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临床试验/NCT02498730
NCT02498730已完成不适用

Can the High Intensity Interval Training (HIIT) Deliver Superior and Rapid Decrease of Symptoms of Bipolar Disorder? a Controlled and Randomized Study

Universidade Federal do Rio de Janeiro1 个研究点 分布在 1 个国家目标入组 36 人开始时间: 2015年8月最近更新:
适应症

试验速览

阶段
不适用
状态
已完成
入组人数
36
试验地点
1
主要终点
Symptom Scales (Hamilton and Young)

研究概览

简要总结

Our main objective will be to evaluate the chronic effects (12 weeks) of high-intensity interval training compared to moderate intensity (same total work) on reducing the symptoms of bipolar disorder, cortical changes, as well as on the VO2max. In addition, the investigators will establish what influence of gain to VO2max has on reducing symptoms.

详细描述

Physical exercise has significant effects on health promotion and the consequent reduction of the severity of bipolar disorder (BD). This review establishes a pattern of response of exercise and potential impact on the pathophysiology of BD; , as well as, produces hypotheses on how acute and chronic effect of exercises may act differently; and provides future perspectives with the focus of the exercise as an important and innovative model of treatment for BD and mental disorder. A critical evaluation of the literature was undertaken including the influence of exercise on health promotion in patients with mental disorders, neurochemical behavior exercise-induced, as well as reflective introduction of news perspectives of training control in severe exercise domain. The exercise induces significant changes in monoaminergic after, and with long-term training, and work with a threshold of exercise can modulate positive effects on mood. Fast adaptive effects from the high intensity interval training should be considered in BD patients. However, there must be caution in his administration. We speculate that exercise may be a way of maintaining euthymia in the case of BD, making it less vulnerable patient to stay longer at a time of neutrality. Future research is needed to adopt a training strategy that is both time efficient in the different areas and adequate for the population in question.

研究设计

研究类型
Interventional
分配方式
Randomized
干预模型
Parallel
主要目的
Treatment
盲法
None

入排标准

年龄范围
18 Years 至 59 Years(Adult)
性别
All
接受健康志愿者

入选标准

  • Bipolar Criteria (DSM-IV),
  • sedentary lifestyle

排除标准

  • 60 and over,
  • Cardiovascular Disease,
  • Panic disorder,
  • Metabolic syndrome Diagnosis

结局指标

主要结局

Symptom Scales (Hamilton and Young)

时间窗: 0 week, 6 week, 12 week

Variable Measured to reduction of symptoms

次要结局

  • Cortical Changes (EEG) - Loreta(0 week, 6 week, 12 week)
  • Cognitive Function(0 week, 6 week, 12 week)
  • VO2Max(0 week, 6 week, 12 week)

研究者

申办方类型
Other
责任方
Principal Investigator
主要研究者

Alberto Souza de Sá Filho

Doctorade in Mental Health

Universidade Federal do Rio de Janeiro

研究点 (1)

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