Pre-emptive intravenous ketorolac analgesia does not alter the risk of bleeding after tonsillectomy in childre
Completed
- Conditions
- the use of non-steroidal anti-inflammatory drugs for post-tonsillectomy analgesia in childrenAnaesthesiology - Anaesthetics
- Registration Number
- ACTRN12613001203741
- Lead Sponsor
- king Abdulaziz Naval Base Hospital.
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Completed
- Sex
- All
- Target Recruitment
- 147
Inclusion Criteria
ASA physical status I children scheduled for tonsillectomy with or without adenoidectomy. All patients enrolled in this study had normal blood counts, with normal coagulation profile (prothrombin time, activated partial thromboplastin time, platelet count, and bleeding time.
Exclusion Criteria
Exclusion criteria included the use of paracetamol or NSAIDs within 6 h or any other analgesic medication within 12 h before surgery, and a known allergy to any of the study drugs.
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method The primary outcome measures was the difference between the two groups as regards the hemoglobin level. Hemoglobin (Hb) level was measured in the laboratory as a part of the routine preoperative preparation for tonsillectomy at the hospital. Additionally, non-invasive hemoglobin level (SpHb) was assessed at the same time when blood was drawn from the child for the routine preoperative laboratory investigations, using a multi-wavelength pulse oximetry.SpHb measurement was assessed on arrival at the post anesthesia care unit (PACU) and repeated at 12h, 24h postoperatively and another measurement was obtained at the 7th postoperative day. [the 7th postoperative day]
- Secondary Outcome Measures
Name Time Method the difference between the two groups as regards the pain scores ., pain intensity was assessed by an anesthesiologist, blinded to the treatment group using an objective pain score (OPS) immediately upon PACU admission, then 30min, 1h, 2h, 4h, and 6h postoperatively. This OPS took into account the child’s blood pressure, crying, movement and agitation, with each variable scoring 0–2 points (best to worst). [6h postoperatively];The incidence of postoperative vomiting [24h after surgery]