CTRI/2019/08/021000招募中未知
Efficacy and Safety of Testosterone Therapy in Improving Sarcopenia in Men With Cirrhosis a Randomized Controlled Trial
试验速览
- 阶段
- 未知
- 状态
- 招募中
研究概览
简要总结
暂无简介。
研究设计
- 研究类型
- Interventional
入排标准
入选标准
- •1) Men with cirrhosis of any etiology
- •2) Sarcopenia
- •3) CTP 6-12
排除标准
- •1) Hepatocellular carcinoma
- •2) Other known malignancy,
- •3) CTP > 12
- •4) Acute liver injury
- •5) Prostate disease,
- •6) Known hypersensitivity to testosterone therapy,
- •Polycythaemia (haematocrit >55%),
- •7) Uncontrolled hypertension ( >160/90 mmHg despite treatment),
- •8) Uncontrolled obstructive sleep apnoea,
- •9) Severe renal dysfunction (estimated glomerular filtration rate <30ml/min)
- •10) Uncontrolled epilepsy, migraine, or significant cardiac insufficiency (New York Heart Association class III or IV or LVEF < 45-50%.
- •11) CKD (Chronic Kidney Disease) - eGFR (Glomerular Filtration Rate) <60%
- •12) Platelet count below 30,000 or taking warfarin
- •13) Failure to give consent.
研究者
相似试验
进行中（未招募）
1 期
Does Testposterone improve the Pain Perception of Patients with Chronic Pain?Patient with persistent somatoform pain disorder (F45.40 or F45.41) should be included into the study.EUCTR2016-000048-32-DERWTH Aachen University/CTC-A60
已完成
3 期
Effect of Testosterone Therapy Combined with Very Low Caloric Diet on Weight Loss and Weight Maintenance in Obese Men: A Randomized Controlled TrialObesityACTRN12613000613707niversity of Melbourne100
已完成
4 期
A clinical trial to study the effect of two drugs, triamcinolone and methylprednisolone injection in patients with capillary hemangioma (malformation of blood vessels)CTRI/2011/11/002169Post Graduate Institute of Medical Education and Research16
进行中（未招募）
不适用
Effect of Transdermal Testosterone Replacement in Hypogonadal Men with either Metabolic Syndrome or Type 2 Diabetes Mellitus - TIMES 2Male hypogonadism is generally characterised by abnormally low serum testosterone levels. Symptoms include changes in mood, decreased bone mineral density, increased body fat, decreased muscle mass and strength and sexual dysfunction. A number of conditions can also be associated with decreased testosterone production including metabolic syndrome, type II diabetes mellitus, atherosclerosis, myocardial infarction and chronic heart failureEUCTR2005-002607-17-DEProstrakan Pharmaceuticals Ltd520
进行中（未招募）
不适用
Effect of Transdermal Testosterone Replacement in Hypogonadal Men with either Metabolic Syndrome or Type 2 Diabetes MellitusEUCTR2005-002607-17-ITSTRAKAN PHARMACEUTICALS LIMITED320