Bronchiectasis Effect in COPD Patients

Completed

• Conditions: Copd; Bronchiectasis

• Registration Number: NCT03670940
• Lead Sponsor: Izmir Katip Celebi University

Brief Summary

The etiology of bronchiectasis, known as permanent, abnormal, and localized development of bronchi, varies. However, most of them are responsible for infections during childhood. The prevalence of bronchiectasis is particularly high in advanced COPD patients. This phenomenon, called COPD-bronchiectasis overlap syndrome, affects the clinic of COPD patients negatively. In this study; bronchiectasis in respiratory function, exercise capacity, dyspnoea and quality of life in COPD patients.

Detailed Description

The etiology of bronchiectasis, known as permanent, abnormal, and localized development of bronchi, varies. However, most of them are responsible for infections during childhood. The prevalence of bronchiectasis is particularly high in advanced COPD patients. This phenomenon, called COPD-bronchiectasis overlap syndrome, affects the clinic of COPD patients negatively. In this study; bronchiectasis in respiratory function, exercise capacity, dyspnoea and quality of life in COPD patients.

Torax CTs of patients with COPD who are admitted to the outpatient clinic will be examined. There will be two groups, group 1 in patients with COPD accompanied by bronchiectasis and group 2 in COPD patients without bronchiectasis. In both groups, respiratory function tests, exercise capacities, dyspnea perceptions and quality of life will be evaluated. The data will be compared between the two groups.

Study Timeline

• Study Start: 2015-01
• Primary Completion: 2018-03
• Study Completion: 2018-04
• Status Verified: 2018-09
• Study First Submitted: 2018-09-12
• Study First Submitted QC: 2018-09-13
• Last Update Submitted: 2018-09-13
• Study First Posted: 2018-09-14
• Last Update Posted: 2018-09-14

Recruitment & Eligibility

• Status: COMPLETED
• Sex: All
• Target Recruitment: 35

Inclusion Criteria

• above 18 years old
• clinically stable

Exclusion Criteria

• other respiratory disease

Study & Design

• Study Type: OBSERVATIONAL
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Exercise capacity	15 minutes	six minute walk test

Secondary Outcome Measures

Name	Time	Method
Dyspnea Severity	5 minutes	mMRC Dyspnea Scale (0: no dyspnea, 4: very severe dyspnea)
Lung Function	20 minutes	Respiratory Function Test
Health Related Quality of Life	25 minutes	St. George Respiratory Questionnaire (maximum score: 100, lower score means better quality of life)