Behavioral and Neurophysiological Effects of Multichannel Executive Network tDCS Combined With Preferred Music Stimulation

Phase 1

Completed

• Conditions: Healthy
• Interventions: Device: tDCS; Device: Sham tDCS; Other: White noise; Other: Music

• Registration Number: NCT04705532
• Lead Sponsor: University of Liege

Brief Summary

This study aims at comparing the effects of transcranial direct current stimulation combined with music on neurophysiological outcomes in healthy participants. This study also aims to evaluate the effects of tDCS combined with music on cognition.

Detailed Description

Not available

Study Timeline

• Study Start: 2019-10-04
• Study First Submitted: 2021-01-07
• Study First Submitted QC: 2021-01-09
• Study First Posted: 2021-01-12
• Primary Completion: 2021-12-30
• Study Completion: 2021-12-30
• Status Verified: 2024-08
• Last Update Submitted: 2024-08-02
• Last Update Posted: 2024-08-05

Recruitment & Eligibility

• Status: COMPLETED
• Sex: All
• Target Recruitment: 24

Inclusion Criteria

• healthy adults

Exclusion Criteria

• neurological disorders
• psychiatric disorders
• contra-indication to tDCS (eg, metallic brain implant, pacemaker)
• pregnancy
• alcool abuse
• active smoker

Study & Design

• Study Type: INTERVENTIONAL
• Study Design: CROSSOVER

Arm && Interventions

Group	Intervention	Description
tDCS/white noise	tDCS	active tDCS combined with white noise
sham tDCS/white noise	White noise	sham tDCS combined with white noise
tDCS/music	tDCS	active tDCS combined with music
tDCS/music	Music	active tDCS combined with music
sham tDCS/music	Music	Sham tDCS combined with music
sham tDCS/white noise	Sham tDCS	sham tDCS combined with white noise
sham tDCS/music	Sham tDCS	Sham tDCS combined with music
tDCS/white noise	White noise	active tDCS combined with white noise

Primary Outcome Measures

Name	Time	Method
3-back	It will be measured over the course of four weeks	The subject is presented with a sequence of stimuli, and the task consists of indicating when the current stimulus matches the one from 3 steps earlier in the sequence.

Secondary Outcome Measures

Name	Time	Method
EEG - alpha power	It will be measured over the course of four weeks	Brain activity will be measured with an electroencephalography collected at rest. We will first look at the change in alpha power (8-12Hz)
Stroop	It will be measured over the course of four weeks	The subject has to name the font color of a printed word, while it can have a mismatch between the word and the color (ex: green is written in red).
EEG - beta power	It will be measured over the course of four weeks	Brain activity will be measured with an electroencephalography collected at rest. We will also look at the change in other frequency bands (e.g., beta, theta, delta).

Trial Locations

Locations (1)

University Hospital of Liege; 🇧🇪 Liege, Belgium