Assessment of Circulating Fubctional Mitochondrias in Vitiligo Patients

Not Applicable

Active, not recruiting

• Conditions: Skin and Connective Tissue Diseases
• Interventions: Other: Non segmental vitiligo; Other: Health Volunteers

• Registration Number: NCT05525741
• Lead Sponsor: Centre Hospitalier Universitaire de Nice

Brief Summary

To compare the level of circulating functional mitochondria in the serum of vitiligo patients as compared to controls

Detailed Description

Not available

Study Timeline

• Study First Submitted: 2022-08-23
• Study First Submitted QC: 2022-08-30
• Study First Posted: 2022-09-02
• Study Start: 2022-10-19
• Primary Completion: 2023-04-01
• Status Verified: 2024-12
• Last Update Submitted: 2024-12-03
• Last Update Posted: 2024-12-04
• Study Completion: 2025-06-30

Recruitment & Eligibility

• Status: ACTIVE_NOT_RECRUITING
• Sex: All
• Target Recruitment: 59

Inclusion Criteria

• Patients with non segmental vitiligo,
• atopic dermatitis, psoriais, alopecia areata,
• 1st degree relative of vitiligo patients.

Exclusion Criteria

• segmental or mixed vitiligo,
• personnal history of other autoimmune disorders,
• oral use of antioxidant,
• pregant women

Study & Design

• Study Type: INTERVENTIONAL
• Study Design: PARALLEL

Arm && Interventions

Group	Intervention	Description
Vitiligo Group	Non segmental vitiligo	If the subject consents and they meet all the criteria a 20 ml blood sample will be taken.
Volunteers Group	Health Volunteers	If the subject consents and they meet all the criteria a 20 ml blood sample will be taken.

Primary Outcome Measures

Name	Time	Method
Total number of circulating functionnal mitochondria (CFM) in the plasma	at baseline	Level of CFM in vitiligo serum as compared to controls

Secondary Outcome Measures

Name	Time	Method
measuring the functionality of circulating mitochondria	At baseline	Functional analysis of CFM in vitiligo patients as compared to controls analyzed by MFI Mito Tracker

Trial Locations

Locations (1)

CHU de Nice - Hôpital de l'Archet; 🇫🇷 Nice, Alpes-maritimes, France