Laser Therapy on Burned Skin
试验速览
- 阶段
- 不适用
- 状态
- 终止
- 入组人数
- 4
- 试验地点
- 1
- 主要终点
- Skin blood flow
研究概览
简要总结
The purpose of this study is to examine effects of laser therapy on blood flow and sweating responses in burn-injured skin.
详细描述
This is a longitudinal study in which the effects of laser therapy on cutaneous vascular responses and sweating of the treated areas are assessed. Specifically, burn survivors who will undergo standard of care laser therapy to treat burn-related scars will perform whole-body heating and local heating procedures prior to the initiation of laser therapy, at an intermediate point during the laser therapy regimen, and upon conclusion of the laser therapy regimen.
For this pilot investigation a placebo will not be incorporated.
Primary outcome variables will be skin blood flow and sweating responses from skin treated with laser therapy and adjacent untreated/uninjured skin.
研究设计
- 研究类型
- Observational
- 观察模型
- Cohort
- 时间视角
- Prospective
入排标准
- 年龄范围
- 18 Years 至 65 Years（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •18-65 years old
- •Experience a severe burn injury that warrant laser therapy.
- •Free of any significant underlying medical problems based upon a detailed medical history and physical exam
排除标准
- •Known heart disease
- •Other chronic medical conditions requiring regular medical therapy including cancer, diabetes, uncontrolled hypertension, and uncontrolled hypercholesterolemia.
- •Abnormality detected on routine screening suggestive of cardiac ischemia or previously undetected cardiac disease or resting left bundle branch block on screening electrocardiogram.
- •Subject with a body mass index >35 kg/m2
- •Pregnant or planning to become pregnant within the subsequent 6 months.
结局指标
主要结局
Skin blood flow
时间窗: Upwards to 6 months after the final laser treatment
Primary outcome variables will be skin blood flow and sweating responses from skin treated with laser therapy and adjacent untreated/uninjured skin.
次要结局
未报告次要终点
研究者
Craig Crandall
Professor of Medicine
University of Texas Southwestern Medical Center