Exercise-Induced Hypoalgesia Differences at Proximal and Distal Regions After Applying a Lower Limb Resistance Training or an Upper Limb Resistance Training Protocol: A Randomized Controlled Trial in Healthy Participants
Overview
- Phase
- Not Applicable
- Intervention
- Not specified
- Conditions
- Local Hypoalgesia
- Sponsor
- Centro Universitario La Salle
- Enrollment
- 90
- Locations
- 1
- Primary Endpoint
- Pain pressure threshold (PPT) on dominant quadriceps and dominant brachial biceps
- Status
- Recruiting
- Last Updated
- last year
Overview
Brief Summary
This randomized controlled trial with healthy subjects aims to compare exercise-induced hypoalgesia among three groups: one utilizing a lower limb resistance training intervention, another using an upper limb resistance training, and a control group. The exercise protocol involves 3 sets of 5 repetitions of resistance exercises (brachial biceps curl and leg extensions). Exercise-induced hypoalgesia will be assessed by measuring pressure pain thresholds in the thigh and elbow, comparing exercise interventions with the control group. Additionally, a secondary objective is to compare the lower limb and upper limb resistance training groups in terms of their effects on pressure pain thresholds in the thigh and elbow. Thus, the study anticipates observing differences in local and distal hypoalgesia based on the trained region.
Investigators
Álvaro Reina Varona
Principal Investigator
Centro Universitario La Salle
Eligibility Criteria
Inclusion Criteria
- •Asymptomatic subjects aged between 18 and 64 years.
Exclusion Criteria
- •Cardiovascular, respiratory, metabolic, neurological, or osteomuscular signs or pathologies.
- •History of epilepsy.
- •Pregnant.
- •Participants who present any type of pain on the day of the measurements or who have frequently suffered pain during the previous 12 weeks.
Outcomes
Primary Outcomes
Pain pressure threshold (PPT) on dominant quadriceps and dominant brachial biceps
Time Frame: before, immediately after intervention, and 30 minutes after intervention.
PPT is tested on the muscle belly of the quadriceps on the dominant side, at half of the distance between the anterior-superior iliac spine and the superior pole of the patella, and on the muscle belly of the brachial biceps on the dominant side, at a point one-fourth of the distance from the elbow crease to the lateral border of the acromion. The region to be pressed is marked with a pen. The patient is instructed to report the first appearance of the sensation of "discomfort". An ascending ramp of 0.5 kg/cm/s is applied, at the rhythm of a metronome. The instrument measures 0 to 25 kg, with a higher score interpreted as a hypoalgesia response. The measurement is started on the quadriceps and alternated with the biceps until 3 measurements of each region are obtained. Each measurement in the same region is obtained after 30 seconds of rest. This protocol has demonstrated high inter-observer reliability measuring healthy subjects (ICC = 0.91).
Secondary Outcomes
- International Physical Activity Questionnaire (IPAQ)(before intervention (up 5 minutes))
- Physical Activity Readiness Questionnaire (PAR-Q)(before intervention (up 5 minutes))
- Fatigue Assessment Scale (FAS)(before intervention (up 5 minutes))
- Rate of perceived exertion (RPE)(immediately after intervention (up 10 seconds))