Comparison of Quality of Recovery Between Remimazolam and Propofol Anesthesia in Patients Undergoing Arthroscopic Meniscectomy
Overview
- Phase
- Not Applicable
- Intervention
- Propofol TIVA
- Conditions
- Adult Patients 19 or Older Scheduled for Elective Arthroscopic Meniscectomy
- Sponsor
- Yonsei University
- Enrollment
- 80
- Locations
- 1
- Primary Endpoint
- Quality of Recovery (QoR)-40 questionnaire
- Status
- Completed
- Last Updated
- last year
Overview
Brief Summary
This study aims to compare quality of recovery after surgery and anesthesia between patients undergoing arthroscopic meniscectomy under general anesthesia with either propofol or remimazolam based total intravenous anesthesia. This study is a randomized trial with a 50% probability of being assigned to either group. Randomization will be done by an anesthesiologist not involved in anesthesia or postoperative outcome assessment. Patients and the investigator in charge of postoperative outcomes assessment will be blinded to group allocation.
Investigators
Eligibility Criteria
Inclusion Criteria
- •Adult patients 19 or older, ASA class I\~III,
- •scheduled for arthroscopic meniscectomy under general anesthesia and eligible for LMA use.
Exclusion Criteria
- •Patient refusal,
- •patients unable to read consent form, active URI or uncontrolled asthma,
- •pneumonia,
- •history of allergies to propofol or benzodiazepines,
- •decreased liver or kidney function, heart failure of ejection fraction\<55%,
- •pregnant or breastfeeding patients,
- •history of substance abuse/addiction
Arms & Interventions
Propofol
Patients receiving general anesthesia with propofol-based total intravenous anesthesia
Intervention: Propofol TIVA
Remimazolam
Patients receiving general anesthesia with remimazolam-based total intravenous anesthesia
Intervention: Remimazolam TIVA
Outcomes
Primary Outcomes
Quality of Recovery (QoR)-40 questionnaire
Time Frame: Postoperative 24 hours
Quality of recovery assessed with the QoR-40 questionnaire, which is a widely-used, self-rated, self-completed questionnaire for postoperative patients.