The Effect of Bronchiectasis on the Exacerbation and Mortality of Chronic Obstructive Pulmonary Disease
Overview
- Phase
- Not Applicable
- Intervention
- Not specified
- Conditions
- Bronchiectasis
- Sponsor
- Ministry of Health, Turkey
- Enrollment
- 122
- Primary Endpoint
- Charlson Comorbidity Index
- Status
- Completed
- Last Updated
- 6 years ago
Overview
Brief Summary
Chronic obstructive pulmonary disease (COPD) is a chronic inflammatory disease of the airways and lungs that develops against harmful particles or gases with exacerbations. Coexistence of bronchiectasis with COPD may lead to worsening of the functional parameters as well as alteration of the microbiological pattern in exacerbations and may negatively affect the exacerbation result parameters.
Detailed Description
Chronic obstructive pulmonary disease (COPD) is a chronic inflammatory disease of the airways and lungs that develops against harmful particles or gases with exacerbations. COPD exacerbations are characterized by worsening of dyspnea, coughing and expectoration. Exacerbations requiring hospitalization are the main cause of morbidity and mortality in COPD. Bronchiectasis is the irreversible extension of the bronchi. Usually follows with chronic sputum cough, airway obstruction and recurrent infection episodes. The association of bronchiectasis and COPD has long been known and its incidence is in the range of 30-50%. Coexistence of bronchiectasis with COPD may lead to worsening of the functional parameters as well as alteration of the microbiological pattern in exacerbations and may negatively affect the exacerbation result parameters.
Investigators
Zeynep FENDOGLU
Principal investigator
Ministry of Health, Turkey
Eligibility Criteria
Inclusion Criteria
- •Patients who underwent thoracic tomography in the last year according to index exacerbation date were included in the study
Exclusion Criteria
- •Cases that mimic COPD exacerbation (pneumonia, pulmonary thromboembolism, pulmonary congestion, pneumothorax, pleural effusion, lung malignancy, asthma, asthma-COPD overlap syndrome) and patients admitted to the intensive care unit were excluded from the study.
Outcomes
Primary Outcomes
Charlson Comorbidity Index
Time Frame: 1 hour
Comorbidity scores
Secondary Outcomes
- Spirometry(1 hour)