ChiCTR-OOC-15006761尚未招募Unknown
Effects of Particulate Air Pollution on Corticosteroid Insensitivity in Patients with Chronic Obstructive Pulmonary Disease: Roles of Histone deacetylases and Autophagy
未提供1 个研究点 分布在 1 个国家目标入组 180 人开始时间: 2015年8月1日最近更新:
适应症
试验速览
- 阶段
- Unknown
- 状态
- 尚未招募
- 入组人数
- 180
- 试验地点
- 1
- 主要终点
- Inflammation
研究概览
简要总结
The objective of this study is to investigate the association between particulate air pollution and corticosteroid insensitivity in COPD patients.
研究设计
- 研究类型
- Observational
入排标准
- 年龄范围
- 40 至 80（—）
- 性别
- All
入选标准
- •COPD patients: Inclusion criteria:
- •Willing and signed informed consent;
- •males or females aged between 40 y/o to 80 y/o;
- •diagnosed with COPD by physicians;
- •FEV1/FVC< 70% predicted.
排除标准
- •COPD patients Exclusion criteria:
- •known asthma, bronchiectasis, tuberculosis, pneumoconiosis, or other pulmonary diseases;
- •malignancy;
- •acute exacerbation or infection in 3 months.
- •Normal non-smokers and healthy smokers Exclusion criteria:
- •any acute infections, including upper airway infection, in 3 months;
- •Known major acute or chronic medial diseases.
研究组 & 干预措施
Case series
Nil
结局指标
主要结局
Inflammation
次要结局
未报告次要终点
研究者
研究点 (1)
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