Effect of Rupatadine compared to placebo in the reducing complications of acute dengue infection

Centre for Dengue Research, University of Sri Jayawardenapura0 个研究点目标入组 240 人开始时间: 待定最近更新: 2024年8月20日

适应症

试验速览

暂无简介。

•1. Confirmed dengue infection (positive dengue NS1 antigen detection test or presence of dengue specific antibodies)
•2. Informed written consent
•3. Age: between 18-60 years
•4. Duration of illness: less than 5 days
•5. No evidence of vascular leak.

•1. Pregnancy
•2. Known allergies to antihistamines
•3. Individuals who are homeless
•4. Dependency on alcohol or abuse drugs
•5. Hepatic impairment defined as: no previously known liver disease, prolonged prothromin time of 4-6 seconds or more, INR of >1.5
•6. Renal impairment defined as: hypertension and diabetes, GFR <60 ml/min per 1.73 m2, urinary albumin-to-creatinine ratio >30 mg/g , hereditary kidney disease, recurrent or extensive nephrolithiasis, urinary red cell casts, red blood cell count >20 per high power field, Consistent albuminuria

发起方

Centre for Dengue Research, University of Sri Jayawardenapura