Efficacy of C-PRF Versus i-PRF on Gingival Thickness & Keratinized Tissue Width in Subjects With Thin Gingival Biotype: ( Split Mouth Controlled Clinical Trials)
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 发起方
- 入组人数
- 10
- 试验地点
- 2
- 主要终点
- measure the mean differences gain of GT&KTW
研究概览
简要总结
Randomized split mouth clinical trials study focused on comparing the efficacy of i-prf versus c-prf injections on gingival thickness and keratinized tissue width in subjects with thin gingival biotype.
详细描述
Randomized split mouth clinical trials study focused on comparing the efficacy of i-prf versus c-prf injections on gingival thickness and keratinized tissue width in subjects with thin gingival biotype.
Gingival biotype is an important clinical parameter that plays an important role in determining the gingival health in the future and the possibility of developing gingival recession or other gingival unhealthy condition that is related to thin gingival biotype.
Gingival biotype is consist of gingival thickness and keratinized tissue width, and its either thin or thick, and the later is more favourable to withstand the developing of gingival diseases and unhealthy condition, with this study we compare the effect of i-PRF injection which is approved in many previous clinical trials that it affects the gingival biotype and increases gingival thickness and the keratinized tissue width, and compare it to newly developed PRF generation (C-PRF) which is Concentrated Platelet Rich Fibrin.
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Single Group
- 主要目的
- Treatment
- 盲法
- Double (Participant, Outcomes Assessor)
入排标准
- 年龄范围
- 18 Years 至 —（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 是
入选标准
- •Age ≥18 years and no systemic disease or pregnancy.
- •Non-smoker.
- •Subjects with clinically healthy intact periodontium; bleeding on probing (BOP)<10%, probing pocket depth (PPD)≤3mm, intact periodontium (no probing attachment loss). (Chapple et al., 2018).
- •Four non-adjacent sites of anterior region with thin gingival biotype (GT ≤ 1mm). (Patrick H. et al., 2018).
- •No malocclusion, crowding, filling, missing or supernumerary mandibular anterior teeth.
- •No blood-borne conditions.
- •Any symptoms of recent acute illness e.g., COVID-
- •Exclusion Criteria
- •Active orthodontic treatment.
- •Previous periodontal surgery.
- •Use of blood thinners.
- •Use of any drugs that might lead to gingival enlargement.
- •Gingival Recession.
- •Thick gingival biotype.
排除标准
- 未提供
结局指标
主要结局
measure the mean differences gain of GT&KTW
时间窗: baseline and 3 months
the increase in gingival thickness and keratinized tissue width after the injection of prf concentrates.
次要结局
- measure the mean difference gain of GT&KTW(baseline and 1 month)
研究者
Sajjad Ahmed Shakir
bachelor of dental surgery
University of Baghdad