🇺🇸

Bethlehem, Pennsylvania, United States

Geisinger Medical Center

🇺🇸

Danville, Pennsylvania, United States

Geisinger Medical Center-Cancer Center Hazleton

🇺🇸

Hazleton, Pennsylvania, United States

Penn State Milton S Hershey Medical Center

🇺🇸

Hershey, Pennsylvania, United States

Armstrong Center for Medicine and Health

🇺🇸

Kittanning, Pennsylvania, United States

University of Pennsylvania/Abramson Cancer Center

🇺🇸

Philadelphia, Pennsylvania, United States

Pennsylvania Hospital

🇺🇸

Philadelphia, Pennsylvania, United States

Fox Chase Cancer Center

🇺🇸

Philadelphia, Pennsylvania, United States

Temple University Hospital

🇺🇸

Philadelphia, Pennsylvania, United States

West Penn Hospital

🇺🇸

Pittsburgh, Pennsylvania, United States

Community Medical Center

🇺🇸

Scranton, Pennsylvania, United States

Geisinger Medical Group

🇺🇸

State College, Pennsylvania, United States

Reading Hospital

🇺🇸

West Reading, Pennsylvania, United States

Geisinger Wyoming Valley/Henry Cancer Center

🇺🇸

Wilkes-Barre, Pennsylvania, United States

Women and Infants Hospital

🇺🇸

Providence, Rhode Island, United States

Medical University of South Carolina

🇺🇸

Charleston, South Carolina, United States

Black Hills Obstetrics and Gynecology

🇺🇸

Rapid City, South Dakota, United States

Rapid City Regional Hospital

🇺🇸

Rapid City, South Dakota, United States

Sanford Cancer Center Oncology Clinic

🇺🇸

Sioux Falls, South Dakota, United States

Avera Cancer Institute

🇺🇸

Sioux Falls, South Dakota, United States

Sanford USD Medical Center - Sioux Falls

🇺🇸

Sioux Falls, South Dakota, United States

Bristol Regional Medical Center

🇺🇸

Bristol, Tennessee, United States

Wellmont Medical Associates Oncology and Hematology-Bristol

🇺🇸

Bristol, Tennessee, United States

Memorial Hospital

🇺🇸

Chattanooga, Tennessee, United States

Pulmonary Medicine Center of Chattanooga-Hixson

🇺🇸

Hixson, Tennessee, United States

Wellmont Medical Associates Oncology and Hematology-Johnson City

🇺🇸

Johnson City, Tennessee, United States

Ballad Health Cancer Care - Kingsport

🇺🇸

Kingsport, Tennessee, United States

Wellmont Holston Valley Hospital and Medical Center

🇺🇸

Kingsport, Tennessee, United States

Memorial GYN Plus

🇺🇸

Ooltewah, Tennessee, United States

Texas Tech University Health Sciences Center-Amarillo

🇺🇸

Amarillo, Texas, United States

The Don and Sybil Harrington Cancer Center

🇺🇸

Amarillo, Texas, United States

Dell Seton Medical Center at The University of Texas

🇺🇸

Austin, Texas, United States

Saint Joseph Regional Cancer Center

🇺🇸

Bryan, Texas, United States

MD Anderson in The Woodlands

🇺🇸

Conroe, Texas, United States

Parkland Memorial Hospital

🇺🇸

Dallas, Texas, United States

UT Southwestern/Simmons Cancer Center-Dallas

🇺🇸

Dallas, Texas, United States

Brooke Army Medical Center

🇺🇸

Fort Sam Houston, Texas, United States

University of Texas Medical Branch

🇺🇸

Galveston, Texas, United States

Lyndon Baines Johnson General Hospital

🇺🇸

Houston, Texas, United States

Houston Methodist Hospital

🇺🇸

Houston, Texas, United States

M D Anderson Cancer Center

🇺🇸

Houston, Texas, United States

Memorial Hermann Texas Medical Center

🇺🇸

Houston, Texas, United States

Methodist Willowbrook Hospital

🇺🇸

Houston, Texas, United States

MD Anderson West Houston

🇺🇸

Houston, Texas, United States

MD Anderson League City

🇺🇸

League City, Texas, United States

MD Anderson in Sugar Land

🇺🇸

Sugar Land, Texas, United States

Houston Methodist Sugar Land Hospital

🇺🇸

Sugar Land, Texas, United States

American Fork Hospital / Huntsman Intermountain Cancer Center

🇺🇸

American Fork, Utah, United States

McKay-Dee Hospital Center

🇺🇸

Ogden, Utah, United States

Utah Valley Regional Medical Center

🇺🇸

Provo, Utah, United States

Saint George Regional Medical Center

🇺🇸

Saint George, Utah, United States

Huntsman Cancer Institute/University of Utah

🇺🇸

Salt Lake City, Utah, United States

LDS Hospital

🇺🇸

Salt Lake City, Utah, United States

Central Vermont Medical Center/National Life Cancer Treatment

🇺🇸

Berlin, Vermont, United States

University of Vermont Medical Center

🇺🇸

Burlington, Vermont, United States

University of Vermont and State Agricultural College

🇺🇸

Burlington, Vermont, United States

University of Virginia Cancer Center

🇺🇸

Charlottesville, Virginia, United States

Virginia Commonwealth University/Massey Cancer Center

🇺🇸

Richmond, Virginia, United States

Carilion Clinic Gynecological Oncology

🇺🇸

Roanoke, Virginia, United States

Cancer Care Center at Island Hospital

🇺🇸

Anacortes, Washington, United States

Providence Regional Cancer System-Aberdeen

🇺🇸

Aberdeen, Washington, United States

Swedish Cancer Institute-Eastside Oncology Hematology

🇺🇸

Bellevue, Washington, United States

PeaceHealth Saint Joseph Medical Center

🇺🇸

Bellingham, Washington, United States

PeaceHealth Medical Group PC

🇺🇸

Bellingham, Washington, United States

Harrison HealthPartners Hematology and Oncology-Bremerton

🇺🇸

Bremerton, Washington, United States

Highline Medical Center-Main Campus

🇺🇸

Burien, Washington, United States

Providence Regional Cancer System-Centralia

🇺🇸

Centralia, Washington, United States

Swedish Cancer Institute-Edmonds

🇺🇸

Edmonds, Washington, United States

Saint Elizabeth Hospital

🇺🇸

Enumclaw, Washington, United States

Providence Regional Cancer Partnership

🇺🇸

Everett, Washington, United States

Saint Francis Hospital

🇺🇸

Federal Way, Washington, United States

Swedish Cancer Institute-Issaquah

🇺🇸

Issaquah, Washington, United States

Kadlec Clinic Hematology and Oncology

🇺🇸

Kennewick, Washington, United States

Providence Regional Cancer System-Lacey

🇺🇸

Lacey, Washington, United States

Saint Clare Hospital

🇺🇸

Lakewood, Washington, United States

PeaceHealth Saint John Medical Center

🇺🇸

Longview, Washington, United States

Skagit Regional Health Cancer Care Center

🇺🇸

Mount Vernon, Washington, United States

Harrison HealthPartners Hematology and Oncology-Poulsbo

🇺🇸

Poulsbo, Washington, United States

Virginia Mason Medical Center

🇺🇸

Seattle, Washington, United States

Minor and James Medical PLLC

🇺🇸

Seattle, Washington, United States

Pacific Gynecology Specialists

🇺🇸

Seattle, Washington, United States

Swedish Medical Center-Ballard Campus

🇺🇸

Seattle, Washington, United States

FHCC South Lake Union

🇺🇸

Seattle, Washington, United States

Kaiser Permanente Washington

🇺🇸

Seattle, Washington, United States

Swedish Medical Center-Cherry Hill

🇺🇸

Seattle, Washington, United States

Swedish Medical Center-First Hill

🇺🇸

Seattle, Washington, United States

University of Washington Medical Center - Northwest

🇺🇸

Seattle, Washington, United States

Women's Cancer Center of Seattle

🇺🇸

Seattle, Washington, United States

University of Washington Medical Center - Montlake

🇺🇸

Seattle, Washington, United States

Olympic Medical Cancer Care Center

🇺🇸

Sequim, Washington, United States

Providence Regional Cancer System-Shelton

🇺🇸

Shelton, Washington, United States

MultiCare Deaconess Cancer and Blood Specialty Center - Valley

🇺🇸

Spokane Valley, Washington, United States

Cancer Care Northwest - Spokane South

🇺🇸

Spokane, Washington, United States

MultiCare Deaconess Cancer and Blood Specialty Center - Downtown

🇺🇸

Spokane, Washington, United States

Cancer Care Northwest-Valley

🇺🇸

Spokane, Washington, United States

Cancer Care Northwest-North Spokane

🇺🇸

Spokane, Washington, United States

Evergreen Hematology and Oncology PS

🇺🇸

Spokane, Washington, United States

MultiCare Deaconess Cancer and Blood Specialty Center - North

🇺🇸

Spokane, Washington, United States

Franciscan Research Center-Northwest Medical Plaza

🇺🇸

Tacoma, Washington, United States

MultiCare Tacoma General Hospital

🇺🇸

Tacoma, Washington, United States

Northwest Medical Specialties PLLC

🇺🇸

Tacoma, Washington, United States

Saint Joseph Medical Center

🇺🇸

Tacoma, Washington, United States

PeaceHealth Southwest Medical Center

🇺🇸

Vancouver, Washington, United States

Compass Oncology Vancouver

🇺🇸

Vancouver, Washington, United States

Providence Saint Mary Regional Cancer Center

🇺🇸

Walla Walla, Washington, United States

Wenatchee Valley Hospital and Clinics

🇺🇸

Wenatchee, Washington, United States

Cancer Institutes of Washington PLLC

🇺🇸

Yakima, Washington, United States

North Star Lodge Cancer Center at Yakima Valley Memorial Hospital

🇺🇸

Yakima, Washington, United States

Providence Regional Cancer System-Yelm

🇺🇸

Yelm, Washington, United States

Aurora Health Center-Fond du Lac

🇺🇸

Fond Du Lac, Wisconsin, United States

Aurora Cancer Care-Grafton

🇺🇸

Grafton, Wisconsin, United States

Green Bay Oncology at Saint Vincent Hospital

🇺🇸

Green Bay, Wisconsin, United States

Saint Vincent Hospital Cancer Center Green Bay

🇺🇸

Green Bay, Wisconsin, United States

Saint Vincent Hospital Cancer Center at Saint Mary's

🇺🇸

Green Bay, Wisconsin, United States

Aurora BayCare Medical Center

🇺🇸

Green Bay, Wisconsin, United States

Gundersen Lutheran Medical Center

🇺🇸

La Crosse, Wisconsin, United States

Aurora Bay Area Medical Group-Marinette

🇺🇸

Marinette, Wisconsin, United States

Bay Area Medical Center

🇺🇸

Marinette, Wisconsin, United States

Aurora Saint Luke's Medical Center

🇺🇸

Milwaukee, Wisconsin, United States

Medical College of Wisconsin

🇺🇸

Milwaukee, Wisconsin, United States

Aurora Sinai Medical Center

🇺🇸

Milwaukee, Wisconsin, United States

Cancer Center of Western Wisconsin

🇺🇸

New Richmond, Wisconsin, United States

Saint Vincent Hospital Cancer Center at Oconto Falls

🇺🇸

Oconto Falls, Wisconsin, United States

Vince Lombardi Cancer Clinic - Oshkosh

🇺🇸

Oshkosh, Wisconsin, United States

Vince Lombardi Cancer Clinic-Sheboygan

🇺🇸

Sheboygan, Wisconsin, United States

Saint Vincent Hospital Cancer Center at Sturgeon Bay

🇺🇸

Sturgeon Bay, Wisconsin, United States

Aurora Medical Center in Summit

🇺🇸

Summit, Wisconsin, United States

Vince Lombardi Cancer Clinic-Two Rivers

🇺🇸

Two Rivers, Wisconsin, United States

Aspirus Regional Cancer Center

🇺🇸

Wausau, Wisconsin, United States

Aurora West Allis Medical Center

🇺🇸

West Allis, Wisconsin, United States

Cheyenne Regional Medical Center-West

🇺🇸

Cheyenne, Wyoming, United States

Tohoku University School of Medicine

🇯🇵

Sendai, Aoba-ku, Japan

Hokkaido University Hospital

🇯🇵

Sapporo, Hokkaido, Japan

Iwate Medical University Hospital

🇯🇵

Shiwa-gun, Iwate, Japan

Kagoshima City Hospital

🇯🇵

Kagoshima City, Kagoshima, Japan

Niigata University Medical and Dental Hospital

🇯🇵

Niigata City, Niigata, Japan

Shizuoka Cancer Center

🇯🇵

Shizuoka City, Suntou, Japan

Keio University

🇯🇵

Shinjuku-ku, Tokyo, Japan

Hiroshima University Hospital

🇯🇵

Hiroshima City, Japan

Shikoku Cancer Center

🇯🇵

Matsuyama, Japan

National Kyushu Cancer Center

🇯🇵

Minami-ku, Japan

Jikei University School of Medicine

🇯🇵

Minato-ku, Tokyo, Japan

Kindai University

🇯🇵

Osaka, Japan

Saitama Medical University International Medical Center

🇯🇵

Saitama, Japan

National Cancer Center Hospital

🇯🇵

Tokyo, Japan

Tottori University

🇯🇵

Tottori, Japan

Keimyung University-Dongsan Medical Center

🇰🇷

Dalseo-gu, Daegu, Korea, Republic of

National Cancer Center-Korea

🇰🇷

Goyang-si, Gyeonggi-do, Korea, Republic of

Samsung Medical Center

🇰🇷

Seoul, Korea, Korea, Republic of

Catholic University of Korea-Seoul Saint Mary's Hospital

🇰🇷

Seoul, Korea, Korea, Republic of

Seoul National University Bundang Hospital

🇰🇷

Seongnam City, Kyeonggi-do, Korea, Republic of

Gachon University Gil Hospital

🇰🇷

Incheon, Korea, Republic of

Asan Medical Center

🇰🇷

Seoul, Korea, Republic of

Gangnam Severance Hospital

🇰🇷

Seoul, Korea, Republic of

Seoul National University Hospital

🇰🇷

Seoul, Korea, Republic of

Kyung Hee University Hospital at Gangdong

🇰🇷

Seoul, Korea, Republic of

Korea Cancer Center Hospital

🇰🇷

Seoul, Korea, Republic of

Ewha Woman's University

🇰🇷

Seoul, Korea, Republic of

Ajou University Hospital

🇰🇷

Suwon, Korea, Republic of

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