A study to compare dexmedetomidine (sedative and analgesic) and fentanyl (sedative and analgesic) on propofol (sedative and hypnotic) requirement in surgeries done under general anesthesia without muscle relaxant
Not Applicable
- Conditions
- Health Condition 1: O- Medical and Surgical
- Registration Number
- CTRI/2022/01/039438
- Lead Sponsor
- izams Institute of Medical sciences
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- ot Yet Recruiting
- Sex
- Not specified
- Target Recruitment
- 0
Inclusion Criteria
1. ASA class I and II, 2. Age â?? 18 to 60 years, 3. Patients of either sex, 4. Patients undergoing elective brachial plexus repair surgeries
Exclusion Criteria
1. Patients who are not willing to participate or not co-operative
2. Pregnant or lactating women
3. ASA Grade-III and IV
4. Haemodynamic instability
5. Patients with significant hepatic, renal, cardiac, neurologic and psychiatric illness
6. Patients with history of drug sensitivity to study drugs
7. Patients with hypertriglyceridemia
8. Patients on beta-blockers, sedative drugs and analgesics
9. Pseudocholinesterase deficiency and hyperkalemia
10. Body mass index greater than or equal to 30
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method comparison of total propofol requirement in propofol-dexmedetomidine and propofol-fentanyl infusion groups in patients undergoing elective brachial plexus repair surgeries under general anesthesia with entropy guidanceTimepoint: Intraoperative period
- Secondary Outcome Measures
Name Time Method Comparison of intraoperative hemodynamics between two groups <br/ ><br> <br/ ><br>Comparison of Extubation Quality Score between two groups <br/ ><br> <br/ ><br>Comparison of postoperative sedation using Ramsay Sedation Scale between two groupTimepoint: Intraoperative period and postoperative period ( upto 1 hour )