se of Rupatadine in the treatment of acute dengue infectio

Phase 2

Recruiting

• Conditions: Dengue

• Registration Number: SLCTR/2014/023
• Lead Sponsor: Centre for Dengue Research, University of Sri Jayawardenapura

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Last Update Posted: 2024-08-20

Recruitment & Eligibility

• Status: Recruiting
• Sex: Not specified
• Target Recruitment: 240

Inclusion Criteria

1. Confirmed dengue infection (positive dengue NS1 antigen detection test or presence of dengue specific antibodies)
2. Informed written consent
3. Age: between 18-60 years
4. Duration of illness: less than 5 days
5. No evidence of vascular leak.

Exclusion Criteria

1. Pregnancy
2. Known allergies to antihistamines
3. Individuals who are homeless
4. Dependency on alcohol or abuse drugs
5. Hepatic impairment defined as: no previously known liver disease, prolonged prothromin time of 4-6 seconds or more, INR of >1.5
6. Renal impairment defined as: hypertension and diabetes, GFR <60 ml/min per 1.73 m2, urinary albumin-to-creatinine ratio >30 mg/g , hereditary kidney disease, recurrent or extensive nephrolithiasis, urinary red cell casts, red blood cell count >20 per high power field, Consistent albuminuria

Study & Design

• Study Type: Interventional
• Study Design: Not specified