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Clinical Trials/NCT05944081
NCT05944081
Withdrawn
Not Applicable

Multicenter, Not Randomised, Non-interventional, Postmarket Clinical Follow-Up (PMCF) Study on the Performance / Safety of Arcadius XP L® Interbody Fusion Device

Aesculap AG3 sites in 1 country60 target enrollmentMarch 15, 2024

Overview

Phase
Not Applicable
Intervention
Not specified
Conditions
Chronic Low-back Pain
Sponsor
Aesculap AG
Enrollment
60
Locations
3
Primary Endpoint
Functional outcome after minimum 1 year postoperatively
Status
Withdrawn
Last Updated
7 months ago

Overview

Brief Summary

The purpose of this study is to collect clinical and radiological mid-term (min. 1 year) data on the ArcadiusXP L® lumbar stand-alone cage in a post-market clinical follow-up study (PMCF) limited to 60 patients.

Registry
clinicaltrials.gov
Start Date
March 15, 2024
End Date
December 12, 2025
Last Updated
7 months ago
Study Type
Observational
Sex
All

Investigators

Responsible Party
Sponsor

Eligibility Criteria

Inclusion Criteria

  • all patients who received a Arcadius XP L® interbody fusion device between 2016 until approx. January 2021 (minimum Follow-up is one year) in the study center
  • all indications as given by the instructions for use: degenerative disc disease (DDD), Instability, Spondylolisthesis up to grade 1, Post-discectomy syndrome, Post-traumatic instability
  • Written informed consent for the documentation of clinical and radiological results

Exclusion Criteria

  • Patient is not willing or able to participate at the follow-up examination
  • Patients living outside a radius of 100 km around the study center
  • all contraindications as given by the instructions for use:

Outcomes

Primary Outcomes

Functional outcome after minimum 1 year postoperatively

Time Frame: at follow-up approximately 1 year postoperatively

The Oswestry Disability Index (ODI) is designed to measure back-specific disability. The questionnaire is self-administered and has 10 items concerning pain and activities of daily living including personal care, lifting, walking, sitting, standing, sleeping, sex life, social life and travelling. It is a self-administered questionnaire Each section is scored on a 0-5 scale, 5 is for maximum disability. The index is calculated by dividing the total score by the total possible score, which is multiplied by 100 and expressed as a percentage. The scores for all questions answered are summed, then multiplied by two to obtain the index (range 0 to 100). Zero is equated with no disability and 100 is the maximum disability possible.

Secondary Outcomes

  • Radiological Outcome: Bone fusion(at follow-up approximately 1 year postoperatively)
  • Rate of (Serious) adverse events(at follow-up approximately 1 year postoperatively)
  • Pain assessment(at follow-up approximately 1 year postoperatively)
  • Development Quality of life (EQ-5D-5L)(at follow-up approximately 1 year postoperatively)

Study Sites (3)

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