Chest Compression and Sustained Inflation
Not Applicable
Completed
- Conditions
- Newborn Infants Having Asystole or Bradycardia at Birth
- Interventions
- Procedure: CC+SI
- Registration Number
- NCT02083705
- Lead Sponsor
- University of Alberta
- Brief Summary
Guidelines on neonatal resuscitation recommend 90 chest compressions (CC) and 30 manual inflations (3:1) per minute in newborns. The study aimed to determine if CC s during sustained inflations (SI) improves recovery of asphyxiated newborns compared to coordinated 3:1 resuscitation.
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- COMPLETED
- Sex
- All
- Target Recruitment
- 9
Inclusion Criteria
Newborn infants with asystole Newborn infants with bradycardia
Exclusion Criteria
Study & Design
- Study Type
- INTERVENTIONAL
- Study Design
- SINGLE_GROUP
- Arm && Interventions
Group Intervention Description SI+CC CC+SI Chest compression will be superimposed by sustained inflations during CPR: "CC+SI group" Infants randomized in the SI group requiring CC, would receive CC at a rate of 90/min during an SI with a duration of 20sec (CC+SI). After 20 sec the SI will be interrupted for 1 sec and the next SI will be started for another 20sec13. Throughout this time CC is continued until ROSC. Every 45 sec (approximately 2 SIs) the clinical team would assess for changes in heart rate. CC+SI was continued until ROSC.
- Primary Outcome Measures
Name Time Method Time Needed to Achieve Return of Spontaneous Circulation within the first 10 minutes after birth We aim to reduce time needed to achieve Return of Spontaneous Circulation. This should be achieved by the experimental chest compression technique
- Secondary Outcome Measures
Name Time Method
Trial Locations
- Locations (1)
Royal Alexandra Hospital
🇨🇦Edmonton, Alberta, Canada