Evaluation of the Clinical Effectiveness of Pericapsular Nerve Group (PENG) Block and Pulsed Radiofrequency Applications in Chronic Hip Pain
试验速览
- 阶段
- 不适用
- 状态
- 招募中
- 入组人数
- 84
- 试验地点
- 1
- 主要终点
- Change in pain intensity measured by the Visual Analog Scale (VAS, 0-10; higher scores indicate worse pain)
研究概览
简要总结
The primary aim of this study is to prospectively compare the effects of the pericapsular nerve group (PENG) block alone and the combination of PENG block with pulsed radiofrequency (PRF) on pain intensity in patients with chronic hip pain. As a secondary aim, the effects of both treatment modalities on hip function are intended to be evaluated using valid and reliable functional assessment scales. Through this study, it is aimed to demonstrate the clinical contribution of adding PRF to the PENG block and to identify a more effective and longer-lasting approach for the interventional treatment of chronic hip pain.
详细描述
Chronic hip pain is a common clinical condition, particularly in the elderly, that significantly impairs quality of life and leads to functional limitation and dependence in daily activities. Chronic hip pain caused by degenerative, inflammatory, and mechanical conditions-most notably hip osteoarthritis-often remains inadequately controlled despite medical treatment, physical therapy, and rehabilitation. Although surgical interventions can be effective, they are not suitable for all patients due to advanced age, comorbidities, or surgical contraindications. Therefore, minimally invasive interventional pain management techniques have gained increasing importance in the treatment of chronic hip pain.
The nociceptive innervation of the hip joint primarily arises from the anterior capsule, which is mainly supplied by the sensory branches of the femoral, obturator, and accessory obturator nerves. Based on this anatomical rationale, the pericapsular nerve group (PENG) block is an ultrasound-guided technique that targets these sensory fibers to provide effective analgesia without causing motor blockade. Previous studies have shown that the PENG block reduces pain scores and improves functional mobility in both acute and chronic hip pain; however, its analgesic effect may be time-limited, requiring repeated applications in some patients.
Pulsed radiofrequency (PRF), unlike conventional thermal radiofrequency, aims to modulate nerve transmission without causing tissue destruction and may provide longer-lasting analgesia through neuromodulatory mechanisms. Recent evidence suggests that combining PRF with peripheral nerve blocks may prolong analgesic effects compared with nerve blocks alone. However, prospective studies directly comparing PENG block alone with PENG block combined with PRF in chronic hip pain are limited, highlighting the need for further investigation.
研究设计
- 研究类型
- Observational
- 观察模型
- Other
- 时间视角
- Prospective
入排标准
- 年龄范围
- 18 Years 至 80 Years(Adult, Older Adult)
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Presence of chronic hip pain lasting at least 3 months
- •Baseline Visual Analog Scale (VAS) score ≥ 4
- •Clinical and/or radiological diagnosis of hip osteoarthritis
- •Inadequate response to conservative treatments
排除标准
- •Local or systemic infection at the intervention site
- •Coagulopathy or inability to discontinue anticoagulant therapy
- •Hip pain related to malignancy
- •History of previous hip arthroplasty
- •Severe neurological deficit
- •Pregnancy or breastfeeding
研究组 & 干预措施
Group PENG
The initial step in patients diagnosed with chronic hip pain is a diagnostic intervention, namely the application of a pericapsular nerve group (PENG) block. In patients who benefit from the diagnostic block-defined as a reduction of 50% or more in VAS scores following the procedure-pulsed radiofrequency (PRF) treatment is added as a second-stage intervention. This stepwise approach reflects standard clinical practice, and both procedures are commonly used in clinical praqctice for the management of chronic hip pain. However, the available evidence in the literature on this approach is largely limited to case reports and retrospective case series. The aim of the present study is to document and share the clinical outcomes of this treatment strategy routinely applied in clinical practice.
干预措施: PENG Block Pulsed radiofrequency (Procedure)
结局指标
主要结局
Change in pain intensity measured by the Visual Analog Scale (VAS, 0-10; higher scores indicate worse pain)
时间窗: baseline (pre-procedure) and at 1 week, 1 month, 3 months, and 6 months after the procedure.
Pain intensity will be assessed using the Visual Analog Scale (VAS), a validated pain measurement tool ranging from 0 to 10, where 0 indicates no pain and 10 represents the worst pain imaginable.
次要结局
- Change in Pain, Stiffness, and Physical Function Measured by the Western Ontario and McMaster Universities Osteoarthritis Index (WOMAC, 0-96)(baseline (pre-procedure) and at 1 week, 1 month, 3 months, and 6 months after the procedure.)
- Change in Hip Function Measured by the Harris Hip Score (HHS, 0-100)(Baseline (pre-procedure), 1 week, 1 month (primary functional endpoint), 3 months, and 6 months after pulsed radiofrequency (PRF) treatment.)
- Secondary Outcome: TAnalgesic Use(Baseline and at 1 week, 1 month, 3 months, and 6 months post-intervention)
研究者
Ülkü Sabuncu
Assoc. Prof.
Ankara City Hospital Bilkent
