ocal versus intravenous ketorolac for postoperative pain control after lumbar spinal fusio
Phase 4
- Conditions
- Postoperative pain following spinal fusion surgery can lead to a series of significant complicationslocal and intravenous ketorolac, postoperative pain, lumbar spinal fusion
- Registration Number
- TCTR20231030002
- Lead Sponsor
- Institutional Review Board Royal Thai Army Medical Department
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Enrolling by invitation
- Sex
- All
- Target Recruitment
- 75
Inclusion Criteria
1. Ages of 20 and 75
2. undergoing lumbar spinal fusion between 1-3 levels
3. no history of long-term opioid use
4. Patients who are ASA classification 1-3
Exclusion Criteria
1.Ongoing infection
2.History of cancer
3.Allergic to ketorolac or analgesia
4.Smoking
5.Contraindication for NSAIDs : chronic kidney disease(GFR<60 ml/min/1.73m2)
6.Patients who had history of GI bleeding and gastritis
7.Previous back surgery
8.Unwilling to participate in the study
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Postoperative morphine consumption per day (administered using a patient-controlled analgesia pump) postoperative day0-3 Postoperative morphine consumption per hous
- Secondary Outcome Measures
Name Time Method Pain score at specific hours after the operation postoperative until discharge visual analog scale (VAS),Satisfaction postoperative until discharge Questionaire,Drain output postoperative until drain removed ml. per day,Length of stay postoperative until discharge day,renal side effect postoperative day1 creatinine clearance on postoperative day1,Fusion rate at 1 year (by CT scan) at 12 months after intervention CT scan