CTRI/2025/07/091472已完成4 期
Effects of gallbladder bed irrigation with Ropivacaine vs Normal Saline on Pulmonary functions of patients undergoing laparoscopic cholecystectomy.
Moksha Joshi1 个研究点 分布在 1 个国家目标入组 70 人开始时间: 2025年8月4日最近更新:
试验速览
- 阶段
- 4 期
- 状态
- 已完成
- 发起方
- 入组人数
- 70
- 试验地点
- 1
- 主要终点
- FEV1, FVC, FEF 25-75
研究概览
简要总结
hypothesis - Gallbladder bed irrigation with ropivacaine, when used as an adjunctive technique during laparoscopic cholecystectomy, will result in improved pulmonary functions compared to standard laparoscopic cholecystectomy without ropivacaine irrigation.
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 盲法
- Participant and Outcome Assessor Blinded
入排标准
- 年龄范围
- 18.00 Year(s) 至 65.00 Year(s)（—）
- 性别
- All
入选标准
- •The patients who were willing to participate in study and had given written, valid and informed consent. Age.
- •18-65 years Patients posted for laparoscopic cholecystectomy American Society of Anaesthesiologist grade I and II Patients belonging to either gender.
排除标准
- •Patient refusal to be part of the study.
- •Patients with known allergies or contraindications to ropivacaine, the agent used for gallbladder bed irrigation.
- •Pregnancy or Lactation: Pregnant or lactating patients, as the safety of ropivacaine use during pregnancy and lactation, is not established.
- •Chronic Respiratory Conditions; Severe Cardiovascular Disease; Severe Liver or kidney disease; acute cholecystitis, choledocholithiasis History of Allergic Reactions; Current Medications; Patients currently taking medications that may interact with ropivacaine (eg Fluvoxamine, cimetidine, ciprofloxacin, ketoconazole, verapamil, amiodarone) or affect pulmonary function particularly medications that influence neuromuscular function (eg aminoglycosides, magnesium, or chronic steroids) or respiratory depression (eg Opioids, benzodiazepines, barbiturates).
结局指标
主要结局
FEV1, FVC, FEF 25-75
时间窗: Baseline, 6 hours, 8 hours, 12 hours, 24 hours
次要结局
- Visual Analog Scale, BHT, SBC, Cough test
研究者
Moksha Joshi
Grant Government Medical College and Sir J.J. Group of hospitals
研究点 (1)
Loading locations...
相似试验
尚未招募
不适用
To compare spinal administration of morphine alone versus morphine with bupivacaine for pain relief during and after surgery in patients undergoing surgeries of liver or gall bladder.CTRI/2024/12/078658Bangalore Medical College and Research Institute60
尚未招募
不适用
Dexmedetomidine as an adjuvant to ropivacaine infiltration for postoperative analgesia in pediatric tonsillectomy:a randomised controlled studyCTRI/2025/08/093524Maulana Azad Medical College90
尚未招募
3 期
Comparing Ropivacaine Alone vs. Ropivacaine with Dexmedetomidine for Pain Relief After Laparoscopic Gallbladder Surgery: A Randomized Controlled TrialCTRI/2025/08/093287Dr Mayank Chauhan80
尚未招募
2 期
To compare Ropivacaine and Bupivacaine in subcostal transverse abdominis plane block for post operative analgesiaCTRI/2025/11/097579Netaji Subhash Medical College and Hospital60
招募中
4 期
Evaluation of postoperative recovery when combining intravenous lidocaine with ropivacaine infiltration in laparoscopic colorectal oncologic surgery: a randomized controlled trial2025-523207-29-00Centre Hospitalier Universitaire Amiens Picardie182