A clinical trial to study the effects of two drugs,Dexmedetomidine and Fentanyl during pneumoperitonium in laproscopic cholecystectomy.
Not Applicable
Completed
- Conditions
- Health Condition 1: K800- Calculus of gallbladder with acutecholecystitis
- Registration Number
- CTRI/2019/07/019958
- Lead Sponsor
- Department of Anaesthesiology Medical CollegeJaipur
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Completed
- Sex
- Not specified
- Target Recruitment
- 84
Inclusion Criteria
1.Patients with ASA grade I and II
2.Patients willing to give written informed consent.
3.Age Groups 18 to 50 years
4.Weighing 40 to 70 kg.
5.Scheduled for elective laparoscopic cholecystectomy
Exclusion Criteria
1.Patients not willing to participate in study
2.Patients having history of allergy to anaesthestic agents used in study
3.Patients with pre-existing cardiac disease, Hypertension ,Asthama,Renal or Hepatic dysfunction
4.Patients with anticipated difficult intubation i.e Mallampati class 3 or more,restricted neck movement or restricted mouth opening.
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method To assess and compare the change in hemodynamic variables (HR,SBP,DBP,MAP) after pneumoperitoneum in both the study groups. <br/ ><br> <br/ ><br>Timepoint: Data will be recorded Just Before induction,1min after induction,1 min after intubation,3min after intubation,1min after PNP and 10min interval in PNP throughout the surgery and after extubation
- Secondary Outcome Measures
Name Time Method 1. To assess and compare the duration of post operative analgesia in both the study groups. <br/ ><br>2. To determine post-operative sedation level in both the study groups. <br/ ><br>3. To determine the incidence of side effects if any in both the study groups.Timepoint: Post-operative sedation level will be measured by using RAMSAY SEDATION SCORE in every 30min. after extubation.POST-OPERATIVE ANALGESIA Evaluated by Visual analogue scale(VAS) in every 30min. upto Giving First Rescue Analgesia. <br/ ><br>