Recession Coverage Using Modified Coronally Advanced Tunnel(MCAT)
- Conditions
- Gingival Recession
- Interventions
- Procedure: MCAT + subepithelial connective tissue graftProcedure: MCAT + enamel matrix derivateProcedure: MCAT + subepithelial connective tissue graft + enamel matrix derivative
- Registration Number
- NCT06504329
- Lead Sponsor
- Necmettin Erbakan University
- Brief Summary
In our study, patients with Miller Class I and II gingival recession will be divided into three groups to undergo the modified coronally advanced tunnel (MCAT) technique using connective tissue grafts, enamel matrix derivatives, or a combination of connective tissue grafts and enamel matrix derivatives. The short- and long-term success of these groups will be evaluated. There are limited studies on the MCAT technique in the literature, and our objectives and anticipated outcomes upon completion of the project are as follows:
1. Evaluation of the success of the MCAT technique in root coverage.
2. Evaluation of the aesthetic outcomes of the MCAT technique.
3. Evaluation of the impact of the MCAT technique on postoperative patient comfort and morbidity.
4. Assessment of the effect of enamel matrix derivative (Emdogain) application on treatment outcomes.
5. Assessment of the effect of connective tissue graft on treatment outcomes.
6. Investigation of the additional benefits of combining connective tissue grafts with enamel matrix derivatives.
7. Evaluation of the long-term outcomes of gingival recession treatment.
By focusing on these goals, the investigators aim to provide comprehensive insights into the efficacy and benefits of the MCAT technique and its variations in treating gingival recession.
- Detailed Description
This study is planned to be conducted with 60 individuals, aged between 18 and 45, who have presented to the Department of Periodontology at Necmettin Erbakan University Faculty of Dentistry for various reasons. Routine initial periodontal examinations and Phase 1 periodontal treatments will be performed on individuals exhibiting gingival recession and associated sensitivity. Standard mucogingival surgical procedures are routinely applied in our faculty to these individuals.
In our study, the short- and long-term outcomes of the MCAT technique, a mucogingival approach, will be evaluated. The study will consist of the following three groups:
Group 1: Modified coronally advanced tunnel (MCAT) + subepithelial connective tissue graft (n:20) Group 2: Modified coronally advanced tunnel (MCAT) + enamel matrix derivative(n:20) Group 3: Modified coronally advanced tunnel (MCAT) + subepithelial connective tissue graft + enamel matrix derivative(n:20)
Our study is designed as a randomized, controlled clinical trial. Measurements will include gingival thickness, the amount of root coverage, and keratinized gingiva parameters, recorded using a Williams probe (Hu-Friedy) and rounded to the nearest millimeter.
For gingival recession, plaque index, and gingival index will be obtained from three points: mesial, distal, and midpoints. The plaque index will be calculated according to the criteria defined by Silness and Loe, while the gingival index will be assessed based on the criteria defined by Loe and Silness. Gingival thickness will be measured 3 mm below the gingival margin under topical anesthesia using an endodontic reamer with a stopper.
Patients will be asked to complete a chart rating their subjective pain, burning sensation, and discomfort in the surgical area on a visual analogue scale (VAS) ranging from 0 (none) to 100 (very severe) on postoperative days 3 and 7. The clinician will remove the sutures two weeks after surgery and will complete the wound healing index for each tooth individually according to Huang's criteria.
This study aims to provide comprehensive insights into the effectiveness and benefits of the MCAT technique and its variations in treating gingival recession.
Recruitment & Eligibility
- Status
- RECRUITING
- Sex
- All
- Target Recruitment
- 60
- Volunteers aged between 18-45 years.
- No previous surgical procedures should have been performed in the selected areas.
- Presence of periodontal pockets not exceeding 3 mm in treated teeth; absence of occlusal trauma.
- Not being pregnant or breastfeeding, and not undergoing any regulatory drug treatment.
- Patients presenting with various periodontal problems who have received indications for modified coronally advanced tunnel due to gingival recession in the periodontology clinic.
- Absence of any systemic condition that could interfere with surgical procedures.
- Exclusion criteria and refusal to participate in the study.
Study & Design
- Study Type
- INTERVENTIONAL
- Study Design
- SEQUENTIAL
- Arm && Interventions
Group Intervention Description MCAT + subepithelial connective tissue graft MCAT + subepithelial connective tissue graft In this group, participants will undergo the modified coronally advanced tunnel (MCAT) technique, and a subepithelial connective tissue graft will be placed. MCAT + enamel matrix derivative MCAT + enamel matrix derivate In this group, participants will undergo the modified coronally advanced tunnel (MCAT) technique, and Emdogain (0.15 ml gel form) will be applied. Emdogain will be used as an enamel matrix derivative. MCAT + subepithelial connective tissue graft + enamel matrix derivative MCAT + subepithelial connective tissue graft + enamel matrix derivative In this group, participants will undergo the modified coronally advanced tunnel (MCAT) technique, a subepithelial connective tissue graft will be placed, and an enamel matrix derivative(Emdogain -0.15 ml gel form) will be applied.
- Primary Outcome Measures
Name Time Method Measurement of Preoperative Periodontal Parameters and Taking Initial Photographs Preoperatively, before the start of treatment. To determine the baseline condition, pre-surgical measurement of periodontal parameters (amount of keratinized tissue, papilla height, papilla width, probing pocket depth, amount of recession) will be recorded in millimeters using a periodontal probe.Plaque Index (PI) (Silness and Löe 1964) and Gingival Index (GI) (Löe and Silness 1963) will be scored on a scale of 0-3. Additionally, intraoral photographs of the patients will be taken prior to the operation. This is necessary to document the pre-treatment condition and evaluate changes post-treatment.
- Secondary Outcome Measures
Name Time Method Measurement of Periodontal Parameters and Taking Photographs at 1, 3, and 6 Months Post-Operation 1, 3, and 6 months post-operation. Postoperative measurement of periodontal parameters will be recorded using a periodontal probe in millimeters at 1, 3, and 6 months. The parameters include the amount of keratinized tissue, papilla height, papilla width, probing pocket depth and the amount of recession.Plaque Index (PI) (Silness and Löe 1964) and Gingival Index (GI) (Löe and Silness 1963) will be scored on a scale of 0-3. Additionally, intraoral photographs of the patients will be taken. This is necessary to evaluate changes following treatment.
Trial Locations
- Locations (1)
Necmettin Erbakan University, Faculty of Dentistry
🇹🇷Konya, Turkey