Impact of Neuromonitoring During Cardiothoracic Procedures: A Retrospective Analysis
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 入组人数
- 250,000
- 试验地点
- 1
- 主要终点
- Acute Kidney Injury: Incidence of acute kidney injury identified by ICD-9 diagnosis code
研究概览
简要总结
Through a series of sequential analyses, retrospective database exploration looking for linkages and associations between the use of processed electroencephalogram (EEG) and/or cerebral saturation monitoring and patient outcomes post-cardiothoracic surgery will be explored.
详细描述
The purpose of this study is to mine the Premier Healthcare Database to:
- define the incidence of post-operative cognitive complications, acute kidney injury and stroke after specific cardiac surgical procedures (defined as: coronary artery bypass graft [CABG], Aortic Valve Replacement, Mitral valve repair, Mitral valve replacement, thoracic aortic operation, combined CABG and Valve replacement or repair ; and
- Determine the incremental increase in the length of hospitalization and cost of hospitalization among cardiac surgical patients who suffer postoperative cognitive complications, acute kidney injury and stroke; and
- Determine the effectiveness of intraoperative neuromonitoring with cerebral saturation and/or processed electroencephalogram (EEG) monitoring on the incidence of post-operative cognitive complications, acute kidney injury and stroke as a consequence of specific cardiac surgery procedures.
The Premier Healthcare Database is a privately owned database that represents approximately 1/5th of all United States hospitalizations annually. It includes all International Classification of Diseases-9th Revision (ICD-9) and International Classification of Diseases-Clinical Modification (ICD-9-CM) diagnosis and procedure codes recorded by the hospital, as well as a limited set of Current Procedural Terminology (CPT)-4 codes. Within the database, discharge-level data include information on patient and provider characteristics, diagnoses and procedures, hospital resource utilization, and charges/cost data for all entries, including pharmacy charges.
研究设计
- 研究类型
- Observational
- 观察模型
- Cohort
- 时间视角
- Retrospective
入排标准
- 年龄范围
- 18 Years 至 100 Years（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 是
入选标准
- •All adult (age >=18 years) hospitalized patients who underwent major cardiac surgical procedure requiring cardiopulmonary bypass captured in the premier database from January 1, 2010 - December 31, 2014 (5 year period)
排除标准
- •<18 years of age
- •Cardiac procedures not requiring cardiopulmonary bypass
结局指标
主要结局
Acute Kidney Injury: Incidence of acute kidney injury identified by ICD-9 diagnosis code
时间窗: 5 years
Incidence of acute kidney injury identified by ICD-9 diagnosis code
Delirium: Incidence of post-operative cognitive complications identified by ICD-9 diagnosis code
时间窗: 5 years
Incidence of post-operative cognitive complications identified by International Classification of Disease (ICD-9) diagnosis code
Stroke: Incidence of stroke identified by ICD-9 diagnosis code
时间窗: 5 years
Incidence of stroke identified by ICD-9 diagnosis code
次要结局
未报告次要终点