Endoscopic ultrasound guided gastrojejunostomy versus laparoscopic gastrojejunostomy for palliative management of malignant gastric outlet obstruction: a randomized controlled trial

Dr Jayanta Samanta0 个研究点目标入组 0 人开始时间: 待定最近更新: 2023年8月21日

试验速览

暂无简介。

•1.Patients = 18 years of age with malignant symptomatic gastric outlet obstruction (GOO) requiring intervention with an unresectable malignant lesion (biopsy proven) or borderline/ locally advanced planned for neo-adjuvant therapy prior to surgery.
•2.GOO confirmed endoscopically or radiologically.
•3.GOOS (gastric outlet obstruction score) 0 (no oral intake) or 1 (only liquids).
•4.The patient who gives informed consent for participation in the study.

•1.Lack of informed consent
•2.Pregnancy
•3.Coagulation disorder (INR >1.5 or platelet count <50000/ul)
•4.Multiple level bowel obstruction confirmed radiologically (contrast study or computed tomography scans)
•5.Prior endoscopic or surgical treatment for GOO.
•6.Severe comorbidities precluding endoscopic treatment (cardiorespiratory instability, severe pulmonary disease, bleeding disorder)
•7.Previous gastric, periampullary or duodenal surgery
•8.Complete GOO evidenced by inability to either pass a wire/nasojejunal tube across the stricture and/or inability to opacify small bowel distal to the malignant stricture
•9.Malignant conditions involving the stomach such as Linitis plastica, malignancy of the proximal stomach etc.
•10.Life expectancy of less than 1 month

发起方

Dr Jayanta Samanta