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Clinical Trials/NCT05596812
NCT05596812
Recruiting
N/A

A Novel Care Pathway in Women With "Low-risk" Gestational Diabetes Mellitus

Unity Health Toronto1 site in 1 country150 target enrollmentAugust 23, 2022

Overview

Phase
N/A
Intervention
Not specified
Conditions
Gestational Diabetes Mellitus in Pregnancy
Sponsor
Unity Health Toronto
Enrollment
150
Locations
1
Primary Endpoint
Feasibility of the novel risk stratification screening tool
Status
Recruiting
Last Updated
3 years ago

Overview

Brief Summary

This study is a randomized controlled trial to study the effect of the use of a risk stratification screening tool for high- and low-risk gestational diabetes mellitus (GDM), and the implementation of a new low-impact care pathway for women with low-risk GDM. The study will measure how well the screening tool and new care pathway are used, and the effect of the new low-impact care pathway on glycemic control, perinatal outcomes (large for gestational age, rate of labor induction, mode of delivery, obstetric anal sphincter injury, neonatal hypoglycemia, neonatal anthropometry) and health resource utilization in women with GDM that are at low-risk of dietary therapy failure.

Registry
clinicaltrials.gov
Start Date
August 23, 2022
End Date
August 2024
Last Updated
3 years ago
Study Type
Interventional
Study Design
Parallel
Sex
Female

Investigators

Responsible Party
Sponsor

Eligibility Criteria

Inclusion Criteria

  • Women able to understand and sign the study consent form
  • singleton pregnancy
  • planning to give birth to at St. Michael's Hospital
  • diagnosed with GDM between 24-32 weeks' gestation based on a positive GCT or GTT result as defined by the Canadian Diabetes Association Clinical Practice Guidelines

Exclusion Criteria

  • Women with preexisting diabetes (Type 1 or 2 diabetes)
  • multiple gestation, or a diagnosis of GDM before 24 weeks' or after 32 weeks' gestation
  • not continuing care at St. Michael's Hospital after the DIP clinic visit

Outcomes

Primary Outcomes

Feasibility of the novel risk stratification screening tool

Time Frame: 2 years

number of patients screened, recruited, consented and randomized as documented in the study recruitment log

Secondary Outcomes

  • Gestational weight gain(approximately 9 months (from recruitment at 24-32 weeks gestation to 3-months postpartum))
  • Development of hypertensive disorders of pregnancy(approximately 9 months (from recruitment at 24-32 weeks gestation to 3-months postpartum))
  • Delivery outcomes - mode of delivery(recorded at time of delivery)
  • Neonatal outcomes - Appearance, Pulse, Grimace, Activity, Respiration (APGAR) score(recorded at delivery (at 1 minute and 5 minutes of age))
  • Performance of the GDM risk stratification tool(2 years)
  • Glycemic control - blood glucose (units)(approximately 9 months (from recruitment at 24-32 weeks gestation to 3-months postpartum))
  • Glycemic control - blood glucose (percent above target)(approximately 9 months (from recruitment at 24-32 weeks gestation to 3-months postpartum))
  • Neonatal outcomes - size for gestational age(recorded at time of delivery)
  • Health service outcomes - Short-form Patient Satisfaction Questionnaire (PSQ-18)(2 years; administered to each participant at 6-weeks postpartum)
  • Delivery outcomes - gestational age at delivery(recorded at time of delivery)
  • Health service outcomes - health resource utilization(2 years)

Study Sites (1)

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