Eyelid Position Interdependence in Involutional Ptosis Patients Submitted to 10% Phenylephrine
- Conditions
- Blepharoptosis
- Registration Number
- NCT00864656
- Lead Sponsor
- University of Sao Paulo
- Brief Summary
The primary aim of this study is to quantify eyelid position changes in tested and opposite eyes in ptosis patients submitted to 1, 2 or 4 drops of 10% phenylephrine in one eye. The secondary objective is to correlate the eye dominance, severity and laterality of ptosis with eyelid position changes in these 3 groups.
- Detailed Description
This is a prospective observational study conducted in involutional ptosis patients, which will be submitted to instillation of a single drop of 10% phenylephrine in one eye(Group 1), 2 drops (G2) or 4 drops ( G3).
Video camera will record the images of both eyes before and after drug application at 3, 10, 15 and 30 minutes. The images will be edited to analyze upper and lower lid height.
Recruitment & Eligibility
- Status
- COMPLETED
- Sex
- All
- Target Recruitment
- 60
- Involutional blepharoptosis
- Upper Margin-reflex distance less or equal 2.0mm
- Good fixation and collaboration
- Previous eyelid surgeries
- Use of adrenergic or sympathicomimetics drugs
- Myopathies
- Thyroid orbitopathy
- Non-controlled cardiovascular disease
Study & Design
- Study Type
- OBSERVATIONAL
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Upper lid height before and after phenylephrine test lower lid height before and after phenylephrine test 3, 10, 15 and 30 minutes
- Secondary Outcome Measures
Name Time Method Scobee test to detect eye dominance 15 minutes before 10% phenylephrine instillation
Trial Locations
- Locations (1)
Ophthalmology Dept. University of Sao Paulo General Hospital
🇧🇷Sao Paulo, Brazil