A Prospective Study on the Association Between Graves' Orbitopathy and Hypercholesterolemia
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 入组人数
- 250
- 试验地点
- 1
- 主要终点
- Relationship between LDL cholesterol levels and Graves' Orbitopathy
研究概览
简要总结
The investigators have recently observed retrospectively that the occurrence of Graves' Orbitopathy in patients with Graves' disease is less frequent in patients with normal cholesterol levels, in line with another recent observation suggesting that statins play a protective role in Graves' patients from developing Graves' Orbitopathy. The present study is designed in order to investigate the possible association between Graves' Orbitopathy and high cholesterol level as well as the relation between Graves' Orbitopathy degree and high cholesterol level
研究设计
- 研究类型
- Observational
- 观察模型
- Cohort
- 时间视角
- Cross Sectional
入排标准
- 年龄范围
- 18 Years 至 80 Years（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Graves' disease with Graves' Orbitopathy
- •Graves' disease without Graves' Orbitopathy
排除标准
- •Previous treatment with radioiodine
- •Previous treatment with thyroidectomy
结局指标
主要结局
Relationship between LDL cholesterol levels and Graves' Orbitopathy
时间窗: Baseline
Relationship between the levels of LDL cholesterol and the presence of Graves' Orbitopathy
次要结局
- Relationship between LDL cholesterol levels and the activity of Graves' Orbitopathy(Baseline)
- Relationship between LDL cholesterol levels and the severity of Graves' Orbitopathy(Baseline)
研究者
Marinò Michele
Ricercatore (Assistant Professor)
University of Pisa