The Effect of Low Dose Ketamine on Narcotic Consumption in Patients Undergoing Laparoscopic Cholecystectomy
- Registration Number
- NCT05444777
- Lead Sponsor
- Aga Khan University
- Brief Summary
This double-blinded randomized control trial aims to analyze the effect of low dose Ketamine on narcotic consumption, in patients undergoing Laparoscopic cholecystectomy.
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- COMPLETED
- Sex
- All
- Target Recruitment
- 86
Inclusion Criteria
- all ASA 1 and 2 patients undergoing Laparoscopic Cholecystectomy electively.
Exclusion Criteria
- Hepatic and renal disease and ASA 3 and 4 patients.
Study & Design
- Study Type
- INTERVENTIONAL
- Study Design
- PARALLEL
- Arm && Interventions
Group Intervention Description Saline group (Group S) Ketamine Hydrochloride Group S was given saline in 10 ml syringe Ketamine group (Group K) Ketamine Hydrochloride Group K was given ketamine @ 0.5mg/kg (prepared by dilution in 0.9% normal saline in 10 ml syringe) at the time of wound closure.
- Primary Outcome Measures
Name Time Method pain score using Visual Analogue scale, ranging from 0 (minimum) and 10 (maximum), 3 and below showing no pain and scores above 3 showing moderate to severe pain. Baseline on arrival in the post anaesthesia care unit and then every fifteen minutes unto one hour Change in pain score using Visual Analogue Scale
- Secondary Outcome Measures
Name Time Method narcotic consumption in the post operative anaesthesia care unit postoperatively, after arrival in the post anaesthesia care unit at every fifteen minutes unto one hour requirement of narcotic in the post anaesthesia care unit