investigation of the effect of propranolol on sympathetic skin response and bone mass density of burn patients

Shiraz University of Medical Sciences0 个研究点目标入组 200 人开始时间: 待定最近更新: 2018年2月22日

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•We will include 18 to 50 years old patients experiencing electrical injury 15 days to 3 months prior to the study. Exclusion criteria are as follows: positive history of joint or bone disease; neuropathy (central or peripheral); diabetes mellitus or consumption of any drug affecting the autonomic nervous system; any cast; skin lesion, skin graft, or scar at the sites of SSR recording or stimulus (palms, soles, wrists, or ankles) that make technical problems for SSR recording; contraindications of propranolol administration such as bronchial asthma, pronounced bradycardia, manifest heart failure, second and third degree heart block, hypersensitivity to propranolol. Any patient with evidence of peripheral neuropathy on 4 limb electrophysiologic study (done at the beginning of the study after filling in the written informed consent).

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