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Clinical Trials/NCT05781230
NCT05781230
Completed
Not Applicable

The Effect of Exercises of Different Intensity Applied After Total Knee Arthroplasty on Exercise-Induced Hypoalgesia: Randomised Controlled Trial

Hacettepe University1 site in 1 country38 target enrollmentJanuary 1, 2022

Overview

Phase
Not Applicable
Intervention
Not specified
Conditions
Knee Osteoarthritis
Sponsor
Hacettepe University
Enrollment
38
Locations
1
Primary Endpoint
Change of Pressure pain theshold
Status
Completed
Last Updated
3 years ago

Overview

Brief Summary

The aim of this study was to investigate whether exercise-induced hypoalgesia (EIH) is present following exercise in patient after total knee arthroplasty (TKA) and if so, if it changes with exercise intensity. A repeated measures and single-blinded randomized study were done. Thirty-eight patients 24 hours after TKA were randomly assigned to either low intensity exercises (LIE) group or high intensity exercises (HIE) group. An exercise programs lasted for five days during the hospitalization period. Pain severity was assessed by Visual Analog Scale (VAS) (0-10 mm). Pressure pain thresholds (PPTs) were measured over quadriceps and biceps brachii and muscles immediately before and after exercise.

Detailed Description

Background: The aim of this study was to investigate whether exercise-induced hypoalgesia (EIH) is present following exercise in patient after total knee arthroplasty (TKA) and if so, if it changes with exercise intensity. Methods : A repeated measures and single-blinded randomized study were done. Thirty-eight patients 24 hours after TKA were randomly assigned to either low intensity exercises (LIE) group or high intensity exercises (HIE) group. An exercise programs lasted for five days during the hospitalization period. Pain severity was assessed by Visual Analog Scale (VAS) (0-10 mm). Pressure pain thresholds (PPTs) were measured over quadriceps and biceps brachii and muscles immediately before and after exercise.

Registry
clinicaltrials.gov
Start Date
January 1, 2022
End Date
May 1, 2022
Last Updated
3 years ago
Study Type
Interventional
Study Design
Parallel
Sex
All

Investigators

Responsible Party
Principal Investigator
Principal Investigator

MERVE KARAPINAR

Assistant Professor

Hacettepe University

Eligibility Criteria

Inclusion Criteria

  • Patients had undergone primary unilateral total knee replacement surgery
  • Patients hospitalized for at least seven days were enrolled in this study.

Exclusion Criteria

  • Medically stable patients who used glucocorticoids or strong analgesic drugs
  • Patients had post-traumatic OA, rheumatoid arthritis (RA), psoriatic arthritis, cognitive, hearing and visual problems Patients were diagnosed chronic pain condition were excluded from the study.

Outcomes

Primary Outcomes

Change of Pressure pain theshold

Time Frame: admission to hospital service to discharge from hospital service, an average 5 days

Pressure pain threshold (PPTs) were assessed using a handheld pressure algo-meter

change of pain severity

Time Frame: admission to hospital service to discharge from hospital service, an average 5 days

. The pain severity evaluated using a visual analogue scale (VAS; scored from 0, no pain, to 100, the worst pain ever).

Study Sites (1)

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