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临床试验/NCT05525403
NCT05525403已完成不适用

The Effects of Fatigue on Exercise-Induced Hypoalgesia During a Dynamic Resistance Exercise

University of Central Florida2 个研究点 分布在 1 个国家目标入组 31 人开始时间: 2022年10月28日最近更新:
适应症

试验速览

阶段
不适用
状态
已完成
入组人数
31
试验地点
2
主要终点
Change in Pressure Pain Threshold

研究概览

简要总结

The primary purpose of this study is to compare immediate changes in pain sensitivity (pressure pain threshold) during quiet rest, low fatigue exercise, and high fatigue exercise.

详细描述

Participants will attend three sessions. Participants will fill out questionnaires, undergo pain sensitivity testing, and be randomly assigned to complete a high and low fatigue exercise on either the second or third session. During the exercise, participants will complete three sets of a single leg knee extension exercise with weight equivalent to 50% of their 1 repetition maximum until they report either a high or low fatigue level. Immediately before and after each set, the research team will examine immediate changes in sensitivity to pressure (pressure pain threshold).

研究设计

研究类型
Interventional
分配方式
Randomized
干预模型
Crossover
主要目的
Treatment
盲法
None

入排标准

年龄范围
18 Years 至 60 Years(Adult)
性别
All
接受健康志愿者

入选标准

  • Pain-free
  • 18-60 years old
  • Participant can appropriately perform the knee extension exercise (assessed during screening)

排除标准

  • Non-English speaking
  • Regular use of prescription pain medications
  • Current or history of chronic pain condition
  • Currently taking blood-thinning medication
  • Systemic medical condition known to affect sensation, such as uncontrolled diabetes or neurological conditions
  • Any contraindication to the application of ice, such as: uncontrolled hypertension (blood pressure over 140/90 mmHg), cold urticaria, cryoglobulinemia, paroxysmal cold hemoglobinuria, circulatory compromise
  • Known presence of cardiovascular, pulmonary, or metabolic disease
  • Current use of tobacco products
  • Not physically ready to exercise without a medical exam as indicated by the Physical Activity Readiness Questionnaire Plus (PAR-Q+)
  • Surgery, injury, or fracture to the lower back or lower extremity within the past 6 months

结局指标

主要结局

Change in Pressure Pain Threshold

时间窗: Change from baseline immediately after exercise

A digital pressure algometer will be applied to the quadriceps and upper trapezius for two trials each. Participants are instructed to say "stop" or "pain" so the stimulus can be terminated "when the sensation first transitions from pressure to pain" (pain threshold). Participants will rate the pain experienced during the threshold testing using a 101-point numeric pain rate scale (NPRS) anchored with 0= no pain to 100= the most intense pain sensation imaginable immediately following each testing time.

次要结局

  • International Physical Activity Questionnaire Short Form(Baseline, pre exercise)
  • Pittsburgh Sleep Quality Index(Baseline, pre exercise)
  • Brief Resilience Scale(Baseline, pre exercise)
  • Heat Pain Threshold(Baseline, pre exercise)
  • Pain Anxiety Symptom Scale(Baseline, pre exercise)
  • Fear of Pain Questionnaire 9(Baseline, pre exercise)
  • Preference for and Tolerance of the Intensity of Exercise Questionnaire(Baseline, pre exercise)
  • Temporal Summation(Baseline, pre exercise)
  • Conditioned Pain Modulation(Baseline, pre exercise)
  • Pain Catastrophizing Scale(Baseline, pre exercise)

研究者

申办方类型
Other
责任方
Principal Investigator
主要研究者

Abigail Wilson

Assistant Professor

University of Central Florida

研究点 (2)

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