A comparative study on the postoperative recovery between balanced and total intravenous anesthesia in patients undergoing off-pump coronary artery bypass surgery
Overview
- Phase
- 未知
- Intervention
- Not specified
- Conditions
- Diseases of the circulatory system
- Sponsor
- Chonnam National University Hospital
- Enrollment
- 102
- Status
- Completed
- Last Updated
- 3 years ago
Overview
Brief Summary
Background: Recovery after anesthesia is known to have a significant impact on the patient's return to daily life. But studies on the difference of recovery from anesthesia according to the anesthetic method have not yet been conducted at off-pump coronary artery bypass graft surgery (OPCAB). The purpose of this study was to investigate the difference in the postoperative quality of recovery according to the anesthetic method in patients undergoing OPCAB using quality of recovery – 40 (QoR-40K). Methods: This prospective, randomized, single-blind, controlled study was performed on 102 patients undergoing OPCAB under general anesthesia. The patients were randomly assigned to one of two groups, the total intravenous anesthesia group (Group T) and the balanced anesthesia group (Group B) using sevoflurane. QoR-40K score was measured at preoperative, extubation after 24hr and 48hr. Results: There was no difference in the QoR-40kK score at 24 hours after extubation according to the anesthetic method in patients undergoing OPCAB surgery. Also, there was no statistical difference in QoR-40K scores between the two groups at 48 hours after extubation and there was no significant difference in five dimensions of QoR-40k at 24, 48 hours. Conclusions: In this study, there was no difference in QoR-40K scores at 24 hours after extubation between the total intravenous anesthesia group and the balanced anesthesia group in recovery from anesthesia in OPCAB surgery. Therefore, it is considered that both anesthetic methods using inhalation anesthetics or intravenous anesthetics can be used in OPCAB.
Investigators
Eligibility Criteria
Inclusion Criteria
- •Patients who are American sociaty of anesthesiologist physical status I, II, III, IV
- •Patients aged 20–80 year
- •Patients Undergoing Coronary Artery Bypass Surgery under general anesthesia
- •Patients who have voluntarily agreed to participate in this study
Exclusion Criteria
- •Patients who have taken sleeping pills, antipsychotics or narcotic analgesics for more than 1 week
- •Patient who had mental retardation
- •Patient with iliteracy
- •Conversion to on\-pump coronary artery bypass surgery
- •Patients with left ventricular ejection fraction less than 30%
- •Major organ failure before surgery (plasma creatine more than 2 mg/dL, AST / ALT with greater than three times normal elevations, with persistent elevations, neurological abnormalities)
- •Patients who continue to need mechanical ventilation after surgery
Outcomes
Primary Outcomes
Not specified