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Investigating the effect of Albumin on urine output, using it with lasix and mannitol in ICU patients with oliguria

Phase 2
Conditions
Acute renal failure.
Acute renal failure, unspecified
Registration Number
IRCT2016013010741N3
Lead Sponsor
Vice chancellor for research, Kerman University of Medical Sciences
Brief Summary

Not available

Detailed Description

Not available

Recruitment & Eligibility

Status
Complete
Sex
All
Target Recruitment
100
Inclusion Criteria

oliguric patients in ICU; patients with Acute Renal Failure.
Exclusion criteria: history of kidney disorders (Cr>1.5mg/dl); proteinuria (urine pr>3.5g/d); kidney disorders like glomerulonephritis and ATN; consumption of furosemide within last two weeks; incorrect urine collection; urine line blockage; low level of albumin (below 4.5 mg/dl).

Exclusion Criteria

Not provided

Study & Design

Study Type
interventional
Study Design
Not specified
Primary Outcome Measures
NameTimeMethod
Serum BUN level. Timepoint: At the time of admission and then daily. Method of measurement: Blood test.;Serum Cr level. Timepoint: At the time of admission and then daily. Method of measurement: Blood test.
Secondary Outcome Measures
NameTimeMethod
Daily urine output. Timepoint: During hospital stay daily. Method of measurement: Documentation of collected urine in 24 hours.;Glomerular filtration rate (GFR). Timepoint: Every day during hospital stay. Method of measurement: By means of creatinine clearance equation.;CVP. Timepoint: Before commerce of diuresis and during therapeutic period. Method of measurement: Monitoring device.;Superficial edema. Timepoint: Before commerce of diuresis and during therapeutic period. Method of measurement: Examination.
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