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Clinical Trials/NCT04734223
NCT04734223
Completed
Not Applicable

Correlation of Neuroimaging Findings With Clinical Presentation and Laboratory Data in Patients With COVID-19: A Single Center Study

Saglik Bilimleri Universitesi Gazi Yasargil Training and Research Hospital1 site in 1 country436 target enrollmentApril 1, 2020

Overview

Phase
Not Applicable
Intervention
Not specified
Conditions
Neuroimaging
Sponsor
Saglik Bilimleri Universitesi Gazi Yasargil Training and Research Hospital
Enrollment
436
Locations
1
Primary Endpoint
Frequency of acute thromboembolism in COVID-19 patients undergoing neuroimaging
Status
Completed
Last Updated
5 years ago

Overview

Brief Summary

This study aimed to discuss the neuroimaging findings and indications, epidemiological data, laboratory values, and the relationship of these variables with mortality in patients with COVID-19.

Detailed Description

COVID-19 can present as neurological symptoms such as anosmia, headache, taste perversion, dizziness, syncope, and altered state of consciousness. It has been reported in previous studies that thromboembolic ischemic and hemorrhagic strokes associated with COVID-19 have been observed in the early period. It has been suggested that conditions characterized by neurological sequelae, such as encephalitis and encephalopathy, ataxic seizures, Guillain-Barré syndrome (GBS), demyelinating diseases, and neuromuscular disorders may occur in the longer term.In the present study, the investigators aimed to reveal the findings of neuroimaging analyses performed in patients followed up with a diagnosis of COVID-19 who had neurological symptoms, discuss the relationship of these findings with laboratory and epidemiological data, and emphasize that CNS involvement in these patients should not be overlooked. In this study, 436 patients with COVID-19 who underwent at least one neuroimaging procedure during April 2020-December 2020 due to neurological symptoms and whose diagnosis was confirmed by reverse transcriptase-polymerase chain reaction test were included. Although computed tomography was predominantly used for imaging, magnetic resonance imaging was also used when necessary. The patients were grouped based on imaging findings, and statistical evaluations were made between the groups.

Registry
clinicaltrials.gov
Start Date
April 1, 2020
End Date
December 31, 2020
Last Updated
5 years ago
Study Type
Observational
Sex
All

Investigators

Sponsor
Saglik Bilimleri Universitesi Gazi Yasargil Training and Research Hospital
Responsible Party
Principal Investigator
Principal Investigator

Seyhmus Kavak

MD, Radiologist

Saglik Bilimleri Universitesi Gazi Yasargil Training and Research Hospital

Eligibility Criteria

Inclusion Criteria

  • COVID-19 RT-PCR positivity-
  • older than 18 years old

Exclusion Criteria

  • younger than 18 years old

Outcomes

Primary Outcomes

Frequency of acute thromboembolism in COVID-19 patients undergoing neuroimaging

Time Frame: Between April and December 2020

Acute thromboembolic events are common in COVID-19 subjects undergoing neuroimaging, potentially due to an increased procoagulant process.

Study Sites (1)

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