Use Dual-energy X-ray Absorptiometry and Quantitative Microradiography to Predict the Periprosthetic Bone Loss in Distal Femur After Total Knee Arthroplasty
Overview
- Phase
- Not Applicable
- Intervention
- Not specified
- Conditions
- Periprosthetic Bone Loss in Total Knee Replacement
- Sponsor
- National Taiwan University Hospital
- Enrollment
- 50
- Locations
- 1
- Primary Endpoint
- change in bone mineral density
- Last Updated
- 13 years ago
Overview
Brief Summary
The investigators hypothesized that the microarchitecture of bone influence the degree of periprosthetic bone loss after total knee arthroplasty surgery. The investigators collected the bone fragment at the distal femur while performing total knee replacement and take quantitative radiography analysis . Before and after the surgery(6 month ,12 month) , the investigators check the BMD at identical location of the distal femur by using dual energy absorptiometry. The investigators will use linear regression to evaluate the relationship between the microarchitecture and the degree of bone loss.
Investigators
National Taiwan University Hospital
Use dual-energy x-ray absorptiometry and quantative microradiography to predict the periprosthetic bone loss in distal femur after total knee arthroplasty
National Taiwan University Hospital
Eligibility Criteria
Inclusion Criteria
- •severe knee osteoarthritis
- •post menopausal women
Exclusion Criteria
- •immune disease
- •end stage of renal disease who receive dialysis
- •history of fracture at ipsilateral distal femur
Outcomes
Primary Outcomes
change in bone mineral density
Time Frame: before the surgery and after the sugery (6month ,12month)
Use dual energy x-ray absorptiometry to detect to BMD at the distal femur