Efficacy and safety of greenpropolis against prostate cancer with biochemical recurrence after radical prostatectomy
Not Applicable
Completed
- Conditions
- Prostate cancer
- Registration Number
- JPRN-UMIN000023451
- Lead Sponsor
- Kyoto University Graduate School of Medicine
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Complete: follow-up continuing
- Sex
- Male
- Target Recruitment
- 40
Inclusion Criteria
Not provided
Exclusion Criteria
Previously treated or currently be receiving hormonal therapy with the intent to treat prostate cancer (surgical castration or other hormonal manipulation, e.g. GnRH agonists or antagonists, anti-androgens or estrogens); Evidence of administration of greenpropolis or other alternative therapies within 3 months before day 1. History of allergy against honey, a coniferous tree, a poplar, Peru balsam, and salicylic acid; History of atopic dermatitis, chronic recurrent eczema, and asthma.
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method PSA response rate
- Secondary Outcome Measures
Name Time Method PSA response duration time to PSA progression PSA slope before and after administration of propolis Changes of serum testosterone level IHC of AKR1C3, AR, and ERG of prostatectomy specimens QOL Proportion of adverse events