Retrospective Study to Identify Correlations Between the Clinical Parameters, Analytics and Neuroimaging Data in Patients That Suffered of Intraparenchymal Cerebral Hemorrhage
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 发起方
- 入组人数
- 137
- 试验地点
- 1
- 主要终点
- Hematoma growth
研究概览
简要总结
This is a retrospective observational study to investigate the clinical, analytical and neuroimaging data generated during routine clinical management of intracerebral hemorrhage. The study will review the data from about 500 patients attended during the last ten years in the Neurology Department of Hospital Parc Taulí de Sabadell.
The aim is to measure the size of the lesion in neuroimage (TC and MRI), the edema, the alterations in diffusion weighted images and to correlate this data with clinical parameters and analytical measurements. With this approach investigators plan to investigate the incidence of hematoma growth, the role of perilesional edema and diffusion changes, and the relation between neuroimaging findings and clinical outcome. The study also try to establish significant correlations between clinical and analytical data, the clinical outcome and and the magnitude of changes in neuroimaging.
研究设计
- 研究类型
- Observational
- 观察模型
- Case Only
- 时间视角
- Retrospective
入排标准
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Patients who have been attended at the Hospital Parc Taulí for the last 10 years after presenting an intraparenchymal hemorrhage.
- •The patients have had to undergo a computed tomography at the admission and a cranial magnetic resonance during the hospitalization in the time course specified in point in the protocol
- •The patients must present in their clinical story the analytical determinations detailed in the protocol.
排除标准
- •Intracerebral hemorrhage secondary to head trauma
- •Intracerebral hemorrhage secondary to neoplasm
结局指标
主要结局
Hematoma growth
时间窗: 2 days
Difference of hematoma size between CT conducted at admission and MRI conducted during follow up
Correlation between hematoma growth and analytical parameters
时间窗: 2 days
Determine the analytical parameters related with hematoma growth
Correlation between clinical parameters and the size of alterations in DWI
时间窗: 2 days
Determine the relationship between clinical parameters and the size of alterations in DWI
Alterations in DWI
时间窗: 2 days
Size of alterations in diffusion weighted image
Correlation between analytical parameters and the size of alterations in DWI
时间窗: 2 days
Determine the relationship between analytical parameters and the size of alterations in DWI
Correlation between hematoma growth and clinical paramenters
时间窗: 2 days
Determine the clinical parameters related with hematoma growth
Correlation between perilesional edema size and clinical outcome
时间窗: 1 month
Determine the relationship between the size of edema and clinical outcome
Perilesional edema
时间窗: 2 days
Size of edema measured in FLAIR sequences
Correlation between clinical parameters and the size of edema measured in FLAIR sequences
时间窗: 2 days
Determine the relationship between clinical parameters and the size of edema
Correlation between analytical parameters and the size of edema measured in FLAIR sequences
时间窗: 2 days
Determine the relationship between analytical parameters and the size of edema
Correlation between hematoma growth and clinical outcome
时间窗: 1 month
Determine the impact of hematoma growth on clinical outcome
Correlation between the clinical parameters and clinical outcome
时间窗: 1 month
Determine the relationship between the clinical parametes and clinical outcome
Correlation between the analyticial parameters and clinical outcome
时间窗: 1 month
Determine the relationship between the analytical parametes and clinical outcome
Correlation between the size of DWI alterations and clinical outcome
时间窗: 1 month
Determine the relationship between the size of DWI alterations and clinical outcome
次要结局
未报告次要终点
研究者
Santiago Rojas Codina MD PhD
Principal investigator
Universitat Autonoma de Barcelona