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Clinical Trials/NCT01066936
NCT01066936
Completed
Not Applicable

Bone Density by Dual Energy X-ray Absorptiometry (DEXA) Following Total Hip Arthroplasty With the "Short Mini Stem"

Smith & Nephew, Inc.1 site in 1 country20 target enrollmentSeptember 14, 2009

Overview

Phase
Not Applicable
Intervention
Not specified
Conditions
Osteoarthritis, Hip
Sponsor
Smith & Nephew, Inc.
Enrollment
20
Locations
1
Primary Endpoint
DEXA Analysis of BMD at Preoperative Visit
Status
Completed
Last Updated
6 years ago

Overview

Brief Summary

The objective of this study is to evaluate the bone ingrowth after implantation of the study device. This study will also document any device-related surgical complications or adverse radiographic observations. Improvement in pain, function, and health economic data will be compared with improvements documented with other joint systems.

Detailed Description

The purpose of the current investigation is to assess the bone ingrowth after implantation with a modular, short hip stem using Dual Energy X-ray Absorptiometry (DEXA). The intended use of this product is for patients with non-inflammatory and inflammatory degenerative joint disease who require a primary total hip replacement.

Registry
clinicaltrials.gov
Start Date
September 14, 2009
End Date
April 18, 2016
Last Updated
6 years ago
Study Type
Observational
Sex
All

Investigators

Responsible Party
Sponsor

Eligibility Criteria

Inclusion Criteria

  • Patient has hip disease that requires a total hip arthroplasty.
  • Patient is willing to consent to participate in the study.
  • Patient plans to be available for the study duration.
  • Patient is in stable health and is free of or treated and stabilized for cardiac, pulmonary, hematological, or other conditions that would pose excessive operative risk.

Exclusion Criteria

  • Patient known to have insufficient bone stock.
  • Patient has had major non-arthroscopic surgery to the study hip.
  • Patient has physical, emotional or neurological conditions that would compromise the patient's compliance with postoperative rehabilitation and follow-up.
  • Patient has a known sensitivity to materials in the device.

Outcomes

Primary Outcomes

DEXA Analysis of BMD at Preoperative Visit

Time Frame: Preoperative

DEXA=Dual Energy X-Ray Absorptiometry; BMD=Bone Mineral Density; The proximal femur was divided into 7 regions relative to the length of the stem. Lateral portions = region 1, region 2 and region 3; The entire bone mass immediately distal to the stem tip = region 4; Medial portions = region 5, region 6, and region 7. Mean BMD was calculated for each femoral region. BMD values were adjusted peri-prosthetically to account for stem area.

DEXA Analysis of BMD at 6 Months

Time Frame: 6 Months

DEXA=Dual Energy X-Ray Absorptiometry; BMD=Bone Mineral Density; The proximal femur was divided into 7 regions relative to the length of the stem. Lateral portions = region 1, region 2 and region 3; The entire bone mass immediately distal to the stem tip = region 4; Medial portions = region 5, region 6, and region 7. Mean BMD was calculated for each femoral region. BMD values were adjusted peri-prosthetically to account for stem area.

DEXA Analysis of BMD at 1 Year

Time Frame: 1 Year

DEXA=Dual Energy X-Ray Absorptiometry; BMD=Bone Mineral Density; The proximal femur was divided into 7 regions relative to the length of the stem. Lateral portions = region 1, region 2 and region 3; The entire bone mass immediately distal to the stem tip = region 4; Medial portions = region 5, region 6, and region 7. Mean BMD was calculated for each femoral region. BMD values were adjusted peri-prosthetically to account for stem area.

DEXA Analysis of BMD at 2 Years

Time Frame: 2 Year

DEXA=Dual Energy X-Ray Absorptiometry; BMD=Bone Mineral Density; The proximal femur was divided into 7 regions relative to the length of the stem. Lateral portions = region 1, region 2 and region 3; The entire bone mass immediately distal to the stem tip = region 4; Medial portions = region 5, region 6, and region 7. Mean BMD was calculated for each femoral region. BMD values were adjusted peri-prosthetically to account for stem area.

DEXA Analysis of BMD at 3 Months

Time Frame: 3 Months

DEXA=Dual Energy X-Ray Absorptiometry; BMD=Bone Mineral Density; The proximal femur was divided into 7 regions relative to the length of the stem. Lateral portions = region 1, region 2 and region 3; The entire bone mass immediately distal to the stem tip = region 4; Medial portions = region 5, region 6, and region 7. Mean BMD was calculated for each femoral region. BMD values were adjusted peri-prosthetically to account for stem area.

Secondary Outcomes

  • Baseline Harris Hip Score (HHS) at Preoperative Visit(Preoperative)
  • Radiographic Assessment at 3 Month Visit (Yes/No Components)(3 Months)
  • Radiographic Assessment at Discharge Visit(Discharge)
  • Harris Hip Score (HHS) at 3 Month Visit(3 Month)
  • Hip Injury Osteoarthritis Outcome Score (HOOS) at 5 Year Visit(5 Years)
  • Radiographic Assessment at 3 Month Visit(3 Months)
  • Radiographic Assessment at 5 Year Visit(5 Year)
  • Radiographic Assessment at 3 Month Visit (Neutral/Valgus Component)(3 Months)
  • Harris Hip Score (HHS) at 6 Month Visit(6 Months)
  • Harris Hip Score (HHS) at 5 Year Visit(5 Year)
  • Hip Injury Osteoarthritis Outcome Score (HOOS) at Preoperative Visit(Preoperative)
  • Hip Injury Osteoarthritis Outcome Score (HOOS) at 2 Year Visit(2 Years)
  • Harris Hip Score (HHS) at 2 Year Visit(2 Years)
  • Hip Injury Osteoarthritis Outcome Score (HOOS) at 6 Month Visit(6 Months)
  • Radiographic Assessment at 5 Year Visit (Yes/No Components)(5 Year)
  • Radiographic Assessment at 1 Year Visit(1 Year)
  • Harris Hip Score (HHS) at 1 Year Visit(1 Year)
  • Hip Injury Osteoarthritis Outcome Score (HOOS) at 3 Month Visit(3 Months)
  • Hip Injury Osteoarthritis Outcome Score (HOOS) at 1 Year Visit(1 Year)
  • Radiographic Assessment at 1 Year Visit (Yes/No Components)(1 Year)
  • Radiographic Assessment at Discharge Visit (Neutral/Valgus Component)(Discharge)
  • Radiographic Assessment at 1 Year Visit (Neutral/Valgus Component)(1 Year)
  • Radiographic Assessment at Preoperative Visit (Yes/No Components)(Discharge)
  • Radiographic Assessment at 5 Year Visit (Neutral/Valgus Component)(5 Years)

Study Sites (1)

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