NCT01091753已完成4 期
Effect of Nocturnal Administration of Anti-hypertensive Medications in NoN-dippers
适应症
干预措施
相关药物
试验速览
- 阶段
- 4 期
- 状态
- 已完成
- 入组人数
- 28
- 试验地点
- 1
- 主要终点
- IMT(intima media thickness) Measure data(Sono)
研究概览
简要总结
The purpose of this study is to determine the effect of nocturnal administration of Anti-hypertensive medications in Non-dippers.
Efficacy variables.
- ECHO
- 24hr. horter
- IMT
- BUN/crea, urine analysis (microalbulinuria
- Cardio vascular event. "
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 主要目的
- Treatment
- 盲法
- None
入排标准
- 年龄范围
- 18 Years 至 70 Years（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Essential hypertension (stage 1-2)
- •24hr. holer : non-dipper
- •Age 18 ~70.
排除标准
- •Any known malignant disease
- •Renal failure , creatinine >2.0mg/dl
- •Liver disease
研究组 & 干预措施
morning administration group
Placebo Comparator
干预措施: Valsaltan, amlodipine (Drug)
nocturnal administration group
Experimental
干预措施: Valsaltan, amlodipine (Drug)
结局指标
主要结局
IMT(intima media thickness) Measure data(Sono)
时间窗: 36 months
次要结局
未报告次要终点
研究者
研究点 (1)
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