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Clinical Trials/NCT06632301
NCT06632301
Not Yet Recruiting
N/A

DEXA Bone Density Analysis to Analyze the Loading Concept of the CoreHip® Prosthesis

Aesculap AG1 site in 1 country40 target enrollmentDecember 1, 2025

Overview

Phase
N/A
Intervention
Not specified
Conditions
Primary Osteoarthritis
Sponsor
Aesculap AG
Enrollment
40
Locations
1
Primary Endpoint
Radiological changes in the diaphyseal bone density (Gruen Zones 3 and 4)
Status
Not Yet Recruiting
Last Updated
8 months ago

Overview

Brief Summary

The goal of this interventional post-market follow-up study is to evaluate radiological changes in the diaphyseal bone density (Gruen Zones 3 and 4) within 24 months postoperative in patients treated with CoreHip® primary cementless stem. The DEXA bone density analysis is used.

Detailed Description

Additional diagnostic examination: DEXA-Analysis. A DEXA scan is an imaging test that measures bone density (strength). The results can provide helpful details about risk for osteoporosis (bone loss) and fractures. Furthermore we would like to find out more about stress shielding processes around our prosthesis.

Registry
clinicaltrials.gov
Start Date
December 1, 2025
End Date
May 1, 2027
Last Updated
8 months ago
Study Type
Interventional
Study Design
Single Group
Sex
All

Investigators

Responsible Party
Sponsor

Eligibility Criteria

Inclusion Criteria

  • Unilateral hip osteoarthritis
  • Indication for CoreHip Standard hip stem according to preoperative planning
  • Written Informed Consent
  • Age 35-85 years
  • According to the assessment of the study doctor, the patient is therapy compliant and able to attend the follow-up visits

Exclusion Criteria

  • Femoral neck fractures
  • Pregnancy
  • BMI \> 35
  • History of femoral fracture or previous surgery on the same hip
  • Metabolic bone disease, use of steroids or other drugs affecting bone metabolism
  • Intraoperative bone cracks
  • Severe osteoarthritis of the contralateral hip
  • THA of the contralateral side or other event leading to restricted weight bearing during the study period

Outcomes

Primary Outcomes

Radiological changes in the diaphyseal bone density (Gruen Zones 3 and 4)

Time Frame: within 24 months postoperative

Changes in bone mineral density (BMD) according to Gruen.

Secondary Outcomes

  • Development of Forgotten Joint Score(preoperative, at discharge (1 week postop) and 12 months postoperative)
  • Clinical Results: Joint Function (Harris Hip Score)(preoperative, at discharge (1 week postop) and 12 months postoperative)
  • Development of Quality of Life (EQ-5D-5L)(preoperative, at discharge (1 week postop) and 12 months postoperative)
  • Development of Pain(preoperative, at discharge (1 week postop) and 12 months postoperative)

Study Sites (1)

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