Comparative study between 0.375% Ropivacaine and 0.25% Bupivacaine in ultrasound guided bilateral subcostal transverse abdominis plane block for post-operative analgesia in patients undergoing laparoscopic cholecystectomy
Trial Snapshot
- Phase
- Phase 2
- Status
- Not yet recruiting
- Sponsor
- Enrollment
- 60
- Locations
- 1
- Primary Endpoint
- To compare post operative NRS score for pain
Study Overview
Brief Summary
Post operative pain remains a significant concern following laparoscopic cholecytectomy, affecting patient comfort, recovery, potential for same day discharge and overall satisfaction. With the widespread availability of ultrasound guidance for more accurate localization of transverse abdominis plane, the block is considered as an important technique for reduction of post operative pain in abdominal surgeries. in view of above, this study is being undertaken whether ropivacaine with its inherent advantages is superior to bupivaciane for providing post-operative analgesia when used for tranverse abdominis plane block in patients undergoing laparoscopic cholecytectomy.
Study Design
- Study Type
- Interventional
- Allocation
- Randomized
- Masking
- Participant and Investigator Blinded
Eligibility Criteria
- Ages
- 18.00 Year(s) to 60.00 Year(s) (—)
- Sex
- All
Inclusion Criteria
- •American Society of Anesthesiology 1 and 2 of either sex posted for 4 port laparoscopic cholecystectomy.
Exclusion Criteria
- •patients with history of allergy to local anesthetic drug, psychiatric illness, substance abuse, opioid intolerance, any uncompensated systemic illness, pregnant women.
Outcomes
Primary Outcomes
To compare post operative NRS score for pain
Time Frame: 10 minutes, 30 minutes, 1 hour and then every 4 hours for next 24 hours
Secondary Outcomes
- 1)To compare postoperative diclofenac sodium need as rescue analgesia(2)To compare hemodynamic between both groups.)
Investigators
A Likhil Kumar Reddy
Netaji Subhash Medical College and Hospital