Comparison of the efficacy of intramuscular versus intravenous combined Ketamine and Dexmedetomidine for sedation in Pediatric patients undergoing MRI: A prospective randomized comparative clinical study.
试验速览
- 阶段
- Unknown
- 状态
- Not Applicable
- 发起方
- 入组人数
- 104
- 试验地点
- 1
- 主要终点
- To compare the quality of sedation acheived by intamuscular versus intravenous injection ketamine and inj dexmedetomidine combination in peadiatric patients undergoing MRI as assessed by image quality
研究概览
简要总结
EFFICACY OF COMBINED INJ KETAMINE AND INJ DEXMEDETOMIDINE INTRAVENOUSLY VERSUS INTRAMUSCULARLY FOR SEDATION IN PEADIATRIC PATIENTS UNDERGOING MRI
Dose of drugs used intravenously
Inj ketamine 0.5 - 1 mg/kg and Inj dexmedetomidine 0.3 -0.5 microgram/kg
Dose of drugs used intramuscularly
Inj ketamine 3 - 4mg/kg and Inj Dexmedetomidine 1 -1.5 microgram/kg
In both the groups Ramsay sedation score 5 would be achieved
In both the groups maintainance dose of inj ketamine 0.5mg/kg is intravenously if the patient moves or MRI scan shows any motion artifect
Recovery profile will be accessed by Modified Alderate score if 9 or more than 9
Hemodynamic stablity and adverse effects are monitored
研究设计
- 研究类型
- Observational
入排标准
- 年龄范围
- 6.00 Month(s) 至 8.00 Year(s)（—）
- 性别
- All
入选标准
- •Age group 6months to 8 years of either gender Patients with ASA I-II-III status Scheduleded to undergo MRI with time less than 60 mins Able to provide written informed consent by relatives.
排除标准
- •Not able to provide written informed consent by relatives Hypersensitivity to drugs used in the study Presence of congenital heart diseases and pulmonary diseases Recent upper respiratory tract infections or pneumonia Facial malformation and anticipatory difficult intubation Extreme tonsillar hypertrophy Raised intracranial tension.
结局指标
主要结局
To compare the quality of sedation acheived by intamuscular versus intravenous injection ketamine and inj dexmedetomidine combination in peadiatric patients undergoing MRI as assessed by image quality
时间窗: 3 hours
次要结局
- Hemodynamic stablity heart rate and oxygen saturation(Duration of MRI scan and number of rescue bolus required)
研究者
Dr Rina B Gameti
Government Medical College Vadodara