Effect of Different NanoScaffolds on Pulp Regeneration in Non-Vital Immature Permanent Teeth (Randomized Clinical Trial)
Not Applicable
Active, not recruiting
- Conditions
- Necrotic Immature Permanent Incisors
- Registration Number
- NCT07121348
- Lead Sponsor
- Tanta University
- Brief Summary
the clinical trial aims to evaluate efficency of different scaffolds in cases of regeneration
- Detailed Description
The aim of this study is to evaluate the clinical and radiographic outcome of regenerative endodontic procedures in immature non-vital permanent teeth using different nanoscaffolds (Platelet-rich fibrin, Mesoporous silica nanoparticles, Hyaluronic acid nanoparticles, Pomegranate nanoparticles)
Recruitment & Eligibility
- Status
- ACTIVE_NOT_RECRUITING
- Sex
- All
- Target Recruitment
- 40
Inclusion Criteria
• Patients free from any systemic diseases that may interfer with the normal healing process.
- Maxillary traumatized or cariously exposed non-vital immature anterior teeth.
- Teeth don't need for post and core as a final restoration.
- Radiographic evidence of an apical opening width more than 2 mm with or without periapical radiolucency.
- Teeth without anatomical variations
Exclusion Criteria
• Immunocompromised patients
- Teeth with previous endodontic treatment.
- Teeth with internal or external resorption
- Radiographic evidence of root fracture.
- Lack of patient and parent cooperation.
- Presence of periodontal pocket depth more than 4 mm.
Study & Design
- Study Type
- INTERVENTIONAL
- Study Design
- PARALLEL
- Primary Outcome Measures
Name Time Method apical closure assessed radiographically 12 months after treatment radiographic evaluation of apical closure as reduction or elimination of the apical opening of the root
- Secondary Outcome Measures
Name Time Method
Trial Locations
- Locations (1)
Faculty of Dentistry,Tanta University
🇪🇬Tanta, Gharbia, Egypt
Faculty of Dentistry,Tanta University🇪🇬Tanta, Gharbia, Egypt